Karla Kirkegaard
Publications
- Potential subversion of autophagosomal pathway by picornaviruses. Autophagy. 2008; (3): 286-9
- Modification of cellular autophagy protein LC3 by poliovirus. J Virol. 2007; (22): 12543-53
- Bottleneck-mediated quasispecies restriction during spread of an RNA virus from inoculation site to brain. Proc Natl Acad Sci U S A. 2006; (14): 5520-5
- Intramolecular and intermolecular uridylylation by poliovirus RNA-dependent RNA polymerase. J Virol. 2006; (15): 7405-15
- Nucleotide channel of RNA-dependent RNA polymerase used for intermolecular uridylylation of protein primer. J Mol Biol. 2006; (2): 665-75
- Topology of double-membraned vesicles and the opportunity for non-lytic release of cytoplasm. Autophagy. 2005 Oct-Dec; (3): 182-4
- Allosteric effects of ligands and mutations on poliovirus RNA-dependent RNA polymerase. J Virol. 2005; (12): 7803-11
- Increased fidelity reduces poliovirus fitness and virulence under selective pressure in mice. PLoS Pathog. 2005; (2): e11
- Inhibition of cellular protein secretion by picornaviral 3A proteins. Virology. 2005; (1): 18-29
- Ribavirin resistance in hepatitis C virus replicon-containing cell lines conferred by changes in the cell line or mutations in the replicon RNA. J Virol. 2005; (4): 2346-55
- Subversion of cellular autophagosomal machinery by RNA viruses. PLoS Biol. 2005; (5): e156
- Trans-dominant inhibition of RNA viral replication can slow growth of drug-resistant viruses. Nat Genet. 2005; (7): 701-9
- Cellular autophagy: surrender, avoidance and subversion by microorganisms. Nat Rev Microbiol. 2004; (4): 301-14
- Intracellular topology and epitope shielding of poliovirus 3A protein. J Virol. 2004; (11): 5973-82
- A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity. Proc Natl Acad Sci U S A. 2003; (12): 7289-94
- Nonstructural protein precursor NS4A/B from hepatitis C virus alters function and ultrastructure of host secretory apparatus. J Virol. 2003; (14): 7843-55
- Oligomerization and cooperative RNA synthesis activity of hepatitis C virus RNA-dependent RNA polymerase. J Virol. 2002; (8): 3865-72
- Similar structural basis for membrane localization and protein priming by an RNA-dependent RNA polymerase. J Biol Chem. 2002; (18): 16324-31
- Visualization and functional analysis of RNA-dependent RNA polymerase lattices. Science. 2002; (5576): 2218-22
- Poliovirus 3A protein limits interleukin-6 (IL-6), IL-8, and beta interferon secretion during viral infection. J Virol. 2001; (17): 8158-65
- MHC I-dependent antigen presentation is inhibited by poliovirus protein 3A. Proc Natl Acad Sci U S A. 2000; (25): 13790-5
- Remodeling the endoplasmic reticulum by poliovirus infection and by individual viral proteins: an autophagy-like origin for virus-induced vesicles. J Virol. 2000; (19): 8953-65
- Functional coupling between replication and packaging of poliovirus replicon RNA. J Virol. 1999; (1): 427-35
- KH domain integrity is required for wild-type localization of Sam68. Exp Cell Res. 1998; (1): 84-95
- Site size of cooperative single-stranded RNA binding by poliovirus RNA-dependent RNA polymerase. J Biol Chem. 1998; (12): 6724-30
- Inhibition of endoplasmic reticulum-to-Golgi traffic by poliovirus protein 3A: genetic and ultrastructural analysis. J Virol. 1997; (12): 9054-64
- Poliovirus RNA recombination in cell-free extracts. RNA. 1997; (6): 624-33
- Cellular origin and ultrastructure of membranes induced during poliovirus infection. J Virol. 1996; (10): 6576-88
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