H Craig Heller
Publications
- Short-term treatment with the GABAA antagonist pentylenetetrazole produces a sustained procognitive benefit in a mouse model of Down's syndrome. Br J Pharmacol. 2013
- The acute effects of light on murine sleep during the dark phase: importance of melanopsin for maintenance of light-induced sleep. Eur J Neurosci. 2013
- Work volume and strength training responses to resistive exercise improve with periodic heat extraction from the palm. J Strength Cond Res. 2012; (9): 2558-69
- Acute light exposure suppresses circadian rhythms in clock gene expression. J Biol Rhythms. 2011; (1): 78-81
- Hibernation in black bears: independence of metabolic suppression from body temperature. Science. 2011; (6019): 906-9
- Optogenetic disruption of sleep continuity impairs memory consolidation. Proc Natl Acad Sci U S A. 2011; (32): 13305-10
- Pumilio-2 function in the mouse nervous system. PLoS One. 2011; (10): e25932
- Repeatability is not the same as accuracy. Sleep. 2011; (7): 839
- Response of the human circadian system to millisecond flashes of light. PLoS One. 2011; (7): e22078
- Circadian locomotor rhythms are normal in Ts65Dn "Down syndrome" mice and unaffected by pentylenetetrazole. J Biol Rhythms. 2010; (1): 63-6
- Separating the contribution of glucocorticoids and wakefulness to the molecular and electrophysiological correlates of sleep homeostasis. Sleep. 2010; (9): 1147-57
- Heat loss through the glabrous skin surfaces of heavily insulated, heat-stressed individuals. J Biomech Eng. 2009; (7): 071005
- Long term repair of learning disability through short-term reduction of CNS inhibition. Augmented Cognition, HCII 2009. D.D. Schmorrow et al. (Eds.). 2009: 818-825
- Melanopsin as a sleep modulator: circadian gating of the direct effects of light on sleep and altered sleep homeostasis in Opn4(-/-) mice. PLoS Biol. 2009; (6): e1000125
- New neurons in the adult brain: the role of sleep and consequences of sleep loss. Sleep Med Rev. 2009; (3): 187-94
- Cooling via one hand improves physical performance in heat-sensitive individuals with multiple sclerosis: a preliminary study. BMC Neurol. 2008: 14
- Hippocampal-dependent learning requires a functional circadian system. Proc Natl Acad Sci U S A. 2008; (40): 15593-8
- A non-circadian role for clock-genes in sleep homeostasis: a strain comparison. BMC Neurosci. 2007: 87
- H. Craig Heller. Interviewed by Laura L. Mays Hoopes. CBE Life Sci Educ. 2007; (4): 275-6
- Pattern recognition of sleep in rodents using piezoelectric signals generated by gross body movements. IEEE Trans Biomed Eng. 2007; (2): 225-33
- Synaptic protein dynamics in hibernation. J Neurosci. 2007; (1): 84-92
- A global rather than local role for adenosine in sleep homeostasis. Sleep. 2006; (11): 1382-3; discussion 1387-9
- Glycogen content in the cerebral cortex increases with sleep loss in C57BL/6J mice. Neurosci Lett. 2006; (1-2): 176-9
- Ubiquitous and temperature-dependent neural plasticity in hibernators. J Neurosci. 2006; (41): 10590-8
- Heat extraction through the palm of one hand improves aerobic exercise endurance in a hot environment. J Appl Physiol. 2005; (3): 972-8
- Lack of the alanine-serine-cysteine transporter 1 causes tremors, seizures, and early postnatal death in mice. Brain Res. 2005; (2): 212-21
- Light induces c-fos and per1 expression in the suprachiasmatic nucleus of arrhythmic hamsters. Am J Physiol Regul Integr Comp Physiol. 2005; (5): R1381-6
- Sleep restriction suppresses neurogenesis induced by hippocampus-dependent learning. J Neurophysiol. 2005; (6): 4224-33
- Unresolved issues in sleep ontogeny: a response to Blumberg et al. J Sleep Res. 2005; (1): 98-101
- Glucocorticoids influence brain glycogen levels during sleep deprivation. Am J Physiol Regul Integr Comp Physiol. 2004; (6): R1057-62
- Homeostatic regulation of sleep in arrhythmic Siberian hamsters. Am J Physiol Regul Integr Comp Physiol. 2004; (1): R104-11
- Light pulses do not induce c-fos or per1 in the SCN of hamsters that fail to reentrain to the photocycle. J Biol Rhythms. 2004; (4): 287-97
- Phenotypic differences in reentrainment behavior and sensitivity to nighttime light pulses in siberian hamsters. J Biol Rhythms. 2004; (6): 530-41
- Sleep and circadian rhythms in mammalian torpor. Annu Rev Physiol. 2004: 275-89
- Sleep deprivation effects on growth factor expression in neonatal rats: a potential role for BDNF in the mediation of delta power. J Neurophysiol. 2004; (4): 1586-95
- Changes in brain glycogen after sleep deprivation vary with genotype. Am J Physiol Regul Integr Comp Physiol. 2003; (2): R413-9
- Differential increase in the expression of heat shock protein family members during sleep deprivation and during sleep. Neuroscience. 2003; (1): 187-200
- Region-specific changes in immediate early gene expression in response to sleep deprivation and recovery sleep in the mouse brain. Neuroscience. 2003; (4): 1115-24
- The ontogeny of mammalian sleep: a reappraisal of alternative hypotheses. J Sleep Res. 2003; (1): 25-34
- Constant darkness restores entrainment to phase-delayed Siberian hamsters. Am J Physiol Regul Integr Comp Physiol. 2002; (6): R1314-20
- Loss of circadian organization of sleep and wakefulness during hibernation. Am J Physiol Regul Integr Comp Physiol. 2002; (4): R1086-95
- Role of melanopsin in circadian responses to light. Science. 2002; (5601): 2211-3
- Sleep deprivation decreases glycogen in the cerebellum but not in the cortex of young rats. Am J Physiol Regul Integr Comp Physiol. 2002; (1): R54-9
- The suprachiasmatic nucleus is essential for circadian body temperature rhythms in hibernating ground squirrels. J Neurosci. 2002; (1): 357-64
- Prenatal nicotine alters vigilance states and AchR gene expression in the neonatal rat: implications for SIDS. Am J Physiol Regul Integr Comp Physiol. 2001; (4): R1134-40
- Sleep deprivation elevates plasma corticosterone levels in neonatal rats. Neurosci Lett. 2001; (1-2): 29-32
- Prepro-hypocretin (prepro-orexin) expression is unaffected by short-term sleep deprivation in rats and mice. Sleep. 2000; (7): 867-74
- Siberian hamsters that fail to reentrain to the photocycle have suppressed melatonin levels. Am J Physiol Regul Integr Comp Physiol. 2000; (3): R757-62
- 8-OH-DPAT-sensitive neurons in the nucleus raphe magnus modulate thermoregulatory output in rats. Brain Res. 1999; (1-2): 155-64
- Circadian rhythms in the suprachiasmatic nucleus are temperature-compensated and phase-shifted by heat pulses in vitro. J Neurosci. 1999; (19): 8630-6
- Developmental changes in nicotinic receptor mRNAs and responses to nicotine in the suprachiasmatic nucleus and other brain regions. Brain Res Mol Brain Res. 1999; (1-2): 71-82
- Gene expression in the brain across the hibernation cycle. J Neurosci. 1999; (10): 3781-90
- HSP70 expression is increased during the day in a diurnal animal, the golden-mantled ground squirrel Spermophilus lateralis. Mol Cell Biochem. 1999; (1-2): 25-34
- Implications of sleep deprivation experiments for our understanding of sleep homeostasis. Sleep. 1999; (8): 1033-43
- Sleep after arousal from hibernation is not homeostatically regulated. Am J Physiol. 1999; (2 Pt 2): R522-9
- The glutamate induced phase shift in the SCN slice: a two pulse study. Brain Res. 1999; (1): 34-40
- Characterization of the circadian system of NGFI-A and NGFI-A/NGFI-B deficient mice. J Biol Rhythms. 1998; (4): 347-57
- Circadian system of mice integrates brief light stimuli. Am J Physiol. 1998; (2 Pt 2): R654-7
- Does the preoptic anterior hypothalamus receive thermoafferent information? Am J Physiol. 1998; (1 Pt 2): R9-18
- Early synaptogenesis in vitro: role of axon target distance. J Comp Neurol. 1998; (4): 541-60
- Effects of sleep deprivation in neonatal rats. Am J Physiol. 1998; (1 Pt 2): R148-57
- Effects of temperature on sleep in the developing rat. Am J Physiol. 1998; (4 Pt 2): R1087-93
- Neurons containing hypocretin (orexin) project to multiple neuronal systems. J Neurosci. 1998; (23): 9996-10015
- Nicotine and nicotinic receptors in the circadian system. Psychoneuroendocrinology. 1998; (2): 161-73
- Phase shift magnitude and direction determine whether Siberian hamsters reentrain to the photocycle. J Biol Rhythms. 1998; (6): 506-17
- Recovery from mild hypothermia can be accelerated by mechanically distending blood vessels in the hand. J Appl Physiol. 1998; (5): 1643-8
- Suprachiasmatic nucleus: role in circannual body mass and hibernation rhythms of ground squirrels. Brain Res. 1998; (1-2): 63-72
- The aged suprachiasmatic nucleus is phase-shifted by cAMP in vitro. Brain Res. 1998; (1-2): 338-41
- Daily variation of CNS gene expression in nocturnal vs. diurnal rodents and in the developing rat brain. Brain Res Mol Brain Res. 1997; (1): 73-86
- Development of REM and slow wave sleep in the rat. Am J Physiol. 1997; (6 Pt 2): R1792-9
- Development of diurnal organization of EEG slow-wave activity and slow-wave sleep in the rat. Am J Physiol. 1997; (2 Pt 2): R472-8
- Melatonin attenuates photic disruption of circadian rhythms in Siberian hamsters. Am J Physiol. 1997; (4 Pt 2): R1540-9
- Metabotropic glutamate receptor activation modulates kainate and serotonin calcium response in astrocytes. J Neurosci. 1997; (5): 1825-37
- Neonatal treatments with the serotonin uptake inhibitors clomipramine and zimelidine, but not the noradrenaline uptake inhibitor desipramine, disrupt sleep patterns in adult rats. Brain Res. 1997; (1-2): 287-93
- The effects of REM sleep-inhibiting drugs in neonatal rats: evidence for a distinction between neonatal active sleep and REM sleep. Brain Res. 1997; (1): 64-72
- Ablation of suprachiasmatic nucleus alters timing of hibernation in ground squirrels. Proc Natl Acad Sci U S A. 1996; (18): 9864-8
- Appropriate thermal manipulations eliminate tremors in rats recovering from halothane anesthesia. J Appl Physiol. 1996; (6): 2547-54
- Siberian hamsters free run or become arrhythmic after a phase delay of the photocycle. Am J Physiol. 1996; (4 Pt 2): R881-90
- Temperature sensitivity of sleep homeostasis during hibernation in the golden-mantled ground squirrel. Am J Physiol. 1996; (4 Pt 2): R777-84
- Temperature sensitivity of the suprachiasmatic nucleus of ground squirrels and rats in vitro. J Biol Rhythms. 1996; (2): 126-36
- Adenosine pre- and postsynaptic modulation of glutamate-dependent calcium activity in hypothalamic neurons. J Neurophysiol. 1995; (5): 2150-62
- Apamin, a selective SK potassium channel blocker, suppresses REM sleep without a compensatory rebound. Brain Res. 1995; (1-2): 86-92
- GABAA, GABAC, and NMDA receptor subunit expression in the suprachiasmatic nucleus and other brain regions. Brain Res Mol Brain Res. 1995; (2): 239-50
- Monoaminergic and cholinergic modulation of REM-sleep timing in rats. Brain Res. 1995; (1-2): 141-6
- Nicotine administration differentially affects gene expression in the maternal and fetal circadian clock. Brain Res Dev Brain Res. 1995; (1): 46-54
- Nicotine phase-advances the circadian neuronal activity rhythm in rat suprachiasmatic nuclei explants. Neuroscience. 1995; (3): 797-803
- Restoration of brain energy metabolism as the function of sleep. Prog Neurobiol. 1995; (4): 347-60
- Sequence and tissue distribution of a candidate G-coupled receptor cloned from rat hypothalamus. Biochem Biophys Res Commun. 1995; (2): 606-13
- Stimulation of A1 adenosine receptors mimics the electroencephalographic effects of sleep deprivation. Brain Res. 1995; (1-2): 79-85
- A possible glial role in the mammalian circadian clock. Brain Res. 1994; (1-2): 296-301
- C-fos mRNA increases in the ground squirrel suprachiasmatic nucleus during arousal from hibernation. Neurosci Lett. 1994; (1-2): 117-21
- Chloride channel block phase advances the single-unit activity rhythm in the SCN. Brain Res Bull. 1994; (1): 69-72
- Does the function of REM sleep concern non-REM sleep or waking? Prog Neurobiol. 1994; (5): 433-49
- Ontogeny of photic-induced c-fos mRNA expression in rat suprachiasmatic nuclei. Neuroreport. 1994; (18): 2683-7
- Persistence of circadian rhythmicity in hibernating ground squirrels. Am J Physiol. 1994; (4 Pt 2): R1251-8
- REM-sleep propensity accumulates during 2-h REM-sleep deprivation in the rest period in rats. Neurosci Lett. 1994; (1): 76-80
- REM-sleep timing is controlled homeostatically by accumulation of REM-sleep propensity in non-REM sleep. Am J Physiol. 1994; (6 Pt 2): R1992-2000
- Scoring transitions to REM sleep in rats based on the EEG phenomena of pre-REM sleep: an improved analysis of sleep structure. Sleep. 1994; (1): 28-36
- Serotonergic phase advances of the mammalian circadian clock involve protein kinase A and K+ channel opening. Brain Res. 1994; (1): 67-73
- Thermal effects on neuronal activity in suprachiasmatic nuclei of hibernators and nonhibernators. Am J Physiol. 1994; (4 Pt 2): R1259-66
- c-fos mRNA in the suprachiasmatic nuclei in vitro shows a circadian rhythm and responds to a serotonergic agonist. Brain Res Mol Brain Res. 1994; (1-2): 151-6
- Light-induced gene expression in the suprachiasmatic nucleus of young and aging rats. Neurobiol Aging. 1993 Sep-Oct; (5): 441-6
- Immediate early gene expression in brain during sleep deprivation: preliminary observations. Sleep. 1993; (1): 1-7
- Serotonin and the mammalian circadian system: I. In vitro phase shifts by serotonergic agonists and antagonists. J Biol Rhythms. 1993; (1): 1-16
- Melatonin influences Fos expression in the rat suprachiasmatic. Brain Res Mol Brain Res. 1992; (1-2): 47-56
- Monoaminc and metabolite levels in the cerebrospinal fluid of hibernating and euthermic marmots. J Sleep Res. 1992; (1): 45-50
- Serotonergic phase shifts of the mammalian circadian clock: effects of tetrodotoxin and high Mg2+. Brain Res. 1992; (2): 336-40
- Sleep homeostasis in suprachiasmatic nuclei-lesioned rats: effects of sleep deprivation and triazolam administration. Brain Res. 1992; (2): 253-61
- Are ground squirrels sleep deprived during hibernation? Am J Physiol. 1991; (6 Pt 2): R1123-9
- Regional changes in central monoamine and metabolite levels during the hibernation cycle in the golden-mantled ground squirrel. Brain Res. 1991; (1-2): 215-20
- Reticular formation activity during wakefulness and sleep in a hibernator (Spermophilus lateralis). Brain Res. 1991; (1-2): 266-72
- 14C-2-deoxyglucose uptake in the ground squirrel brain during entrance to and arousal from hibernation. J Neurosci. 1990; (7): 2463-75
- A serotonin agonist phase-shifts the circadian clock in the suprachiasmatic nuclei in vitro. Brain Res. 1990; (1-2): 336-9
- Suprachiasmatic nuclei influence hibernation rhythms of golden-mantled ground squirrels. Brain Res. 1990; (1): 111-8
- Action potential duration increases as body temperature decreases during hibernation. Brain Res. 1989; (1): 73-80
- Activity of most rostral ventromedial medulla neurons reflect EEG/EMG pattern changes. Am J Physiol. 1989; (6 Pt 2): R1496-505
- Arousal state vs. temperature effects on neuronal activity in subcoeruleus area. Am J Physiol. 1989; (4 Pt 2): R840-9
- Regulated nocturnal hypothermia induced in pigeons by food deprivation. Am J Physiol. 1989; (3 Pt 2): R733-8
- Suprachiasmatic nucleus: phase-dependent activation during the hibernation cycle. Am J Physiol. 1989; (3 Pt 2): R605-12
- Neuronal activity during sleep and complete bouts of hibernation. Am J Physiol. 1988; (6 Pt 2): R1008-19
- Progressive activation of paratrigeminal nucleus during entrance to hibernation. Am J Physiol. 1988; (1 Pt 2): R178-81
- Absence of a circadian rhythm of protein synthesis in the rat suprachiasmatic nucleus. Neurosci Lett. 1987; (1): 113-8
- Activity of suprachiasmatic and hypothalamic neurons during sleep and wakefulness in the rat. Brain Res. 1987; (1-2): 279-86
- Influence of spinal and hypothalamic warming on metabolism and sleep in pigeons. Am J Physiol. 1987; (4 Pt 2): R661-7
- Modulation of activity of the striatal dopaminergic system during the hibernation cycle. J Neurosci. 1987; (9): 2732-6
- Changes in the thermal characteristics of hypothalamic neurons during sleep and wakefulness. Brain Res. 1984; (1): 17-26
- Circadian and arousal state influences on thermoregulation in the pigeon. Am J Physiol. 1983; (3): R321-8
- Metabolic activation of the brachium conjunctivum during induced hypothermia. Brain Res. 1983; (1): 168-71
- Relative 2-deoxyglucose uptake of the paratrigeminal nucleus increases during hibernation. Brain Res. 1983; (1): 117-23
- The physiology of hibernation. Science. 1983; (4597): 599-600
- The relationship of local cerebral glucose utilization to optical density ratios. Brain Res. 1983; (1): 97-103
- Autoradiographic patterns of hippocampal metabolism during induced hypothermia. Neurosci Lett. 1982; (3): 233-9
- [14C]2-deoxyglucose uptake in ground squirrel brain during hibernation. J Neurosci. 1982; (2): 143-57
- Hibernation at moderate temperatures: a continuation of slow wave sleep. Experientia. 1981; (7): 726-8
- Metabolism and thermoregulation during stages of sleep in humans exposed to heat and cold. J Appl Physiol. 1981; (4): 948-54
- The effects of high and low ambient temperatures on human sleep stages. Electroencephalogr Clin Neurophysiol. 1981; (5): 494-501
- Hibernation: neural aspects. Annu Rev Physiol. 1979: 305-21
- Influence of hypothalamic and ambient temperatures on sleep in kangaroo rats. Am J Physiol. 1979; (1): R80-8
- Sleep and estivation (shallow torpor): continuous processes of energy conservation. Science. 1979; (4397): 1098-100
- Hypothalamic thermosensitivity in mammals. Experientia Suppl. 1978: 267-76
- Temperature regulation during wakefulness, sleep, and hibernation in marmots. Am J Physiol. 1978; (1): R82-8
- The thermostat of vertebrate animals. Sci Am. 1978; (2): 102-10, 112-3
- CNS regulation of body temperature in euthermic and hibernating marmots (Marmota flaviventris). Am J Physiol. 1977; (5): R203-8
- Sleep and hibernation in ground squirrels (Citellus spp): electrophysiological observations. Am J Physiol. 1977; (5): R213-21
- Thermoregulation during entrance into hibernation. Pflugers Arch. 1977; (1): 55-9
- Thermoregulation during sleep and hibernation. Int Rev Physiol. 1977: 147-88
- Thermoregulatory responses to altering hypothalamic temperature in the harbor seal. Am J Physiol. 1977; (1): R18-26
- Central nervous regulation of body temperature during sleep. Science. 1976; (4264): 537-9
- Hypothalamic thermosensitivity and regulation of heat storage behavior in a diurnal desert ground squirrel (Ammospermophilus nelsoni). Isr J Med Sci. 1976; (9): 1029-32
- CNS regulation of metabolic rate in the kangaroo rat Dipodomys ingens. Am J Physiol. 1975; (6): 1880-6
- Elevated blood glucose levels and satiety in the rat. Physiol Behav. 1975; (2): 137-43
- CNS regulation of body temperature during hibernation. Am J Physiol. 1974; (3): 583-9
- CNS regulation of body temperature in euthermic hibernators. Am J Physiol. 1974; (3): 576-82
- Probing the rostral brainstem of anesthetized, unanesthetized, and exercising dogs and of hibernating and euthermic ground squirrels. Fed Proc. 1973; (5): 1588-97
- CNS control of body temperature during hibernation. Comp Biochem Physiol A Comp Physiol. 1972; (2): 349-59
- CNS regulation of body temperature in the hibernator Citellus lateralis. Int J Biometeorol. 1971; (2): 231-5
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