John Ioannidis
Publication Details
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Predictive ability of DNA microarrays for cancer outcomes and correlates: an empirical assessment.
Lancet. 2003; (9394): 1439-44
DNA microarrays are being used for many applications, including the prediction of cancer outcomes by simultaneous analysis of the expression of thousands of genes. We systematically assessed the predictive performance of this method for major clinical outcomes (death, metastasis, recurrence, response to therapy) and the correlation of gene profiling with other clinicopathological correlates of malignant disorders.
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