Peter P. Lee
Publication Details
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Diversity and recognition efficiency of T cell responses to cancer.
PLoS Med. 2004; (2): e28
Melanoma patients vaccinated with tumor-associated antigens frequently develop measurable peptide-specific CD8+ T cell responses; however, such responses often do not confer clinical benefit. Understanding why vaccine-elicited responses are beneficial in some patients but not in others will be important to improve targeted cancer immunotherapies.
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