Cancer Institute A national cancer institute
designated cancer center

Sanjiv Sam Gambhir, MD, PhD

Publication Details

  • Visualization of telomerase reverse transcriptase (hTERT) promoter activity using a trimodality fusion reporter construct.

    Padmanabhan P, Otero J, Ray P, Paulmurugan R, Hoffman AR, Gambhir SS, Biswal S, Ulaner GA. J Nucl Med. 2006; 47 (2): 270-7

    Our goal was to noninvasively measure chemotherapy-induced changes in the expression of critical tumor growth genes. To achieve this goal, we used radionuclide and optical methods to measure changes in human telomerase reverse transcriptase (hTERT) gene expression in tumor cells before and after 5-fluorouracil treatment.

    PubMedID: 16455633

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