Tim Stearns
Publications
- The Rilp-like proteins Rilpl1 and Rilpl2 regulate ciliary membrane content. Mol Biol Cell. 2013; (4): 453-64
- STED microscopy with optimized labeling density reveals 9-fold arrangement of a centriole protein. Biophys J. 2012; (12): 2926-35
- Supernumerary centrosomes nucleate extra cilia and compromise primary cilium signaling. Curr Biol. 2012; (17): 1628-34
- FOP is a centriolar satellite protein involved in ciliogenesis. PLoS One. 2013; (3): e58589
- The centriolar satellite proteins Cep72 and Cep290 interact and are required for recruitment of BBS proteins to the cilium. Mol Biol Cell. 2012; (17): 3322-35
- Transcriptional program of ciliated epithelial cells reveals new cilium and centrosome components and links to human disease. PLoS One. 2012; (12): e52166
- A crucial requirement for Hedgehog signaling in small cell lung cancer. Nat Med. 2011; (11): 1504-8
- Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation. Eukaryot Cell. 2011; (11): 1574-81
- The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries. Nat Cell Biol. 2011; (10): 1154-60
- Cep120 is asymmetrically localized to the daughter centriole and is essential for centriole assembly. J Cell Biol. 2010; (2): 331-46
- Cep152 interacts with Plk4 and is required for centriole duplication. J Cell Biol. 2010; (4): 721-9
- The life cycle of centrioles. Cold Spring Harb Symp Quant Biol. 2010: 425-31
- Centriole age underlies asynchronous primary cilium growth in mammalian cells. Curr Biol. 2009; (17): 1498-502
- Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components. PLoS One. 2009; (6): e5976
- Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells. Dev Cell. 2009; (3): 344-54
- Stem cells: A fateful age gap. Nature. 2009; (7266): 891-2
- Primary cilia: cellular sensors for the skeleton. Anat Rec (Hoboken). 2008; (9): 1074-8
- Microtubule-organizing centres: a re-evaluation. Nat Rev Mol Cell Biol. 2007; (2): 161-7
- Molecular characterization of centriole assembly in ciliated epithelial cells. J Cell Biol. 2007; (1): 31-42
- Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism. Proc Natl Acad Sci U S A. 2007; (33): 13325-30
- Controlling centrosome number: licenses and blocks. Curr Opin Cell Biol. 2006; (1): 74-8
- GCP-WD is a gamma-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation. Nat Cell Biol. 2006; (2): 137-47
- Mechanism limiting centrosome duplication to once per cell cycle. Nature. 2006; (7105): 947-51
- Insights into microtubule nucleation from the crystal structure of human gamma-tubulin. Nature. 2005; (7041): 523-7
- Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure. BMC Cell Biol. 2005; (1): 6
- Centrosome number is controlled by a centrosome-intrinsic block to reduplication. Nat Cell Biol. 2003; (6): 539-44
- Dispatch. Centrosome biology: a SAS-sy centriole in the cell cycle. Curr Biol. 2003; (9): R351-2
- Epsilon-tubulin is required for centriole duplication and microtubule organization. Nat Cell Biol. 2003; (1): 71-6
- Systematic structure-function analysis of the small GTPase Arf1 in yeast. Mol Biol Cell. 2002; (5): 1652-64
- gamma-Tubulin. Curr Biol. 2002; (12): R408-9
- Centrosome duplication. a centriolar pas de deux. Cell. 2001; (4): 417-20
- GCP5 and GCP6: two new members of the human gamma-tubulin complex. Mol Biol Cell. 2001; (11): 3340-52
- Arrest, adaptation, and recovery following a chromosome double-strand break in Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol. 2000: 303-14
- Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function. Nat Cell Biol. 2000; (1): 30-5
- The DNA damage checkpoint signal in budding yeast is nuclear limited. Mol Cell. 2000; (2): 487-92
- Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin. J Cell Biol. 1999; (1): 113-24
- Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle. Genes Dev. 1999; (17): 2242-57
- Cyclin-dependent kinase control of centrosome duplication. Proc Natl Acad Sci U S A. 1999; (6): 2817-22
- Cytoskeletal dynamics in yeast. Methods Cell Biol. 1999: 87-105
- Gamma-tubulin complexes: size does matter. Trends Cell Biol. 1999; (9): 339-42
- The centrosome. Curr Biol. 1999; (9): R315-7
- Centrosome reduction during mouse spermiogenesis. Dev Biol. 1998; (2): 424-34
- Expression of amino- and carboxyl-terminal gamma- and alpha-tubulin mutants in cultured epithelial cells. J Biol Chem. 1998; (5): 2661-8
- Nucleation and capture of large cell surface-associated microtubule arrays that are not located near centrosomes in certain cochlear epithelial cells. J Anat. 1998: 119-30
- Parallel analysis of genetic selections using whole genome oligonucleotide arrays. Proc Natl Acad Sci U S A. 1998; (7): 3752-7
- The mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components spc97p and spc98p. J Cell Biol. 1998; (3): 663-74
- Centrosomal deployment of gamma-tubulin and pericentrin: evidence for a microtubule-nucleating domain and a minus-end docking domain in certain mouse epithelial cells. Cell Motil Cytoskeleton. 1997; (3): 276-90
- Centrosomes isolated from Spisula solidissima oocytes contain rings and an unusual stoichiometric ratio of alpha/beta tubulin. J Cell Biol. 1997; (1): 193-202
- Cytoskeleton: anatomy of an organizing center. Curr Biol. 1997; (12): R754-6
- Microtubules orient the mitotic spindle in yeast through dynein-dependent interactions with the cell cortex. J Cell Biol. 1997; (3): 629-41
- Motoring to the finish: kinesin and dynein work together to orient the yeast mitotic spindle. J Cell Biol. 1997; (5): 957-60
- Synaptically coupled central nervous system neurons lack centrosomal gamma-tubulin. Neurosci Lett. 1997; (1): 17-20
- The cell center at 100. Cell. 1997; (3): 303-9
- Tubulin subunits exist in an activated conformational state generated and maintained by protein cofactors. J Cell Biol. 1997; (4): 821-32
- Analysis of Tub4p, a yeast gamma-tubulin-like protein: implications for microtubule-organizing center function. J Cell Biol. 1996; (2): 443-54
- Cytoskeleton: microtubule nucleation takes shape. Curr Biol. 1996; (6): 642-4
- Green fluorescent protein. The green revolution. Curr Biol. 1995; (3): 262-4
- Mutational analysis of Saccharomyces cerevisiae ARF1. J Biol Chem. 1995; (1): 143-50
- The form and the substance. Nat Med. 1995; (1): 19-20
- In vitro reconstitution of centrosome assembly and function: the central role of gamma-tubulin. Cell. 1994; (4): 623-37
- Specificity domains distinguish the Ras-related GTPases Ypt1 and Sec4. Nature. 1993; (6420): 563-5
- Spindle positioning and cell polarity. Curr Biol. 1992; (9): 469-71
- At the heart of the organizing center. Curr Biol. 1991; (4): 254-6
- Gamma-tubulin is a highly conserved component of the centrosome. Cell. 1991; (5): 825-36
- ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes. Mol Cell Biol. 1990; (12): 6690-9
- ADP-ribosylation factor is functionally and physically associated with the Golgi complex. Proc Natl Acad Sci U S A. 1990; (3): 1238-42
- Chromosome instability mutants of Saccharomyces cerevisiae that are defective in microtubule-mediated processes. Mol Cell Biol. 1990; (1): 223-34
- Manipulating yeast genome using plasmid vectors. Methods Enzymol. 1990: 280-97
- The cytoskeleton of Saccharomyces cerevisiae. Curr Opin Cell Biol. 1990; (1): 109-15
- The yeast microtubule cytoskeleton: genetic approaches to structure and function. Cell Motil Cytoskeleton. 1990; (1): 1-6
- Yeast mutants sensitive to antimicrotubule drugs define three genes that affect microtubule function. Genetics. 1990; (2): 251-62
- DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage. Mol Cell Biol. 1989; (1): 159-68
- Fluorescence microscopy methods for yeast. Methods Cell Biol. 1989: 357-435
- Diverse biological functions of small GTP-binding proteins in yeast. Cold Spring Harb Symp Quant Biol. 1988: 629-36
- Unlinked noncomplementation: isolation of new conditional-lethal mutations in each of the tubulin genes of Saccharomyces cerevisiae. Genetics. 1988; (2): 249-60
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