{"result":[{"lastName":"Nachury","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8391&type=small&showNoImage","displayName":"Maxence Nachury","firstName":"Maxence","href":"http://med.stanford.edu/profiles/Maxence_Nachury","researchInterest":"We study the primary cilium, a once-obscure cellular organelle recently \"re-discovered\" for its role in a number of signaling pathways. Defects in cilium biogenesis lead to a variety of hereditary disorders characterized by retinal degeneration, kidney cysts and obesity. Our goal is  to characterize these disorders at the molecular and cellular levels to gain insight into the basic mechanisms of primary cilium biogenesis and to discover novel ciliary signaling pathways."},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Chemical and Systems Biology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor,Developmental Biology"},{"appointment":"Associate Professor (By courtesy),Natural Sciences Cluster - Chemistry Department"}],"primaryAppointment":"Associate Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3938&type=small&showNoImage","displayName":"James K. Chen","firstName":"James","href":"http://med.stanford.edu/profiles/James_Chen","researchInterest":"Our laboratory combines synthetic chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis.  We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development."},{"lastName":"Breslow","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19226&type=small&showNoImage","displayName":"David Breslow","firstName":"David","href":"http://med.stanford.edu/profiles/David_Breslow","researchInterest":""},{"lastName":"Egeler","clinicalFocus":[],"appointments":[{"appointment":"Spark Program Assistant,Dean's Office - Senior Associate Dean for Research"},{"appointment":"Admin Services Administrator,Dean's Office - Senior Associate Dean for Research"}],"primaryAppointment":"Spark Program Assistant,Dean's Office - Senior Associate Dean for Research","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19534&type=small&showNoImage","displayName":"Emily Egeler","firstName":"Emily","href":"http://med.stanford.edu/profiles/Emily_Egeler","researchInterest":"Understanding how cells sense and target misfolded proteins for degradation, with the goal of identifying more quality control mechanisms in the cell."},{"lastName":"Atwood","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Dermatology"}],"primaryAppointment":"Postdoctoral Research fellow, Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10356&type=small&showNoImage","displayName":"Scott Atwood","firstName":"Scott","href":"http://med.stanford.edu/profiles/Scott_Atwood","researchInterest":"My research focus is on protein kinase regulation of primary cilia-mediated signaling, skin and hair follicle development, and epithelial tumor progression. My work has discovered novel roles of kinases in neural stem cell self-renewal and differentiation, primary cilia structure and signaling, hair follicle cycling, and basal cell carcinoma progression. How kinases achieve these diverse functions are an ongoing area of investigation."},{"lastName":"Woo","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Dermatology"}],"primaryAppointment":"Basic Life Science Research Associate,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9651&type=small&showNoImage","displayName":"Wei-Meng Woo","firstName":"Wei","href":"http://med.stanford.edu/profiles/Wei_Woo","researchInterest":""},{"lastName":"Rack","clinicalFocus":[],"appointments":[{"appointment":"Temp - Non-Exempt,Chemical and Systems Biology"}],"primaryAppointment":"Temp - Non-Exempt,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19586&type=small&showNoImage","displayName":"Paul G. Rack","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Rack","researchInterest":""},{"lastName":"Jacobson","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=34821&type=small&showNoImage","displayName":"Catherine Jacobson","firstName":"Catherine","href":"http://med.stanford.edu/profiles/Catherine_Jacobson","researchInterest":""},{"lastName":"Beachy","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Developmental Biology"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7655&type=small&showNoImage","displayName":"Philip Beachy","firstName":"Philip","href":"http://med.stanford.edu/profiles/Philip_Beachy","researchInterest":"Function of Hedgehog proteins and other extracellular signals in morphogenesis (pattern formation), in injury repair and regeneration (pattern maintenance). We study how the distribution of such signals is regulated in tissues, how cells perceive and respond to distinct concentrations of signals, and how such signaling pathways arose in evolution. We also study the normal roles of such signals in stem-cell physiology and their abnormal roles in the formation and expansion of cancer stem cells."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Shrewsbury","clinicalFocus":[],"appointments":[{"appointment":"Service Centers & Special Projects Manager,Dean's Office - Finance & Administration, Controller's Office"},{"appointment":"Admin Services Administrator,Dean's Office - Finance & Administration, Controller's Office"}],"primaryAppointment":"Service Centers & Special Projects Manager,Dean's Office - Finance & Administration, Controller's Office","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=28041&type=small&showNoImage","displayName":"Adeline  Shrewsbury","firstName":"Mary","href":"http://med.stanford.edu/profiles/Mary_Shrewsbury","researchInterest":""},{"lastName":"Kosinski","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=17415&type=small&showNoImage","displayName":"Cynthia Kosinski","firstName":"Cynthia","href":"http://med.stanford.edu/profiles/Cynthia_Kosinski","researchInterest":""},{"lastName":"Teruel","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=14171&type=small&showNoImage","displayName":"Mary Frances Nunez Teruel","firstName":"Mary","href":"http://med.stanford.edu/profiles/Mary_Teruel","researchInterest":"The Teruel Lab uses a combination of engineering and biological approaches including high-throughput screening of RNAi and DNA construct libraries, targeted mass spectrometry, live-cell fluorescence microscopy, and bioinformatics to investigate the systems biology of cell differentiation and cell signaling with particular focus on uncovering the molecular mechanisms underlying insulin resistance, diabetes, and obesity."},{"lastName":"Weissman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology - Stem Cell Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4605&type=small&showNoImage","displayName":"Irving Weissman","firstName":"Irving","href":"http://med.stanford.edu/profiles/Irving_Weissman","researchInterest":"Stem cell and cancer stem cell biology; development of T and B lymphocytes; cell-surface receptors for oncornaviruses in leukemia. Hematopoietic stem cells; Lymphocyte homing, lymphoma invasiveness and metastasis."},{"lastName":"Khavari","clinicalFocus":[{"focus":"Dermatology"},{"focus":"General Dermatology"}],"appointments":[{"appointment":"Professor,Dermatology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4683&type=small&showNoImage","displayName":"Paul A. Khavari, MD, PhD","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Khavari","researchInterest":"We work in epithelial tissue as a model system to study stem cell biology, cancer and new molecular therapeutics. Epithelia cover external and internal body surfaces and undergo constant self-renewal while responding to diverse environmental stimuli. Epithelial homeostasis precisely balances stem cell-sustained proliferation and differentiation-associated cell death, a balance which is lost in many human diseases, including cancer, 90% of which arise in epithelial tissues."},{"lastName":"Reuter","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15072&type=small&showNoImage","displayName":"Jason Reuter","firstName":"Jason","href":"http://med.stanford.edu/profiles/Jason_Reuter","researchInterest":""}]}