{"result":[{"lastName":"Zhao","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=29446&type=small&showNoImage","displayName":"Minglei Zhao","firstName":"Minglei","href":"http://med.stanford.edu/profiles/Minglei_Zhao","researchInterest":""},{"lastName":"Winans","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Dean's Office"}],"primaryAppointment":"Ph.D., Dean's Office","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20077&type=small&showNoImage","displayName":"Amy Winans","firstName":"Amy","href":"http://med.stanford.edu/profiles/Amy_Winans","researchInterest":""},{"lastName":"Levitt","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Computer Science"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4494&type=small&showNoImage","displayName":"Michael Levitt","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Levitt","researchInterest":"having pioneered, we (a) predict folding of a polypeptide and RNA chains into a unique native-structure, we (b) model protein structure using the well-established paradigms that similar protein sequences imply similar three-dimensional structures, and (c) we are focusing on mesoscale modeling of large macromolecular complexes such as RNA polymerase and the mammalian chaperonin."},{"lastName":"Doniach","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8062&type=small&showNoImage","displayName":"Sebastian Doniach","firstName":"Sebastian","href":"http://med.stanford.edu/profiles/Sebastian_Doniach","researchInterest":""},{"lastName":"Worfolk","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemical Engineering"}],"primaryAppointment":"Postdoctoral Research fellow, Chemical Engineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=38382&type=small&showNoImage","displayName":"Brian Worfolk","firstName":"Brian","href":"http://med.stanford.edu/profiles/Brian_Worfolk","researchInterest":""},{"lastName":"Tong","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23061&type=small&showNoImage","displayName":"Ling Tong","firstName":"Ling","href":"http://med.stanford.edu/profiles/Ling_Tong","researchInterest":"Study of biological mechanism and dynamics  (especially Tumor microenvironemtn) by intravital imaging; \r\nDevelopment of nanomedicines for diagnosis and therapy;\r\nUnderstanding of nano-bio interaction"},{"lastName":"Frank","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8065&type=small&showNoImage","displayName":"Curtis Frank","firstName":"Curtis","href":"http://med.stanford.edu/profiles/Curtis_Frank","researchInterest":""},{"lastName":"Nag","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23884&type=small&showNoImage","displayName":"Suman Nag","firstName":"Suman","href":"http://med.stanford.edu/profiles/Suman_Nag","researchInterest":"Mutations in the beta-cardiac myosin (a molecular motor) cause disastrous effects by manifestation of hypertrophic and dilated cardiomyopathy, a leading cause of cardiac death. We hypothesize that the such mutations cause fundamental mechanistic changes in the motor which in turn affect the efficiency of the motor in several ways. My current research involves single molecule enzyme kinetics and force measurements to link intrinsic changes in motor function to the various clinical outcomes."},{"lastName":"Solomon","clinicalFocus":[],"appointments":[{"appointment":"Professor,Natural Sciences Cluster - Chemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Photon Science Directorate"}],"primaryAppointment":"Professor,Natural Sciences Cluster - Chemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8081&type=small&showNoImage","displayName":"Edward I. Solomon","firstName":"Edward","href":"http://med.stanford.edu/profiles/Edward_Solomon","researchInterest":"Professor Solomon\u0092s research is in the fields of Physical-Inorganic, Bioinorganic, and Theoretical-Inorganic Chemistry. His focus is on spectroscopic elucidation of the electronic structure of transition metal complexes and its contribution to reactivity.  He has made significant contributions to our understanding of metal sites involved in electron transfer, copper sites involved in O2 binding, activation and reduction to water, and in structure/function correlations over non-heme iron enzymes."},{"lastName":"Shukla","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23493&type=small&showNoImage","displayName":"Diwakar Shukla","firstName":"Diwakar","href":"http://med.stanford.edu/profiles/Diwakar_Shukla","researchInterest":""},{"lastName":"Yan","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Hematology"}],"primaryAppointment":"Instructor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13412&type=small&showNoImage","displayName":"Kelley Yan","firstName":"Kelley","href":"http://med.stanford.edu/profiles/Kelley_Yan","researchInterest":""},{"lastName":"Liu","clinicalFocus":[],"appointments":[{"appointment":"Engr Res Assoc,Genetics"}],"primaryAppointment":"Engr Res Assoc,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9027&type=small&showNoImage","displayName":"Tianyun Liu","firstName":"Tianyun","href":"http://med.stanford.edu/profiles/Tianyun_Liu","researchInterest":""},{"lastName":"Baldwin","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Biochemistry"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6816&type=small&showNoImage","displayName":"Robert Baldwin","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Baldwin","researchInterest":"I closed my laboratory when I retired in 1998.  I continue to do research, chiefly in collaboration with Franc Avbelj, on problems of protein folding energetics, especially peptide backbone solvation,  and to write reviews."},{"lastName":"Gherardini","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35679&type=small&showNoImage","displayName":"Pier Federico Gherardini","firstName":"Pier Federico","href":"http://med.stanford.edu/profiles/Pier Federico_Gherardini","researchInterest":""},{"lastName":"Ali","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiation Oncology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiation Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15800&type=small&showNoImage","displayName":"Rehan Ali","firstName":"Rehan","href":"http://med.stanford.edu/profiles/Rehan_Ali","researchInterest":"My research focus is on developing techniques to better predict the response of tumors to radiotherapy. Through a combination of experimental work (preclinical molecular imaging) and computational approaches (image processing and mathematical modeling), I aim to improve our ability to (a) infer biologically relevant information from imaging data, and b) reliably predict whether / how specific tumor regions are resistant to radiation therapy."},{"lastName":"McKay","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","displayName":"David B. McKay","firstName":"David","href":"http://med.stanford.edu/profiles/David_McKay","researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules."},{"lastName":"Saggu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Natural Sciences Cluster"}],"primaryAppointment":"Postdoctoral Research fellow, Natural Sciences Cluster","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=16850&type=small&showNoImage","displayName":"Miguel Saggu","firstName":"Miguel","href":"http://med.stanford.edu/profiles/Miguel_Saggu","researchInterest":""},{"lastName":"Gofman","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=34497&type=small&showNoImage","displayName":"Yana Gofman","firstName":"Yana","href":"http://med.stanford.edu/profiles/Yana_Gofman","researchInterest":""},{"lastName":"Graef","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7247&type=small&showNoImage","displayName":"Isabella Graef","firstName":"Isabella","href":"http://med.stanford.edu/profiles/Isabella_Graef","researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases."},{"lastName":"Jokerst","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=14145&type=small&showNoImage","displayName":"Jesse Jokerst","firstName":"Jesse","href":"http://med.stanford.edu/profiles/Jesse_Jokerst","researchInterest":""},{"lastName":"Chu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15846&type=small&showNoImage","displayName":"Matthew Chu","firstName":"Ling Hon","href":"http://med.stanford.edu/profiles/Ling Hon_Chu","researchInterest":""},{"lastName":"Zhu","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35767&type=small&showNoImage","displayName":"Alex Zhu","firstName":"Gefei","href":"http://med.stanford.edu/profiles/Gefei_Zhu","researchInterest":""},{"lastName":"Mallick","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology"}],"primaryAppointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18938&type=small&showNoImage","displayName":"Parag Mallick","firstName":"Parag","href":"http://med.stanford.edu/profiles/Parag_Mallick","researchInterest":"Our research centers on developing and applying  proteomics and systems biology approaches to quantitatively describe organisms' physiologic states towards the goal of enabling personalized, predictive medicine.  As part of this effort we are trying to characterize the diverse states of cells (using proteomic and transcriptomic methods) and how signals describing those states are propagated from molecular and cellular length scales to tumor and organismic length scales."},{"lastName":"Frydman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6222&type=small&showNoImage","displayName":"Judith Frydman","firstName":"Judith","href":"http://med.stanford.edu/profiles/Judith_Frydman","researchInterest":"The long term goal  of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether  reengineering chaperone networks can provide therapeutic strategies."}]}