Cancer Institute A national cancer institute
designated cancer center

Xiaoyuan (Shawn) Chen

Publication Details

  • Evaluation of biodistribution and anti-tumor effect of a dimeric RGD peptide-paclitaxel conjugate in mice with breast cancer.

    Cao Q, Li ZB, Chen K, Wu Z, He L, Neamati N, Chen X. Eur J Nucl Med Mol Imaging. 2008; 35 (8): 1489-98

    Targeting drugs to receptors involved in tumor angiogenesis has been demonstrated as a novel and promising approach to improve cancer treatment. In this study, we evaluated the anti-tumor efficacy of a dimeric RGD peptide-paclitaxel conjugate (RGD2-PTX) in an orthotopic MDA-MB-435 breast cancer model.

    PubMedID: 18373091

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