Cancer Institute A national cancer institute
designated cancer center

Stanley N. Cohen, MD

Publication Details

  • Transposition protein of Tn3: identification and characterisation of an essential repressor-controlled gene product.

    Chou J, Lemaux PG, Casadaban MJ, Cohen SN. Nature. 1979 Dec 20-27; 282 (5741): 801-6

    Fusions that bring lac gene expression under the control of transcriptional and translational signals within the Tn3 element have been used to identify and characterise a Tn3-encoded 'transposase' (Tnp) peptide of MW 100,000 essential for transposition. The gene specifying this product is regulated by the Tn3 repressor protein and is part of a bidirectional genetic unit that includes the repressor gene.

    PubMedID: 390402

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