Matt van de Rijn
Publications
- Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth. Proc Natl Acad Sci U S A. 2013; (9): 3501-6
- Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types. PLoS Genet. 2013; (4): e1003464
- Desktop transcriptome sequencing from archival tissue to identify clinically relevant translocations. Am J Surg Pathol. 2013; (6): 796-803
- Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma. Proc Natl Acad Sci U S A. 2012; (17): 6656-61
- CDX2 is an amplified lineage-survival oncogene in colorectal cancer. Proc Natl Acad Sci U S A. 2012; (46): E3196-205
- Comparative gene expression profiling of benign and malignant lesions reveals candidate therapeutic compounds for leiomyosarcoma. Sarcoma. 2012: 805614
- Cyclin D1 as a diagnostic immunomarker for endometrial stromal sarcoma with YWHAE-FAM22 rearrangement. Am J Surg Pathol. 2012; (10): 1562-70
- Flipping the script on macrophages in leiomyosarcoma. Oncoimmunology. 2012; (7): 1202-1204
- ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour. J Pathol. 2012; (2): 223-33
- Sox10 and S100 in the diagnosis of soft-tissue neoplasms. Appl Immunohistochem Mol Morphol. 2012; (5): 445-50
- The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. Proc Natl Acad Sci U S A. 2012; (17): 6662-7
- The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor. Am J Surg Pathol. 2012; (5): 641-53
- Three differentiation states risk-stratify bladder cancer into distinct subtypes. Proc Natl Acad Sci U S A. 2012; (6): 2078-83
- A tri-marker proliferation index predicts biochemical recurrence after surgery for prostate cancer. PLoS One. 2011; (5): e20293
- CSF1 expression in nongynecological leiomyosarcoma is associated with increased tumor angiogenesis. Am J Pathol. 2011; (4): 2100-7
- Endogenous versus tumor-specific host response to breast carcinoma: a study of stromal response in synchronous breast primaries and biopsy site changes. Clin Cancer Res. 2011; (3): 437-46
- Expression of subtype-specific group 1 leiomyosarcoma markers in a wide variety of sarcomas by gene expression analysis and immunohistochemistry. Am J Surg Pathol. 2011; (4): 583-9
- SMURF1 amplification promotes invasiveness in pancreatic cancer. PLoS One. 2011; (8): e23924
- Systematic analysis of breast cancer morphology uncovers stromal features associated with survival. Sci Transl Med. 2011; (108): 108ra113
- 3'-end sequencing for expression quantification (3SEQ) from archival tumor samples. PLoS One. 2010; (1): e8768
- Analysis of stromal signatures in the tumor microenvironment of ductal carcinoma in situ. Breast Cancer Res Treat. 2010; (2): 397-404
- DOG1 for the diagnosis of gastrointestinal stromal tumor (GIST): Comparison between 2 different antibodies. Appl Immunohistochem Mol Morphol. 2010; (4): 333-7
- Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling. Oncogene. 2010; (6): 845-54
- Gene expression profiling for the investigation of soft tissue sarcoma pathogenesis and the identification of diagnostic, prognostic, and predictive biomarkers. Virchows Arch. 2010; (2): 141-51
- Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature. 2010; (7302): 133-7
- Variations in stromal signatures in breast and colorectal cancer metastases. J Pathol. 2010; (2): 158-65
- Coordinate expression of colony-stimulating factor-1 and colony-stimulating factor-1-related proteins is associated with poor prognosis in gynecological and nongynecological leiomyosarcoma. Am J Pathol. 2009; (6): 2347-56
- Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc Natl Acad Sci U S A. 2009; (33): 14016-21
- LC3-mediated fibronectin mRNA translation induces fibrosarcoma growth by increasing connective tissue growth factor. J Cell Sci. 2009; (Pt 9): 1441-51
- The macrophage colony-stimulating factor 1 response signature in breast carcinoma. Clin Cancer Res. 2009; (3): 778-87
- A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors. Am J Surg Pathol. 2008; (2): 210-8
- A systems biology approach to anatomic diversity of skin. J Invest Dermatol. 2008; (4): 776-82
- Characterization of a novel anti-fatty acid synthase (FASN) antiserum in breast tissue. Mod Pathol. 2008; (12): 1413-20
- Diffuse myogenin expression by immunohistochemistry is an independent marker of poor survival in pediatric rhabdomyosarcoma: a tissue microarray study of 71 primary tumors including correlation with molecular phenotype. Am J Surg Pathol. 2008; (10): 1513-22
- Gene expression profiling identifies p63 as a diagnostic marker for giant cell tumor of the bone. Mod Pathol. 2008; (5): 531-9
- Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancer. PLoS Genet. 2008; (5): e1000081
- Immunohistochemical and biogenetic features of diffuse-type tenosynovial giant cell tumors: the potential roles of cyclin A, P53, and deletion of 15q in sarcomatous transformation. Clin Cancer Res. 2008; (19): 6023-32
- MicroRNA expression signature of human sarcomas. Oncogene. 2008; (14): 2015-26
- Prognostic significance of macrophage infiltration in leiomyosarcomas. Clin Cancer Res. 2008; (5): 1423-30
- The Stanford Tissue Microarray Database. Nucleic Acids Res. 2008; (Database issue): D871-7
- The fibromatosis signature defines a robust stromal response in breast carcinoma. Lab Invest. 2008; (6): 591-601
- hCAP-D3 expression marks a prostate cancer subtype with favorable clinical behavior and androgen signaling signature. Am J Surg Pathol. 2008; (2): 205-9
- A variant TMPRSS2 isoform and ERG fusion product in prostate cancer with implications for molecular diagnosis. Mod Pathol. 2007; (4): 467-73
- Experimental approaches to the study of cancer-stroma interactions: recent findings suggest a pivotal role for stroma in carcinogenesis. Lab Invest. 2007; (10): 967-70
- Gene expression patterns in pancreatic tumors, cells and tissues. PLoS One. 2007; (3): e323
- Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors. Am J Pathol. 2007; (5): 1793-805
- Placental S100 (S100P) and GATA3: markers for transitional epithelium and urothelial carcinoma discovered by complementary DNA microarray. Am J Surg Pathol. 2007; (5): 673-80
- TLE1 as a diagnostic immunohistochemical marker for synovial sarcoma emerging from gene expression profiling studies. Am J Surg Pathol. 2007; (2): 240-6
- The utility of PAX5 immunohistochemistry in the diagnosis of undifferentiated malignant neoplasms. Mod Pathol. 2007; (8): 871-7
- Translocation and expression of CSF1 in pigmented villonodular synovitis, tenosynovial giant cell tumor, rheumatoid arthritis and other reactive synovitides. Am J Surg Pathol. 2007; (6): 970-6
- A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells. Proc Natl Acad Sci U S A. 2006; (3): 690-5
- Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation. Proc Natl Acad Sci U S A. 2006; (40): 14842-7
- Genetics of soft tissue tumors. Annu Rev Pathol. 2006: 435-66
- Ossifying fibromyxoid tumor of soft parts presenting as a scalp cyst. J Cutan Pathol. 2006; (8): 569-72
- The role of microarray technologies in the study of soft tissue tumours. Histopathology. 2006; (1): 22-31
- Upregulation of histidine decarboxylase expression in superficial cortical nephrons during pregnancy in mice and women. Kidney Int. 2006; (2): 306-14
- A DNA microarray survey of gene expression in normal human tissues. Genome Biol. 2005; (3): R22
- A novel method for making "tissue" microarrays from small numbers of suspension cells. Appl Immunohistochem Mol Morphol. 2005; (1): 80-4
- Determination of stromal signatures in breast carcinoma. PLoS Biol. 2005; (6): e187
- Distinction between serous tumors of low malignant potential and serous carcinomas based on global mRNA expression profiling. Gynecol Oncol. 2005; (3): 684-94
- Familial gastrointestinal stromal tumor syndrome: phenotypic and molecular features in a kindred. J Clin Oncol. 2005; (12): 2735-43
- Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc Natl Acad Sci U S A. 2005; (10): 3738-43
- Screening of tissue microarrays for ubiquitin proteasome system components in tumors. Methods Enzymol. 2005: 334-55
- TMA-Combiner, a simple software tool to permit analysis of replicate cores on tissue microarrays. Mod Pathol. 2005; (12): 1641-8
- The gene expression profile of extraskeletal myxoid chondrosarcoma. J Pathol. 2005; (4): 433-44
- The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer. Cancer Res. 2005; (18): 8118-24
- Apo D in soft tissue tumors: a novel marker for dermatofibrosarcoma protuberans. Am J Surg Pathol. 2004; (8): 1063-9
- Applications of microarrays to histopathology. Histopathology. 2004; (2): 97-108
- Gastrointestinal stromal tumors (GISTs) with KIT and PDGFRA mutations have distinct gene expression profiles. Oncogene. 2004; (47): 7780-90
- Gene expression in the normal adult human kidney assessed by complementary DNA microarray. Mol Biol Cell. 2004; (2): 649-56
- Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proc Natl Acad Sci U S A. 2004; (3): 811-6
- Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS Biol. 2004; (2): E7
- Hierarchical clustering analysis of tissue microarray immunostaining data identifies prognostically significant groups of breast carcinoma. Clin Cancer Res. 2004; (18 Pt 1): 6143-51
- High-resolution array-based comparative genomic hybridization for distinguishing paraffin-embedded Spitz nevi and melanomas. Diagn Mol Pathol. 2004; (1): 22-5
- Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res. 2004; (16): 5367-74
- Novel endothelial cell markers in hepatocellular carcinoma. Mod Pathol. 2004; (10): 1198-210
- The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status. Am J Pathol. 2004; (1): 107-13
- Endothelial cell diversity revealed by global expression profiling. Proc Natl Acad Sci U S A. 2003; (19): 10623-8
- Expression of FKBP12 in benign and malignant vascular endothelium: an immunohistochemical study on conventional sections and tissue microarrays. Am J Surg Pathol. 2003; (1): 58-64
- Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans. Am J Pathol. 2003; (6): 2383-95
- Gene expression patterns in ovarian carcinomas. Mol Biol Cell. 2003; (11): 4376-86
- Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarray. Am J Pathol. 2003; (3): 925-32
- Hep par 1 antibody stain for the differential diagnosis of hepatocellular carcinoma: 676 tumors tested using tissue microarrays and conventional tissue sections. Mod Pathol. 2003; (2): 137-44
- Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology. Am J Pathol. 2003; (4): 1449-56
- Challenges in developing a molecular characterization of cancer. Semin Oncol. 2002; (3): 280-5
- Diversity, topographic differentiation, and positional memory in human fibroblasts. Proc Natl Acad Sci U S A. 2002; (20): 12877-82
- Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome. Am J Pathol. 2002; (6): 1991-6
- Gene expression patterns in human liver cancers. Mol Biol Cell. 2002; (6): 1929-39
- Gene expression studies on soft tissue tumors. Am J Pathol. 2002; (5): 1531-4
- Molecular characterisation of soft tissue tumours: a gene expression study. Lancet. 2002; (9314): 1301-7
- Software tools for high-throughput analysis and archiving of immunohistochemistry staining data obtained with tissue microarrays. Am J Pathol. 2002; (5): 1557-65
- Tissue microarrays are an effective quality assurance tool for diagnostic immunohistochemistry. Mod Pathol. 2002; (12): 1374-80
- Analysis of MUM1/IRF4 protein expression using tissue microarrays and immunohistochemistry. Mod Pathol. 2001; (7): 686-94
- Diversity of gene expression in adenocarcinoma of the lung. Proc Natl Acad Sci U S A. 2001; (24): 13784-9
- Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A. 2001; (19): 10869-74
- Orbital hemangiopericytoma and solitary fibrous tumor: a morphologic continuum. Int J Surg Pathol. 2001; (4): 295-302
- Towards a novel classification of human malignancies based on gene expression patterns. J Pathol. 2001; (1): 41-52
- CD40L, but not CD40, is required for allergen-induced bronchial hyperresponsiveness in mice. Am J Respir Cell Mol Biol. 2000; (5): 646-51
- Immunoblot analysis of CD34 expression in histologically diverse neoplasms. Am J Pathol. 2000; (1): 21-7
- Molecular portraits of human breast tumours. Nature. 2000; (6797): 747-52
- Peripheral T-cell lymphoma complicated by a proliferation of large B cells. Am J Clin Pathol. 2000; (2): 236-47
- Systematic variation in gene expression patterns in human cancer cell lines. Nat Genet. 2000; (3): 227-35
- A population based, case control study of non-Hodgkin's lymphoma in patients with rheumatoid arthritis. J Rheumatol. 1999; (8): 1676-80
- Absence of SYT-SSX fusion products in soft tissue tumors other than synovial sarcoma. Am J Clin Pathol. 1999; (1): 43-9
- Colonic adenocarcinoma presenting as supraclavicular lymphadenopathy in a 26-yr-old man: a case report. Am J Gastroenterol. 1999; (1): 282-3
- Detection of a variant SYT-SSX1 fusion in a case of predominantly epithelioid synovial sarcoma. Mol Diagn. 1999; (1): 65-70
- Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc Natl Acad Sci U S A. 1999; (16): 9212-7
- Poorly differentiated synovial sarcoma: an analysis of clinical, pathologic, and molecular genetic features. Am J Surg Pathol. 1999; (1): 106-12
- A murine model of allergic rhinitis: studies on the role of IgE in pathogenesis and analysis of the eosinophil influx elicited by allergen and eotaxin. J Allergy Clin Immunol. 1998; (1): 65-74
- Immunohistochemical analysis of gel-transferred cells in cytologic preparations following smear division. Diagn Cytopathol. 1998; (5): 377-80
- Interleukin-9 promotes allergen-induced eosinophilic inflammation and airway hyperresponsiveness in transgenic mice. Am J Respir Cell Mol Biol. 1998; (5): 713-20
- Sensitivity and specificity of antibodies on necrotic tumor tissue. Am J Clin Pathol. 1998; (5): 641-6
- Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma. Proc Natl Acad Sci U S A. 1997; (4): 1344-9
- CD5 immunostaining of lymphoid neoplasms in paraffin sections. Am J Clin Pathol. 1997; (4): 496; author reply 497
- Extranodal head and neck lymphomas in Guatemala: high frequency of Epstein-Barr virus-associated sinonasal lymphomas. Hum Pathol. 1997; (7): 834-9
- Primary low-grade endometrial B-cell lymphoma. Am J Surg Pathol. 1997; (2): 187-94
- Radiation-associated synovial sarcoma. Hum Pathol. 1997; (11): 1325-8
- Clonality of Epstein-Barr virus in lymphoproliferative disorders in patients treated with immunosuppressive therapy for rheumatoid arthritis. J Clin Oncol. 1996; (11): 3050-1
- Eotaxin triggers eosinophil-selective chemotaxis and calcium flux via a distinct receptor and induces pulmonary eosinophilia in the presence of interleukin 5 in mice. Mol Med. 1996; (3): 334-48
- Epstein-Barr virus clonality in lymphomas occurring in patients with rheumatoid arthritis. Arthritis Rheum. 1996; (4): 638-42
- Hodgkin's disease and lymphoproliferations resembling Hodgkin's disease in patients receiving long-term low-dose methotrexate therapy. Am J Surg Pathol. 1996; (10): 1279-87
- Pregnancy-associated lymphomas. A clinicopathologic study. Cancer. 1996; (2): 304-10
- RANTES chemokine expression in diseased and normal human tissues. Cytokine. 1996; (1): 89-98
- Clonal VDJ recombination of the immunoglobulin heavy chain gene by PCR in classical Hodgkin's disease. Am J Clin Pathol. 1995; (4): 419-23
- Cyclosporine and methotrexate for severe rheumatoid arthritis. N Engl J Med. 1995; (23): 1568; author reply 1568-9
- Detection of Epstein-Barr virus in cardiac biopsies of heart transplant patients with lymphoproliferative disorders. Transplantation. 1995; (5): 471-3
- Frequent presence of the Epstein-Barr virus in inflammatory pseudotumor. Hum Pathol. 1995; (10): 1093-8
- Immunosuppression-associated lymphoproliferative disorders in rheumatic patients. Leuk Lymphoma. 1995; (5-6): 363-8
- Virus-associated hemophagocytic syndrome characterized by clonal Epstein-Barr virus genome. Am J Clin Pathol. 1995; (2): 189-94
- bcl-2 expression in melanocytic nevi. Insights into the biology of dermal maturation. Arch Dermatol. 1995; (8): 915-8
- bcl-2 expression in primary malignancies of the skin. Arch Dermatol. 1995; (8): 909-12
- A comparative immunohistochemical study of uterine smooth muscle neoplasms with emphasis on the epithelioid variant. Hum Pathol. 1994; (7): 671-7
- Bcl-2 immunoreactivity in breast carcinoma correlates with hormone receptor positivity. Am J Pathol. 1994; (3): 535-40
- CD34 expression by gastrointestinal tract stromal tumors. Hum Pathol. 1994; (8): 766-71
- Epstein-Barr virus-associated natural killer-large granular lymphocyte leukemia. Hum Pathol. 1994; (9): 953-60
- Expression of CD34 by solitary fibrous tumors of the pleura, mediastinum, and lung. Am J Surg Pathol. 1994; (8): 814-20
- Lymphoid neoplasms in patients with rheumatoid arthritis and dermatomyositis: frequency of Epstein-Barr virus and other features associated with immunosuppression. Hum Pathol. 1994; (7): 638-43
- bcl-2 expression reliably distinguishes trichoepitheliomas from basal cell carcinomas. Br J Dermatol. 1994; (1): 28-31
- Brief report: reversible lymphomas associated with Epstein-Barr virus occurring during methotrexate therapy for rheumatoid arthritis and dermatomyositis. N Engl J Med. 1993; (18): 1317-21
- Autopsy findings after coronary rotational atherectomy. Am J Cardiovasc Pathol. 1990; (4): 301-4
- Biosynthesis pathway of gp90MEL-14, the mouse lymph node-specific homing receptor. J Immunol. 1990; (5): 1477-82
- Mouse hematopoietic stem-cell antigen Sca-1 is a member of the Ly-6 antigen family. Proc Natl Acad Sci U S A. 1989; (12): 4634-8
- Mouse lymph node homing receptor cDNA clone encodes a glycoprotein revealing tandem interaction domains. Science. 1989; (4895): 1165-72
- Alloantigen recognition is preceded by nonspecific adhesion of cytotoxic T cells and target cells. Science. 1986; (4748): 403-5
- Isolation and purification of the human thymocyte antigens T6 and M241. Mol Immunol. 1986; (2): 131-9
- Association between the human thymic differentiation antigens T6 and T8. Eur J Immunol. 1985; (5): 529-32
- Beta 2-microglobulin from serum associates with MHC class I antigens on the surface of cultured cells. Nature. 1984 Apr 12-18; (5960): 642-5
- Human cutaneous dendritic cells express two glycoproteins T6 and M241 which are biochemically identical to those found on cortical thymocytes. Hum Immunol. 1984; (4): 201-10
- Recognition of HLA-A2 by cytotoxic T lymphocytes after DNA transfer into human and murine cells. Science. 1984; (4678): 1083-5
- Biochemical comparison of the T6 antigen and HLA-A,B antigens. Hum Immunol. 1983; (1): 13-30
- Expression of the major histocompatibility antigens HLA-A2 and HLA-B7 by DNA-mediated gene transfer. J Immunol. 1983; (4): 2032-7
- Localization of a gene controlling the expression of the human transferrin receptor to the region q12 leads to qter of chromosome 3. Cytogenet Cell Genet. 1983; (3): 525-31
- Structural and functional aspects of the T-cell differentiation antigens T3, T6, and T8. Haematol Blood Transfus. 1983: 440-6
- The thymic differentiation markers T6 and M241 are two unusual MHC class I antigens. J Immunol. 1983; (2): 851-5
Help
Trial Administration