Roeland Nusse
Publication Details
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Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells.
Gastroenterology. 2007; (5): 1579-91
Oval cells are postnatal hepatic progenitors with high proliferative potential and bipotent differentiation ability to become hepatocytes and cholangiocytes. Because Wnt/beta-catenin signaling is a known regulatory pathway for liver development and regeneration, we studied the role of Wnt signaling in oval cells using a mouse model of chronic liver injury.
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