James K. Chen
Publication Details
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Cyclic caged morpholinos: conformationally gated probes of embryonic gene function.
Angew Chem Int Ed Engl. 2012; (28): 6908-11
Feeling a bit cagey: morpholino-based antisense reagents have been caged through oligonucleotide cyclization, enabling photocontrol of gene expression in zebrafish embryos and larvae. Using these reagents, the timing of exocrine cell fate commitment in the developing pancreas has been examined.
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