Cancer Institute A national cancer institute
designated cancer center

Stanley N. Cohen, MD

Publication Details

  • Effect of DNA sequences adjacent to the termini of Tn3 on sequential translocation.

    Tu CP, Cohen SN. Mol Gen Genet. 1980; 177 (4): 597-601

    Insertion of Tn3 generates a five base pair repeat of a nucleotide sequence indigenous to the recipient genome. Tn3 promoted deletions extend precisely from the Tn3 terminus and remove one of the 5 base pair repeats while not affecting the ability of Tn3 to subsequently undergo translocation. A direct repeat of a 10 bp sequence located in the Tn3 termini occurs internally within Tn3 and may affect the orientation of insertion.

    PubMedID: 6247609

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