Steven Artandi

Publications

• Telomerase modulates Wnt signalling by association with target gene chromatin. Park JI, Venteicher AS, Hong JY, Choi J, Jun S, Shkreli M, Chang W, Meng Z, Cheung P, Ji H, McLaughlin M, Veenstra TD, Nusse R, McCrea PD, Artandi SE. Nature. 2009; 460 (7251): 66-72
• Telomeres and telomerase in cancer. Artandi SE, Depinho RA. Carcinogenesis. 2009
• Telomere uncapping, chromosomes, and carcinomas. Batista LF, Artandi SE. Cancer Cell. 2009; 15 (6): 455-7
• TCAB1: driving telomerase to Cajal bodies. Venteicher AS, Artandi SE. Cell Cycle. 2009; 8 (9): 1329-31
• A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis. Venteicher AS, Abreu EB, Meng Z, McCann KE, Terns RM, Veenstra TD, Terns MP, Artandi SE. Science. 2009; 323 (5914): 644-8
• Stem cell aging and aberrant differentiation within the niche. Choi J, Artandi S. Cell Stem Cell. 2009; 5 (1): 6-8
• TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program. Choi J, Southworth LK, Sarin KY, Venteicher AS, Ma W, Chang W, Cheung P, Jun S, Artandi MK, Shah N, Kim SK, Artandi SE. PLoS Genet. 2008; 4 (1): e10
• Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly. Venteicher AS, Meng Z, Mason PJ, Veenstra TD, Artandi SE. Cell. 2008; 132 (6): 945-57
• Aging, graying and loss of melanocyte stem cells. Sarin KY, Artandi SE. Stem Cell Rev. 2007; 3 (3): 212-7
• DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse. Maser RS, Wong KK, Sahin E, Xia H, Naylor M, Hedberg HM, Artandi SE, DePinho RA. Mol Cell Biol. 2007; 27 (6): 2253-65
• Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo. Rajaraman S, Choi J, Cheung P, Beaudry V, Moore H, Artandi SE. Proc Natl Acad Sci U S A. 2007; 104 (45): 17747-52
• Telomerase flies the coop: the telomerase RNA component as a viral-encoded oncogene. Artandi SE, J Exp Med. 2006; 203 (5): 1143-5
• Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain. Middleman EJ, Choi J, Venteicher AS, Cheung P, Artandi SE. Mol Cell Biol. 2006; 26 (6): 2146-59
• Telomeres, telomerase, and human disease. Artandi SE, N Engl J Med. 2006; 355 (12): 1195-7
• Pathways connecting telomeres and p53 in senescence, apoptosis, and cancer. Artandi SE, Attardi LD. Biochem Biophys Res Commun. 2005; 331 (3): 881-90
• Conditional telomerase induction causes proliferation of hair follicle stem cells. Sarin KY, Cheung P, Gilison D, Lee E, Tennen RI, Wang E, Artandi MK, Oro AE, Artandi SE. Nature. 2005; 436 (7053): 1048-52
• Complex roles for telomeres and telomerase in breast carcinogenesis. Artandi SE, Breast Cancer Res. 2003; 5 (1): 37-41
• Constitutive telomerase expression promotes mammary carcinomas in aging mice. Artandi SE, Alson S, Tietze MK, Sharpless NE, Ye S, Greenberg RA, Castrillon DH, Horner JW, Weiler SR, Carrasco RD, DePinho RA. Proc Natl Acad Sci U S A. 2002; 99 (12): 8191-6
• Telomere shortening and cell fates in mouse models of neoplasia. Artandi SE, Trends Mol Med. 2002; 8 (1): 44-7
• A critical role for telomeres in suppressing and facilitating carcinogenesis. Artandi SE, DePinho RA. Curr Opin Genet Dev. 2000; 10 (1): 39-46
• Mice without telomerase: what can they teach us about human cancer? Artandi SE, DePinho RA. Nat Med. 2000; 6 (8): 852-5
• Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Artandi SE, Chang S, Lee SL, Alson S, Gottlieb GJ, Chin L, DePinho RA. Nature. 2000; 406 (6796): 641-5
• p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Chin L, Artandi SE, Shen Q, Tam A, Lee SL, Gottlieb GJ, Greider CW, DePinho RA. Cell. 1999; 97 (4): 527-38