Sylvia K. Plevritis, PhD
Publications
- A simulation model to predict the impact of prophylactic surgery and screening on the life expectancy of BRCA1 and BRCA2 mutation carriers. Cancer Epidemiol Biomarkers Prev. 2012; (7): 1066-77
- Comparing the benefits of screening for breast cancer and lung cancer using a novel natural history model. Cancer Causes Control. 2012; (1): 175-85
- CytoSPADE: high-performance analysis and visualization of high-dimensional cytometry data. Bioinformatics. 2012; (18): 2400-1
- Non-small cell lung cancer: identifying prognostic imaging biomarkers by leveraging public gene expression microarray data--methods and preliminary results. Radiology. 2012; (2): 387-96
- Online tool to guide decisions for BRCA1/2 mutation carriers. J Clin Oncol. 2012; (5): 497-506
- Prognostic PET 18F-FDG uptake imaging features are associated with major oncogenomic alterations in patients with resected non-small cell lung cancer. Cancer Res. 2012; (15): 3725-34
- Discovering biological progression underlying microarray samples. PLoS Comput Biol. 2011; (4): e1001123
- Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. Nat Biotechnol. 2011; (10): 886-91
- Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction. Proc Natl Acad Sci U S A. 2011; (42): 17432-7
- Prediction of survival in diffuse large B-cell lymphoma based on the expression of 2 genes reflecting tumor and microenvironment. Blood. 2011; (5): 1350-8
- Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011; (6030): 687-96
- A simulation model investigating the impact of tumor volume doubling time and mammographic tumor detectability on screening outcomes in women aged 40-49 years. J Natl Cancer Inst. 2010; (16): 1263-71
- Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia. JAMA. 2010; (24): 2706-15
- Incidental extracardiac findings at coronary CT: clinical and economic impact. AJR Am J Roentgenol. 2010; (6): 1531-8
- MiDReG: a method of mining developmentally regulated genes using Boolean implications. Proc Natl Acad Sci U S A. 2010; (13): 5732-7
- Reducing the computational complexity of information theoretic approaches for reconstructing gene regulatory networks. J Comput Biol. 2010; (2): 169-76
- Survival analysis of cancer risk reduction strategies for BRCA1/2 mutation carriers. J Clin Oncol. 2010; (2): 222-31
- Characterization of patient specific signaling via augmentation of Bayesian networks with disease and patient state nodes. Conf Proc IEEE Eng Med Biol Soc. 2009: 6624-7
- Effects of mammography screening under different screening schedules: model estimates of potential benefits and harms. Ann Intern Med. 2009; (10): 738-47
- Fast calculation of pairwise mutual information for gene regulatory network reconstruction. Comput Methods Programs Biomed. 2009; (2): 177-80
- Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev. 2009; (20): 2376-81
- Modeling the transition of lung cancer from early to advanced stage. Cancer Causes Control. 2009; (9): 1559-69
- Simultaneous class discovery and classification of microarray data using spectral analysis. J Comput Biol. 2009; (7): 935-44
- Boolean implication networks derived from large scale, whole genome microarray datasets. Genome Biol. 2008; (10): R157
- Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance. Cancer Res. 2008; (13): 5132-42
- Ductal pattern enhancement on magnetic resonance imaging of the breast due to ductal lavage. Breast J. 2007 May-Jun; (3): 281-6
- A natural history model of stage progression applied to breast cancer. Stat Med. 2007; (3): 581-95
- Extracting binary signals from microarray time-course data. Nucleic Acids Res. 2007; (11): 3705-12
- A stochastic simulation model of U.S. breast cancer mortality trends from 1975 to 2000. J Natl Cancer Inst Monogr. 2006; (36): 86-95
- Cost-effectiveness of screening BRCA1/2 mutation carriers with breast magnetic resonance imaging. JAMA. 2006; (20): 2374-84
- Decision analysis and simulation modeling for evaluating diagnostic tests on the basis of patient outcomes. AJR Am J Roentgenol. 2005; (3): 581-90
- Effect of screening and adjuvant therapy on mortality from breast cancer. N Engl J Med. 2005; (17): 1784-92
- The effect of age, race, tumor size, tumor grade, and disease stage on invasive ductal breast cancer survival in the U.S. SEER database. Breast Cancer Res Treat. 2005; (1): 47-54
- Breast magnetic resonance image screening and ductal lavage in women at high genetic risk for breast carcinoma. Cancer. 2004; (3): 479-89
- Simulation-based parameter estimation for complex models: a breast cancer natural history modelling illustration. Stat Methods Med Res. 2004; (6): 507-24
- Spectral extrapolation of spatially bounded images [MRI application]. IEEE Trans Med Imaging. 1995; (3): 487-97
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