David K. Stevenson, M.D.
Publication Details
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Continuous parenteral infusion of vitamin E pharmacokinetics and bilirubin production in premature neonates.
Ann N Y Acad Sci. 1989: 352-7
We conclude that 5 mg/kg of vitamin E, administered intra-arterially as an 8-hour continuous infusion, significantly and predictably raises serum vitamin E levels into the supraphysiologic range with no apparent side effects. In a group of premature infants whose initial serum vitamin E levels were generally greater than or equal to 0.5 mg/dL, no decrease in bilirubin production was observed. Thus, vitamin E deficiency probably does not play a prominent role in jaundice of prematurity.
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