Amato J. Giaccia
Publication Details
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Energy regulation: HIF MXIes it up with the C-MYC powerhouse.
Dev Cell. 2007; (6): 845-6
The phenomenon of aerobic glycolysis observed in cancer cells has remained unexplained. In the May 2007 issue of Cancer Cell, Zhang and colleagues determine that the hypoxia-inducible factor family of transcriptional factors regulate mitochondrial biogenesis through inhibition of C-MYC.
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