{"result":[{"lastName":"Felsher","clinicalFocus":[{"focus":"Hodgkin's Disease"},{"focus":"Hodgkin's Disease - Hematology"},{"focus":"Hodgkin's Disease - Medical Oncology"},{"focus":"Lymphoma "},{"focus":"Oncology (Cancer)"},{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Pathology"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5931&type=small&showNoImage","displayName":"Dean W. Felsher","firstName":"Dean","href":"http://med.stanford.edu/profiles/Dean_Felsher","researchInterest":"My laboratory investigates how oncogenes initiate and sustain tumorigenesis. I have developed model systems whereby I can conditionally activate oncogenes in normal human and mouse cells in tissue culture or in specific tissues of transgenic mice. In particular using the tetracycline regulatory system, I have generated a conditional model system for MYC-induced tumors. I have shown that cancers caused by the conditional over-expression of the MYC proto-oncogene regress with its inactivation."},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Sikic","clinicalFocus":[{"focus":"Medical Oncology"},{"focus":"New Drug Studies"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4131&type=small&showNoImage","displayName":"Branimir I. Sikic, M. D.","firstName":"Branimir","href":"http://med.stanford.edu/profiles/Branimir_Sikic","researchInterest":"Research Interests: cancer pharmacology, mechanisms of resistance to anticancer drugs, regulation and function of MDR1 and tubulin genes, clinical trials of modulation of drug resistance, general oncology, Phase I trials of new drugs, gene expression profiling of cancers"},{"lastName":"Fan Minogue","clinicalFocus":[],"appointments":[{"appointment":"MS, Dean's Office"}],"primaryAppointment":"MS, Dean's Office","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9608&type=small&showNoImage","displayName":"Hua Fan Minogue","firstName":"Hua","href":"http://med.stanford.edu/profiles/Hua_Fan Minogue","researchInterest":"Detecting protein-protein interactions during cell signaling using molecular imaging approaches, translating bench-side knowledges in cell biology and cancer biology into guidance for bedside therapy to benefit patient care and human health. \r\n  Recently,utilizing bioinformatics tools to understand cell signaling network in cancer development. Data mining and modeling for extraction of hidden relationship in cancer network. Whole genome sequencing, GWAS and PGx for individualized cancer therapy"},{"lastName":"Sahoo","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Pathology - Stem Cell Institute"}],"primaryAppointment":"Instructor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10888&type=small&showNoImage","displayName":"Debashis Sahoo","firstName":"Debashis","href":"http://med.stanford.edu/profiles/Debashis_Sahoo","researchInterest":""},{"lastName":"Wender","clinicalFocus":[],"appointments":[{"appointment":"Professor,Natural Sciences Cluster - Chemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Professor,Natural Sciences Cluster - Chemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6111&type=small&showNoImage","displayName":"Paul Wender","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Wender","researchInterest":""},{"lastName":"Lee","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stanford Cancer Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Stanford Cancer Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15254&type=small&showNoImage","displayName":"Cleo Lee","firstName":"Cleo Yi-Fang","href":"http://med.stanford.edu/profiles/Cleo Yi-Fang_Lee","researchInterest":"My current research interests are to study the biology of breast cancer stem cells (CSCs) and the functional role of genes involved in CSCs proliferation and self-renewal. Since CSCs are believed to be responsible for recurrent and metastatic breast cancer, the ultimate goal is to develope targeted therapies to specifically kill the CSCs subpopulation. Identification of genes involved in CSCs functions may lead to novel CSC targeted therapy."},{"lastName":"Gonzalez-Pena","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24539&type=small&showNoImage","displayName":"Veronica Gonzalez-Pena","firstName":"Veronica","href":"http://med.stanford.edu/profiles/Veronica_Gonzalez-Pena","researchInterest":""},{"lastName":"Winslow","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24603&type=small&showNoImage","displayName":"Monte Winslow","firstName":"Monte","href":"http://med.stanford.edu/profiles/Monte_Winslow","researchInterest":"Our laboratory uses genome-wide methods to uncover alterations that drive cancer progression and metastasis in genetically-engineered mouse models of human cancers. We combine cell-culture based mechanistic studies with our ability to alter pathways of interest during tumor progression in vivo to better understand each step of metastatic spread and to uncover the therapeutic vulnerabilities of advanced cancer cells."},{"lastName":"Brown","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4536&type=small&showNoImage","displayName":"Martin Brown","firstName":"Martin","href":"http://med.stanford.edu/profiles/Martin_Brown","researchInterest":"We seek to understand the mechanisms responsible for the resistance of cancers to treatment and to develop strategies to overcome these resistances. We are using molecular and cellular techniques and mouse models to potentiate the activity of radiation on tumors by inhibiting the bone marrow rescue of the tumor vasculature following therapy."},{"lastName":"Nair","clinicalFocus":[{"focus":"Pulmonary Disease"},{"focus":"Lung Cancer"},{"focus":"Solitary Pulmonary Nodule"},{"focus":"Intensive Care of the Medical Patient"}],"appointments":[{"appointment":"Instructor,Medicine - Pulmonary & Critical Care Medicine"}],"primaryAppointment":"Instructor,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13614&type=small&showNoImage","displayName":"Viswam S. Nair","firstName":"Viswam","href":"http://med.stanford.edu/profiles/Viswam_Nair","researchInterest":"\u0095 Molecular determinants of FDG-PET using non-invasive methods\r\n\u0095 Quantitative imaging of glucose metabolism in malignant nodules\r\n\u0095 Metabolic parameters of lung disease using FDG-PET\r\n\u0095 Circulating biomarker and clinical data database development for early detection of lung cancer"},{"lastName":"Dill","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8061&type=small&showNoImage","displayName":"David Dill","firstName":"David","href":"http://med.stanford.edu/profiles/David_Dill","researchInterest":""},{"lastName":"Tibshirani","clinicalFocus":[],"appointments":[{"appointment":"Professor,Health Research & Policy - Biostatistics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Natural Sciences Cluster - Statistics"}],"primaryAppointment":"Professor,Health Research & Policy - Biostatistics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4688&type=small&showNoImage","displayName":"Robert Tibshirani","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Tibshirani","researchInterest":"My research is in applied statistics and biostatistics. I specialize in \u000bcomputer-intensive methods for regression and classification, bootstrap, cross-validation\u000band statistical inference, and signal and image analysis for medical diagnosis."},{"lastName":"Arber","clinicalFocus":[{"focus":"Anatomic/Clinical Pathology"},{"focus":"Hematopathology"},{"focus":"Pathology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3925&type=small&showNoImage","displayName":"Daniel A. Arber, M.D.","firstName":"Daniel","href":"http://med.stanford.edu/profiles/Daniel_Arber","researchInterest":"I study molecular genetic and immunophenotypic changes in human hematopoietic neoplasms. These include acute and chronic leukemias, lymphoma, and splenic tumors."},{"lastName":"Chung","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Obstetrics & Gynecology"}],"primaryAppointment":"Basic Life Science Research Associate,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10387&type=small&showNoImage","displayName":"Young Min Chung","firstName":"Young Min","href":"http://med.stanford.edu/profiles/Young Min_Chung","researchInterest":""},{"lastName":"Neal","clinicalFocus":[{"focus":"Thoracic Oncology"},{"focus":"Lung Cancer"},{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Oncology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19045&type=small&showNoImage","displayName":"Joel Neal, MD, PhD","firstName":"Joel","href":"http://med.stanford.edu/profiles/Joel_Neal","researchInterest":"Applying new technologies to the diagnosis, characterization, and treatment of non-small cell lung cancer."},{"lastName":"Boxer","clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4658&type=small&showNoImage","displayName":"Linda Boxer","firstName":"Linda","href":"http://med.stanford.edu/profiles/Linda_Boxer","researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells."},{"lastName":"Clarke","clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology (Cancer)"},{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7126&type=small&showNoImage","displayName":"Michael F. Clarke, M.D.","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Clarke","researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine.  In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory  focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa"},{"lastName":"Gambhir","clinicalFocus":[{"focus":"Nuclear Medicine"},{"focus":"Radiology"},{"focus":"PET Scan"}],"appointments":[{"appointment":"Professor,Radiology - Diagnostic Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Bioengineering"},{"appointment":"Professor (By courtesy),Materials Science and Engineering - Engineering Materials Science"}],"primaryAppointment":"Professor,Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3971&type=small&showNoImage","displayName":"Sanjiv Sam Gambhir, MD, PhD","firstName":"Sanjiv","href":"http://med.stanford.edu/profiles/Sanjiv_Gambhir","researchInterest":"My laboratory focuses on merging advances in molecular biology with those in biomedical imaging to advance the new field of molecular imaging. Methods to image gene expression in living subjects have been developed.  Newer approaches to image fundamental cellular events with optical and radiolabeled probes are under active investigation. These imaging approaches are expected to have a fundamental impact in the study of cancer biology,  as well as in molecular therapeutics including gene therapy"},{"lastName":"Wakelee","clinicalFocus":[{"focus":"Lung Cancer - Medical Oncology"},{"focus":"Investigational Therapeutics"},{"focus":"Medical Oncology"},{"focus":"thymoma"},{"focus":"Mesothelioma "},{"focus":"thymic carcinoma"},{"focus":"Thoracic Cancers - Medical Oncology"},{"focus":"Mesothelioma - Medical Oncology"},{"focus":"Oncology (Cancer)"},{"focus":"Thoracic Cancers"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Oncology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor - Med Center Line,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6058&type=small&showNoImage","displayName":"Heather Wakelee","firstName":"Heather","href":"http://med.stanford.edu/profiles/Heather_Wakelee","researchInterest":"Dr. Wakelee's research is focused on clinical trials in patients with lung cancer and other thoracic malignancies such as thymoma and thymic carcinoma.  She also works with novel agents for all malignancies as part of the developmental therapeutics group of the cancer center.  Other interests include translation projects in thoracic malignancies and collaborations with population scientists regarding lung cancer questions."},{"lastName":"Das","clinicalFocus":[{"focus":"Thoracic Oncology"},{"focus":"Medical Oncology"}],"appointments":[],"imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=25011&type=small&showNoImage","displayName":"Millie Das","firstName":"Millie","href":"http://med.stanford.edu/profiles/Millie_Das","researchInterest":""},{"lastName":"O'Gorman","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18089&type=small&showNoImage","displayName":"William O'Gorman","firstName":"William","href":"http://med.stanford.edu/profiles/William_O'Gorman","researchInterest":""}]}