Stanford Medicine
Cancer Center A Cancer Center Designated by
the National Cancer Institute

Department: Cancer Center

Division: Radiation Biology

  • Faculty (29)
  • Postdocs (0)
  • All
  • Academic Appointments
    • Associate Professor, Radiation Oncology - Radiation Biology
    • Associate Professor, Genetics
    • Member, Bio-X
    • Member, Cancer Center
    Research Interest

    Our research is aimed at defining the pathways of p53-mediated apoptosis and tumor suppression, using a combination of biochemical, cell biological, and mouse genetic approaches. Our strategy is to start by generating hypotheses about p53 mechanisms of action using primary mouse embryo fibroblasts (MEFs), and then to test them using gene targeting technology in the mouse.

  • Academic Appointments
    • Professor - Med Center Line, Comparative Medicine
    • Professor - Med Center Line (By courtesy), Pathology
    • Member, Cancer Center
    Research Interest

    Research interests: ocular pathology, host-pathogen interactions in infectious disease, infectious disease in frogs, phenotypic characterization of tg and ko mice, histopathology of minimally-invasive radiological ablation techniques (focused ultrasound, cryoablation).

  • Academic Appointments
    • Professor, Radiation Oncology - Radiation Biology
    • Member, Cancer Center
    Research Interest

    We seek to understand the mechanisms responsible for the resistance of cancers to treatment and to develop strategies to overcome these resistances. We are using molecular and cellular techniques and mouse models to exploit tumor hypoxia with drugs activated by hypoxia and anaerobic bacteria as tumor-specific gene therapy vectors. We are also testing ways of inhibiting the bone marrow rescue of the tumor vasculature following therapy.

  • Academic Appointments
    • Member, Cancer Center
  • Academic Appointments
    • Assistant Professor, Bioengineering
    • Member, Bio-X
    • Member, Cancer Center
    Research Interest

    Molecular Bioengineering, Protein Biochemistry and Biotechnology, Cell and Tissue Engineering, Molecular Imaging

  • Academic Appointments
    • Professor, Pediatrics - Pulmonary Medicine
    • Member, Cancer Center
    Clinical Focus
    • Pediatric Pulmonary
    • Pulmonary Medicine/Cystic Fibrosis, Pediatric
  • Academic Appointments
    • Assistant Professor, Radiation Oncology - Radiation Biology
    • Member, Cancer Center
    Research Interest

    We are interested in the biologic effect of gene expression changes that occur in the solid tumor. Many of these expression changes are due to the micro-physiology within the tumor. Several of these genes have been implicated in driving malignant progression and/or regulating response to therapeutic intervention. We hope to use these molecular changes to develop novel targeted therapies that take advantage of tumor specific gene expression changes.

  • Academic Appointments
    • Professor, Radiation Oncology - Radiation Therapy
    • Member, Cancer Center
    Clinical Focus
    • Basal / Squamous Cell Carcinomas - Radiation Oncology
    • Bone Cancer
    • Brain / Central Nervous System Tumors
    Research Interest

    Combined Modality Treatment of Cancer Late Effects of Treatment Genetic Effects of Cancer Rhabdomyosarcoma Hodgkins Disease Pediatric Radiation Oncolgy Pediatric Oncolgy Breast Cancer Conformal Radiotherapy/IMRT Radiotherapy for Benign Diseases

  • Academic Appointments
    • Associate Professor, Medicine - Oncology
    • Associate Professor, Genetics
    • Associate Professor (By courtesy), Pediatrics
    • Member, Bio-X
    • Member, Cancer Center
    Clinical Focus
    • Cancer Genetics
    • Gastrointestinal Cancers - Genetics
    • Gastrointestinal Cancers - Medical Oncology
    Research Interest

    Mammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNA damage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer.

  • Academic Appointments
    • Professor, Radiation Oncology - Radiation Biology
    • Professor (By courtesy), Obstetrics & Gynecology
    • Professor (By courtesy), Surgery
    • Member, Cancer Center
    Research Interest

    Cellular response to hypoxia and ionizing radiation; cell-cycle control, apoptosis and angiogenesis in transformed cells.

  • Academic Appointments
    • Associate Professor - Med Center Line, Radiation Oncology - Radiation Therapy
    • Member, Cancer Center
    Clinical Focus
    • Cyberknife
    • Brain / Central Nervous System Tumors - Radiation Oncology
    • Acoustic Neuroma
    Research Interest

    Dr. Gibbs is a board-certified radiation oncologist who specializes in the treatment of CNS tumors. Her research focuses on developing new radiation techniques to manage brain and spinal tumors in adults and children. Dr. Gibbs has gained worldwide acclaim for her expertise in Cyberknife robotic radiosurgery.

  • Academic Appointments
    • Assistant Professor, Radiation Oncology - Radiation Physics
    • Member, Cancer Center
    Research Interest

    Applications of molecular imaging in radiation therapy, development of hypoxia and radiosensitivity imaging techniques, image processing and analysis.

  • Academic Appointments
    • Professor - Med Center Line, Surgery - Plastic/Recon Surgery
    • Member, Cancer Center
    Clinical Focus
    • Plastic Surgery
    Research Interest

    Geoffrey Gurtner's Lab is interested in understanding the mecahnism of new blood vessel growth following injury and how pathways of tissue regeneration and fibrosis interact in wound healing.

  • Academic Appointments
    • Professor, Biology (School of Humanities and Sciences)
    • Professor, Dermatology
    • Member, Bio-X
    • Member, Cancer Center
    Research Interest

    Hanawalt has been a productive researcher in the field of DNA repair since his pioneering discovery of repair replication in E. coli in 1963. He also first demonstrated repair replication in mycoplasmata and in a eukaryote and he has developed a number of important experimental approaches for studying repair, beginning with the BrdUrd density labeling method for resolving semiconservatively replicated DNA from parental DNA containing repair patches. Hanawalt’s approach was used to validate the ..

  • Academic Appointments
    • Professor, Radiation Oncology - Radiation Therapy
    • Member, Cancer Center
    Clinical Focus
    • Lymphoma
    • Cutaneous Lymphoma
    • Cutaneous Lymphoma - Radiation Oncology
    Research Interest

    Irradiation immunosuppression; total body irradiation;, psychosocial effects of cancer treatment; treatment of lymphoma;, mycosis fungoides.

  • Academic Appointments
    • Professor, Radiation Oncology - Radiation Therapy
    • Member, Cancer Center
    Clinical Focus
    • Brain / Central Nervous System Tumors
    • Brain / Central Nervous System Tumors - Radiation Oncology
    • Breast Cancer
    Research Interest

    Gynecologic malignancies; Rectal/and cancer; Breast Cancer; Hodgkin's disease; Hyperthermia; intraoperative radiation therapy; High dose rate radiation therapy; Predictive assays; Patterns of tumor spread; Health care finance.

  • Academic Appointments
    • Member, Cancer Center
    Research Interest

    Prostate cancer

  • Academic Appointments
    • Associate Professor, Radiation Oncology - Radiation Therapy
    • Member, Bio-X
    • Member, Cancer Center
    Clinical Focus
    • Radiation Oncology
    • Radiation Therapy
    Research Interest

    Our interests in clude 1) study of the effect of radiation on regulatory cell subpopulations and co-stimulatory molecules, 2) use of radiation as an immune modulator for optimization of transplant regimens, and 3) the role of radiation in tumor vaccine strategies.

  • Academic Appointments
    • Assistant Professor, Radiation Oncology - Radiation Therapy
    • Member, Bio-X
    • Member, Cancer Center
    Clinical Focus
    • Colorectal Cancer
    • Colorectal Cancer - Radiation Oncology
    • Esophageal Cancer
    Research Interest

    The focus of my laboratory is to understand the role of hypoxia and the tumor microenvironment on malignant progression. My clinical area of interest is in the application of chemoradiotherapy and stereotactic radiosurgery for GI maligancies

  • Academic Appointments
    • Associate Professor (Research), Psychiatry & Behavioral Science
    • Associate Professor (Research), Pediatrics
    • Member, Bio-X
    • Member, Cancer Center
  • Academic Appointments
    • Professor - Med Center Line, Radiation Oncology - Radiation Therapy
    • Professor - Med Center Line (By courtesy), Otolaryngology (Head and Neck Surgery)
    • Member, Bio-X
    • Member, Cancer Center
    Clinical Focus
    • Head and Neck Cancers
    • Head and Neck Cancers - Radiation Oncology
    • Larynx Cancer
    Research Interest

    My laboratory research interest focusses on the identification of serum markers for tumor hypoxia and for prognosis in patients with head and neck or lung cancers. I am also conducting a number of clinical trials specifically in patients with these tumors.

  • Academic Appointments
    • Professor, Surgery - Plastic/Recon Surgery
    • Professor (By courtesy), Bioengineering
    • Member, Bio-X
    • Member, Cancer Center
    Clinical Focus
    • Plastic Surgery
    • Plastic Surgery, Pediatric
    Research Interest

    We have six main areas of current interest: 1) Cranial Suture Developmental Biology, 2)Distraction Osteogenesis, 3) Cleft Palate and Lip Biology, 4)Keloid and Hypertrophic Scar Biology, 5) Scarless Fetal Wound Healing, 6) Novel Gene and Stem Cell Therapeutic Approaches.

  • Academic Appointments
    • Acting Assistant Professor, Radiation Oncology - Radiation Therapy
    • Member, Bio-X
    • Member, Cancer Center
    Clinical Focus
    • Radiation Oncology
    • Radiation Therapy
    • Lung Cancer
    Research Interest

    My main clinical specialties are radiation treatment of lung cancer and head & neck cancer, and I serve as the thoracic radiation oncology program leader. My research interests include 4-D multimodality imaging to capture and compensate for breathing-induced motion using CT, PET, and MR; novel functional/metabolic imaging methods to characterize tumor biology; high-precision image-guided radiation therapy including 4-D IMRT, dynamic arc therapy, and radiosurgery.

  • Academic Appointments
    • Professor, Medicine - Oncology
    • Professor (By courtesy), Chemical and Systems Biology
    • Member, Cancer Center
    Clinical Focus
    • Hematology
    Research Interest

    Beverly Mitchell's research relates to the development of new therapies for hematologic malignancies. She has a long-standing interest in IMPDH as a therapeutic target and has published extensively on the regulation of this enzyme and the potential role of inhibitors in the treatment of leukemia in preclinical studies.

  • Academic Appointments
    • Assistant Professor, Biology (School of Humanities and Sciences)
    • Member, Cancer Center
    Research Interest

    Our research interests are to elucidate the contribution of chromatin to mechanisms that promote genomic integrity.

  • Academic Appointments
    • Professor (Research), Urology
    • Member, Bio-X
    • Member, Cancer Center
    Research Interest

    My research focuses on the molecular and cellular biology of the human prostate. Developing realistic experimental models is a major goal, and primary cultures of prostatic epithelial and stromal cells are my main model system. Our discoveries are relevant to prevention, detection, diagnosis and treatment of benign and malignant prostatic diseases.

  • Academic Appointments
    • Member, Cancer Center
    Research Interest

    Breast cancer; three-dimensional treatment planning; community patterns of care and technology transfer.

  • Academic Appointments
    • Professor, Health Research & Policy - Biostatistics
    • Professor, Statistics
    • Member, Bio-X
    • Member, Cancer Center
    Research Interest

    My research is in applied statistics and biostatistics. I specialize in computer-intensive methods for regression and classification, bootstrap, cross-validation and statistical inference, and signal and image analysis for medical diagnosis.

  • Academic Appointments
    • Professor, Radiation Oncology - Radiation Physics
    • Member, Bio-X
    • Member, Cancer Center
    Research Interest

    Image-guided intervention, MR spectroscopic imaging (MRSI) and radionuclide imaging (PET/CT, SPECT/CT), biologically conformable radiation threapy (BCRT), intensity modulated radiation therapy (IMRT), treatment plan optimization, optimization of stereotactic radiosurgery, image segmentation and deformable image registration, application of molecular imaging to radiation oncology.

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