{"result":[{"lastName":"Aasi","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Mohs Surgery"},{"focus":"Dermatological Surgery"},{"focus":"Laser Surgery"},{"focus":"Skin oncology in transplant patients"},{"focus":"Melanoma and Skin Cancer"}],"appointments":[{"appointment":"Clinical Associate Professor,Dermatology"}],"primaryAppointment":"Clinical Associate Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24596&type=small&showNoImage","displayName":"Sumaira Aasi","firstName":"Sumaira","href":"http://med.stanford.edu/profiles/Sumaira_Aasi","researchInterest":"High risk squamous cell carcinoma; frozen histopathology; reconstructive surgery."},{"lastName":"Mochly-Rosen","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4256&type=small&showNoImage","displayName":"Daria Mochly-Rosen","firstName":"Daria","href":"http://med.stanford.edu/profiles/Daria_Mochly-Rosen","researchInterest":"Two areas:  1. Using rationally-designed peptide inhibitors to study protein-protein interactions in cell signaling.  We focus on protein kinase C (PKC)-mediated signal transduction and on mitochondrial dynamics in several disease models. 2. Using small molecules (identified in a high throughput screens and synthetic chemistry) as activators and inhibitors of aldehyde dehydrogenases, a family of detoxifying enzymes, we study their involvement  in normal cells and in models of human diseases."},{"lastName":"Fiorentino","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Autoimmune Diseases"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Medicine - Immunology & Rheumatology"}],"primaryAppointment":"Associate Professor - Med Center Line,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4719&type=small&showNoImage","displayName":"David Fiorentino, MD, PhD","firstName":"David","href":"http://med.stanford.edu/profiles/David_Fiorentino","researchInterest":"I am interested in all types of immune-mediated skin disease, with a focus on psoriasis and rheumatic skin disease.  I co-direct a multi-disciplinary clinic dedicated to the care of patients with rheumatic skin diseases, such as lupus erythematosus, vasculitis, dermatyositis and scleroderma.  I conduct multiple clinical trials and I participate in translational research with tissues obtained from a prospective cohort of patients with scleroderma, lupus, and dermatomyositis."},{"lastName":"Kim","clinicalFocus":[{"focus":"Cancer- cutaneous oncology"},{"focus":"Melanocytic neoplasia"},{"focus":"Dermatopathology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Pathology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Assistant Professor - Med Center Line,Dermatology"}],"primaryAppointment":"Assistant Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8622&type=small&showNoImage","displayName":"Jinah Kim","firstName":"Jinah","href":"http://med.stanford.edu/profiles/Jinah_Kim","researchInterest":""},{"lastName":"Cartwright","clinicalFocus":[{"focus":"Gastroenterology"},{"focus":"Inflammatory Bowel Diseases"}],"appointments":[{"appointment":"Professor,Medicine - Gastroenterology & Hepatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Gastroenterology & Hepatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4183&type=small&showNoImage","displayName":"Chris Cartwright, MD","firstName":"Christine","href":"http://med.stanford.edu/profiles/Christine_Cartwright","researchInterest":"Molecular mechanisms of intestinal cell growth control; function and regulation of the Src family of tyrosine kinases in normal cells, and their deregulation in cancer cells."},{"lastName":"Negrin","clinicalFocus":[{"focus":"Blood and Marrow Transplantation"},{"focus":"Hematology"}],"appointments":[{"appointment":"Professor,Medicine - Blood & Marrow Transplantation"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Blood & Marrow Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4138&type=small&showNoImage","displayName":"Robert Negrin","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Negrin","researchInterest":"Our labaratory focuses on the study of immune recognition by T and NK cells with special emphasis on graft vs host disease and graft vs tumor reactions. We utilize both murine and human systems in an effort to enhance graft vs tumor reactions while controlling graft vs host disease. We have developed bioluminescence models in collaboration with the Contag laboratory to study the trafficking of immune effector cells with a special emphasis on NK, T and regulatory T cells."},{"lastName":"Genovese","clinicalFocus":[{"focus":"Rheumatology"},{"focus":"Immunology/Rheumatology"}],"appointments":[{"appointment":"Professor - Med Center Line,Medicine - Immunology & Rheumatology"}],"primaryAppointment":"Professor - Med Center Line,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4195&type=small&showNoImage","displayName":"Mark Genovese","firstName":"Mark","href":"http://med.stanford.edu/profiles/Mark_Genovese","researchInterest":"Clinical trials and interventions in the rheumatic diseases including Rheumatoid Arthritis,Systemic Lupus Erythematosus, Systemic Sclerosis, Osteoarthritis."},{"lastName":"Chan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Medical fellow, Medicine"}],"primaryAppointment":"Postdoctoral Medical fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23335&type=small&showNoImage","displayName":"Steven Chan","firstName":"Steven","href":"http://med.stanford.edu/profiles/Steven_Chan","researchInterest":""},{"lastName":"Roth","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4175&type=small&showNoImage","displayName":"Richard Roth","firstName":"Richard","href":"http://med.stanford.edu/profiles/Richard_Roth","researchInterest":"Insulin is one of the primary regulators of rapid anabolic responses in the body. Defects in the synthesis and/or ability of cells to respond to insulin results in the condition known as diabetes mellitus. To better design methods of treatment for this disorder, we have been focusing our research on how insulin elicits its various biological responses."},{"lastName":"Arai","clinicalFocus":[{"focus":"Blood and Marrow Transplantation"},{"focus":"Hematology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Blood & Marrow Transplantation"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Blood & Marrow Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6161&type=small&showNoImage","displayName":"Sally Arai","firstName":"Sally","href":"http://med.stanford.edu/profiles/Sally_Arai","researchInterest":"Research interest in utilizing post-transplant adoptive cellular immunotherapy to reduce GVHD and relapse in patients with high risk hematologic malignancies."},{"lastName":"Johnston","clinicalFocus":[{"focus":"Blood and Marrow Transplantation"},{"focus":"Hematology"},{"focus":"Graft-Versus-Host Disease"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Blood & Marrow Transplantation"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor - Med Center Line,Medicine - Blood & Marrow Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4572&type=small&showNoImage","displayName":"Laura Johnston","firstName":"Laura","href":"http://med.stanford.edu/profiles/Laura_Johnston","researchInterest":"Clinical research in allogeneic and autologous hematopoietic cell transplantation (HCT), more specifically, allogeneic transplantation and graft versus host disease. Exploring methods of improving prevention and treatment of GVHD as well as the long term follow-up and/or quality of life of affected patients."},{"lastName":"Kopito","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6227&type=small&showNoImage","displayName":"Ron Kopito","firstName":"Ron","href":"http://med.stanford.edu/profiles/Ron_Kopito","researchInterest":"Our research is concerned with elucidating the basic cellular molecular mechanisms that underly the recognition and destruction of misfolded or mis-assembled proteins in eukaryotic cells.  We study dominatly inherited human neurodegenerative disorders like Alzheimer's, Huntington's or Parkinson's diseases that are caused by the failure of this system to effectively recognize and destroy such proteins."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Buecker","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemical and Systems Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20923&type=small&showNoImage","displayName":"Christa Buecker","firstName":"Christa","href":"http://med.stanford.edu/profiles/Christa_Buecker","researchInterest":""},{"lastName":"Sundram","clinicalFocus":[{"focus":"Pathology"},{"focus":"Anatomic/Clinical Pathology"},{"focus":"Dermatopathology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Pathology"},{"appointment":"Assistant Professor - Med Center Line,Dermatology"}],"primaryAppointment":"Assistant Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4058&type=small&showNoImage","displayName":"Uma N. Sundram, MD, PhD","firstName":"Uma","href":"http://med.stanford.edu/profiles/Uma_Sundram","researchInterest":"Broad study of extramedullary myeloid tumors; Characterization of CD30+ lymphoproliferative disorders and pathogenesis; Mutational analysis of CD30+ lymphoproliferative disorders; Characterization of cutaneous mast cell disease and distinction from systemic mastocytosis; Comparison of systemic and cutaneous B cell lymphomas by immunohistochemical profiles and the use of tissue microarrays; microRNA studies of cutaneous lymphomas"},{"lastName":"Plews","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=21065&type=small&showNoImage","displayName":"Jordan Plews","firstName":"Jordan","href":"http://med.stanford.edu/profiles/Jordan_Plews","researchInterest":""},{"lastName":"Lan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13653&type=small&showNoImage","displayName":"Feng Lan","firstName":"Feng","href":"http://med.stanford.edu/profiles/Feng_Lan","researchInterest":""},{"lastName":"Maecker","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Microbiology & Immunology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor (Research),Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=25058&type=small&showNoImage","displayName":"Holden Maecker","firstName":"Holden","href":"http://med.stanford.edu/profiles/Holden_Maecker","researchInterest":"I'm interested in immune monitoring of T cell responses to chronic pathogens such as CMV, and the correlation of T cell response signatures with disease protection."},{"lastName":"Natkunam","clinicalFocus":[{"focus":"Hematopathology"},{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic Pathology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5929&type=small&showNoImage","displayName":"Yasodha Natkunam, M.D., Ph.D","firstName":"Yasodha","href":"http://med.stanford.edu/profiles/Yasodha_Natkunam","researchInterest":"My research interests focus on the identification and characterization of markers of diagnostic and prognostic importance in hematolymphoid neoplasia."},{"lastName":"Benjamin","clinicalFocus":[{"focus":"Blood and Marrow Transplantation"},{"focus":"Internal Medicine"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Blood & Marrow Transplantation"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Blood & Marrow Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8612&type=small&showNoImage","displayName":"Jonathan Benjamin","firstName":"Jonathan","href":"http://med.stanford.edu/profiles/Jonathan_Benjamin","researchInterest":"My research interests adoptive transfer of defined subsets of lymphocytes for the treatment of hematologic malignancies. I have a specific interest in the treatment of Myelodysplastic Syndromes with non-myeloablative and reduced intensity transplant conditioning regimens."},{"lastName":"Nakasone","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=36670&type=small&showNoImage","displayName":"Hideki Nakasone","firstName":"Hideki","href":"http://med.stanford.edu/profiles/Hideki_Nakasone","researchInterest":""},{"lastName":"Krensky","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Pediatrics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4484&type=small&showNoImage","displayName":"Alan M. Krensky, M.D.","firstName":"Alan","href":"http://med.stanford.edu/profiles/Alan_Krensky","researchInterest":"Mechanisms and therapies for infection, cancer, autoimmunity and transplantation."},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7143&type=small&showNoImage","displayName":"Albert J. Wong, M.D.","firstName":"Albert","href":"http://med.stanford.edu/profiles/Albert_Wong","researchInterest":"Our goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring  mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective."}]}