Denise M. Monack
Publications
- Policing the cytosol--bacterial-sensing inflammasome receptors and pathways. Curr Opin Immunol. 2013; (1): 34-9
- The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus. Cell. 2013; (4): 743-54
- Innate immune response to Salmonella typhimurium, a model enteric pathogen. Gut Microbes. 2012 Mar-Apr; (2): 62-70
- Caspase-1 activity is required to bypass macrophage apoptosis upon Salmonella infection. Nat Chem Biol. 2012; (9): 745-7
- Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1. Nature. 2012; (7419): 288-91
- Delayed activation of host innate immune pathways in streptozotocin-induced diabetic hosts leads to more severe disease during infection with Burkholderia pseudomallei. Immunology. 2012; (4): 312-32
- Francisella infection triggers activation of the AIM2 inflammasome in murine dendritic cells. Cell Microbiol. 2012; (1): 71-80
- Salmonella persistence and transmission strategies. Curr Opin Microbiol. 2012; (1): 100-7
- Salmonella's long-term relationship with its host. FEMS Microbiol Rev. 2012; (3): 600-15
- Shedding light on Salmonella carriers. Trends Microbiol. 2012; (7): 320-7
- At home with hostility: How do pathogenic bacteria evade mammalian immune surveillance to establish persistent infection? F1000 Biol Rep. 2011: 1
- Elevated AIM2-mediated pyroptosis triggered by hypercytotoxic Francisella mutant strains is attributed to increased intracellular bacteriolysis. Cell Microbiol. 2011; (10): 1586-600
- Francisella tularensis Schu S4 O-antigen and capsule biosynthesis gene mutants induce early cell death in human macrophages. Infect Immun. 2011; (2): 581-94
- Immunology: recognition of a unique partner. Nature. 2011; (7366): 543-4
- Innate immune recognition of francisella tularensis: activation of type-I interferons and the inflammasome. Front Microbiol. 2011: 16
- Molecular mechanisms of inflammasome activation during microbial infections. Immunol Rev. 2011; (1): 174-90
- The two-component sensor kinase KdpD is required for Salmonella typhimurium colonization of Caenorhabditis elegans and survival in macrophages. Cell Microbiol. 2011; (10): 1618-37
- Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. Proc Natl Acad Sci U S A. 2010; (21): 9771-6
- Contributions of Francisella tularensis subsp. novicida chitinases and Sec secretion system to biofilm formation on chitin. Appl Environ Microbiol. 2010; (2): 596-608
- Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing. Cell Host Microbe. 2010; (6): 471-83
- Indoleamine 2,3-dioxygenase 1 is a lung-specific innate immune defense mechanism that inhibits growth of Francisella tularensis tryptophan auxotrophs. Infect Immun. 2010; (6): 2723-33
- Reciprocal analysis of Francisella novicida infections of a Drosophila melanogaster model reveal host-pathogen conflicts mediated by reactive oxygen and imd-regulated innate immune response. PLoS Pathog. 2010; (8): e1001065
- Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. J Exp Med. 2010; (8): 1745-55
- Two physically, functionally, and developmentally distinct peritoneal macrophage subsets. Proc Natl Acad Sci U S A. 2010; (6): 2568-73
- Type I IFN signaling constrains IL-17A/F secretion by gammadelta T cells during bacterial infections. J Immunol. 2010; (7): 3755-67
- Contribution of flagellin pattern recognition to intestinal inflammation during Salmonella enterica serotype typhimurium infection. Infect Immun. 2009; (5): 1904-16
- The Salmonella SPI2 effector SseI mediates long-term systemic infection by modulating host cell migration. PLoS Pathog. 2009; (11): e1000671
- Transcriptional response in the peripheral blood of patients infected with Salmonella enterica serovar Typhi. Proc Natl Acad Sci U S A. 2009; (52): 22433-8
- Host transmission of Salmonella enterica serovar Typhimurium is controlled by virulence factors and indigenous intestinal microbiota. Infect Immun. 2008; (1): 403-16
- Identification of fevR, a novel regulator of virulence gene expression in Francisella novicida. Infect Immun. 2008; (8): 3473-80
- The inflammasome: a key player in the inflammation triggered in response to bacterial pathogens. J Pediatr Gastroenterol Nutr. 2008: E14
- Activation of the inflammasome upon Francisella tularensis infection: interplay of innate immune pathways and virulence factors. Cell Microbiol. 2007; (11): 2543-51
- Francisella tularensis: activation of the inflammasome. Ann N Y Acad Sci. 2007: 219-37
- In vivo negative selection screen identifies genes required for Francisella virulence. Proc Natl Acad Sci U S A. 2007; (14): 6037-42
- Type I interferon signaling is required for activation of the inflammasome during Francisella infection. J Exp Med. 2007; (5): 987-94
- Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse. PLoS Pathog. 2006; (2): e11
- Identification of MglA-regulated genes reveals novel virulence factors in Francisella tularensis. Infect Immun. 2006; (12): 6642-55
- Mig-14 is an inner membrane-associated protein that promotes Salmonella typhimurium resistance to CRAMP, survival within activated macrophages and persistent infection. Mol Microbiol. 2005; (3): 954-72
- Persistent bacterial infections: the interface of the pathogen and the host immune system. Nat Rev Microbiol. 2004; (9): 747-65
- Salmonella typhimurium persists within macrophages in the mesenteric lymph nodes of chronically infected Nramp1+/+ mice and can be reactivated by IFNgamma neutralization. J Exp Med. 2004; (2): 231-41
- Modulation of virulence by two acidified nitrite-responsive loci of Salmonella enterica serovar Typhimurium. Infect Immun. 2003; (6): 3196-205
- virK, somA and rcsC are important for systemic Salmonella enterica serovar Typhimurium infection and cationic peptide resistance. Mol Microbiol. 2003; (2): 385-400
- Salmonella-induced macrophage death: the role of caspase-1 in death and inflammation. Microbes Infect. 2001 Nov-Dec; (14-15): 1201-12
- Actin-based motility is sufficient for bacterial membrane protrusion formation and host cell uptake. Cell Microbiol. 2001; (9): 633-47
- Salmonella pathogenicity island 2-dependent macrophage death is mediated in part by the host cysteine protease caspase-1. Cell Microbiol. 2001; (12): 825-37
- The making of a gradient: IcsA (VirG) polarity in Shigella flexneri. Mol Microbiol. 2001; (4): 861-72
- Apoptosis as a common bacterial virulence strategy. Int J Med Microbiol. 2000; (1): 7-13
- Salmonella exploits caspase-1 to colonize Peyer's patches in a murine typhoid model. J Exp Med. 2000; (2): 249-58
- Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival. Mol Microbiol. 1998; (1): 175-88
- Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of mice. J Exp Med. 1998; (11): 2127-37
- Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death. Proc Natl Acad Sci U S A. 1997; (19): 10385-90
- Salmonella typhimurium invasion induces apoptosis in infected macrophages. Proc Natl Acad Sci U S A. 1996; (18): 9833-8
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