Feng Lan

Publications

• Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. Lan F, Lee AS, Liang P, Sanchez-Freire V, Nguyen PK, Wang L, Han L, Yen M, Wang Y, Sun N, Abilez OJ, Hu S, Ebert AD, Navarrete EG, Simmons CS, Wheeler M, Pruitt B, Lewis R, Yamaguchi Y, Ashley EA, Bers DM, Robbins RC, Longaker MT, Wu JC. Cell Stem Cell. 2013; 12 (1): 101-13
• Drug Screening Using a Library of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Reveals Disease Specific Patterns of Cardiotoxicity Liang P*, Lan F*, Lee AS*, Gong T, Sanchez-Freire V, Wang Y, Diecke S, , Sallam K, Knowles JW, Nguyen PK, Wang PJ, Bers DM, Robbins RC, Wu JC(*Equal contribution). Circulation. 2013
• Early stem cell engraftment predicts late cardiac functional recovery: preclinical insights from molecular imaging Liu J*, Narsinh KH*, Lan F*, Wang L, Nguyen PK, Hu S, Lee A, Han L, Gong Y, Huang M, Nag D, Rosenberg J, Chouldechova A, Robbins RC, Wu JC. (*Equal contribution). Circ Cardiovasc Imaging. 2012; 5 (4): 481-90
• Safe genetic modification of cardiac stem cells using a site-specific integration technique. Lan F, Liu J, Narsinh KH, Hu S, Han L, Lee AS, Karow M, Nguyen PK, Nag D, Calos MP, Robbins RC, Wu JC. Circulation. 2012; 126 (11 Suppl 1): S20-8
• Inducible expression of stem cell associated intermediate filament nestin reveals an important role in glioblastoma carcinogenesis Lu WJ*, Lan F*, He Q, Lee A, Tang CZ, Dong L, Lan B, Ma X, Wu JC, Shen L (*Equal contribution). Int J Cancer. 2011; 128 (2): 343-51
• Short-term immunosuppression promotes engraftment of embryonic and induced pluripotent stem cells. Pearl JI, Lee AS, Leveson-Gower DB, Sun N, Ghosh Z, Lan F, Ransohoff J, Negrin RS, Davis MM, Wu JC. Cell Stem Cell. 2011; 8 (3): 309-17
• MicroRNA-302 increases reprogramming efficiency via repression of NR2F2. Hu S, Wilson KD, Ghosh Z, Han L, Wang Y, Lan F, Ransohoff KJ, Burridge P, Wu JC. Stem Cells. 2013; 31 (2): 259-68
• Role of SIRT6 in Aging and Reprogramming of Human Induced Pluripotent Stem Cells. Sharma A, Diecke S, Zhang WY, Lan F, He C, Mordwinkin NM, Chua KF, Wu JC. J Biol Chem. 2013
• Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging. Wang Y, Zhang WY, Hu S, Lan F, Lee AS, Huber B, Lisowski L, Liang P, Huang M, de Almeida PE, Won JH, Sun N, Robbins RC, Kay MA, Urnov FD, Wu JC. Circ Res. 2012; 111 (12): 1494-503
• Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair. Mohsin S, Khan M, Toko H, Bailey B, Cottage CT, Wallach K, Nag D, Lee A, Siddiqi S, Lan F, Fischer KM, Gude N, Quijada P, Avitabile D, Truffa S, Collins B, Dembitsky W, Wu JC, Sussman MA. J Am Coll Cardiol. 2012; 60 (14): 1278-87
• Imaging: guiding the clinical translation of cardiac stem cell therapy. Nguyen PK, Lan F, Wang Y, Wu JC. Circ Res. 2011; 109 (8): 962-79
• Induction of mutant p53-dependent apoptosis in human hepatocellular carcinoma by targeting stress protein mortalin. Lu WJ, Lee NP, Kaul SC, Lan F, Poon RT, Wadhwa R, Luk JM. Int J Cancer. 2011; 129 (8): 1806-14
• Mortalin-p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy. Lu WJ, Lee NP, Kaul SC, Lan F, Poon RT, Wadhwa R, Luk JM. Cell Death Differ. 2011; 18 (6): 1046-56
• Novel microRNA prosurvival cocktail for improving engraftment and function of cardiac progenitor cell transplantation. Hu S, Huang M, Nguyen PK, Gong Y, Li Z, Jia F, Lan F, Liu J, Nag D, Robbins RC, Wu JC. Circulation. 2011; 124 (11 Suppl): S27-34
• Preclinical derivation and imaging of autologously transplanted canine induced pluripotent stem cells. Lee AS, Xu D, Plews JR, Nguyen PK, Nag D, Lyons JK, Han L, Hu S, Lan F, Liu J, Huang M, Narsinh KH, Long CT, de Almeida PE, Levi B, Kooreman N, Bangs C, Pacharinsak C, Ikeno F, Yeung AC, Gambhir SS, Robbins RC, Longaker MT, Wu JC. J Biol Chem. 2011; 286 (37): 32697-704
• Site-specific recombinase strategy to create induced pluripotent stem cells efficiently with plasmid DNA. Karow M, Chavez CL, Farruggio AP, Geisinger JM, Keravala A, Jung WE, Lan F, Wu JC, Chen-Tsai Y, Calos MP. Stem Cells. 2011; 29 (11): 1696-704
• Generation of human-induced pluripotent stem cells from gut mesentery-derived cells by ectopic expression of OCT4/SOX2/NANOG. Li Y, Zhao H, Lan F, Lee A, Chen L, Lin C, Yao Y, Li L. Cell Reprogram. 2010; 12 (3): 237-47
• Overexpression of CD133 promotes the phosphorylation of Erk in U87MG human glioblastoma cells. Dong L, Qi N, Ge RM, Cao CL, Lan F, Shen L. Neurosci Lett. 2010; 484 (3): 210-4
• Adenovirus-mediated CTLA4Ig gene transfer improves the survival of grafted human hepatic progenitors in mouse liver. Lan F, Ma X, Liu Y, Shen I. Transplant Proc. 2009; 41 (5): 1862-4
• Hepatocyte growth factor promotes proliferation and migration in immortalized progenitor cells. Lan F, Xu J, Zhang X, Wong VW, Li X, Lu A, Lu W, Shen L, Li L. Neuroreport. 2008; 19 (7): 765-9
• In vivo gamma imaging of the secondary tumors of transplanted human fetal striatum neural stem cells-derived primary tumor cells. He Q, Liu Z, Jia B, Li X, Shi J, Zhang J, Lan F, Yang Z, Liu Y, Shen L, Wang F. Neuroreport. 2008; 19 (10): 1009-14