Cancer Institute A national cancer institute
designated cancer center

Department: Stanford Cancer Institute

Division: Hematopoietic Cell Transplant

  • All Profiles
  • Faculty
  • Postdocs
  • Staff
  • Academic Appointments Assistant Professor - Med Center Line,  Medicine - Blood & Marrow Transplantation
    Member,  Stanford Cancer Institute
    Clinical Focus
    • Cancer  >  Blood and Marrow Transplant
    • Cancer  >  Hematology
    • Blood and Marrow Transplantation
    Research Interest

    Research interest in utilizing post-transplant adoptive cellular immunotherapy to reduce GVHD and relapse in patients with high risk hematologic malignancies.

  • Academic Appointments Professor,  Pediatrics - Infectious Diseases
    Member,  Child Health Research Institute
    Member,  Stanford Cancer Institute
    Professor,  Microbiology & Immunology
    Clinical Focus
    • Infectious Diseases, Pediatric
    • Pediatric Infectious Disease
    Research Interest

    Our laboratory investigates the pathogenesis of varicella zoster virus (VZV) infection, focusing on the functional roles of particular viral gene products in pathogenesis and virus-cell interactions in differentiated human cells in humans and in Scid-hu mouse models of VZV cell tropisms in vivo, and the immunobiology of VZV infections.

  • Academic Appointments Professor - Med Center Line,  Medicine - Blood & Marrow Transplantation
    Member,  Stanford Cancer Institute
    Clinical Focus
    • Cancer  >  Blood and Marrow Transplant
    • Blood and Marrow Transplantation
    • Blood and Marrow Transplantation / Infectious Diseases
  • Academic Appointments Member,  Stanford Cancer Institute
    Member,  Bio-X
    Clinical Focus
    • Intensive Care, Pediatric
    • Pediatric Critical Care Medicine
    Research Interest

    Hemofiltration and survival in respiratory failure after bone marrow transplantation. A randomized, controlled multi – center trial. J. DiCarlo, principal investigator. Stanford University IRB #3, Protocol #78861. Pediatric Health Research Grant, Department of Pediatrics, Stanford University (03/2003 – 09/2004), and Leukemia & Lymphoma Society Translational Research Grant #6090-05 [J. DiCarlo (PI), 10/2004 – 09/2007]. Proteomic analysis of ultrafiltrate and serum in ARDS after transplantati..

  • Academic Appointments Professor Emeritus,  Medicine - Hematology
    Emeritus Faculty, Acad Council,  Medicine - Hematology
    Member,  Stanford Cancer Institute
    Member,  Bio-X
    Clinical Focus
    • Cancer  >  Hematology
    • Hematology
    • Myelodysplastic Syndromes
    Research Interest

    Regulation of hematopoiesis in myeloid malignancies with special emphasis on myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Laboratory studies utilize DNA microarrays to determine differential gene expression in MDS and AML. Transcriptomic abnormalities are also being evaluated using RNA-Seq and proteomic technologies. Translational clinical studies focus on using specific biologic targeting agents to treat these disorders.

  • Academic Appointments Associate Professor - Med Center Line,  Medicine - Blood & Marrow Transplantation
    Member,  Stanford Cancer Institute
    Clinical Focus
    • Cancer  >  Blood and Marrow Transplant
    • Cancer  >  Hematology
    • Blood and Marrow Transplantation
    Research Interest

    Clinical research in allogeneic and autologous hematopoietic cell transplantation (HCT), more specifically, allogeneic transplantation and graft versus host disease. Exploring methods of improving prevention and treatment of GVHD as well as the long term follow-up and/or quality of life of affected patients.

  • Academic Appointments Associate Professor - Med Center Line,  Medicine - Blood & Marrow Transplantation
    Member,  Stanford Cancer Institute
    Clinical Focus
    • Cancer  >  Blood and Marrow Transplant
    • Cancer  >  Hematology
    • Blood and Marrow Transplantation
    Research Interest

    haploidentical transplantation, follicular lymphoma, adoptive immunotherapy,supportive care

  • Research Interest

    Biostatistics, clinical trials, longitudinal studies, casual inference from observational studies, genetic tissue banking, informed consent. Trial designs for dynamic (adaptive) treatment regimes, psychiatric research, cancer.

  • Academic Appointments Associate Professor - Med Center Line,  Medicine - Blood & Marrow Transplantation
    Member,  Stanford Cancer Institute
    Clinical Focus
    • Cancer  >  Blood and Marrow Transplant
    • Cancer  >  Hematology
    • Blood and Marrow Transplantation
    Research Interest

    Dr. Lowsky's research is focused on understanding the role of regulatory T cells in the prevention of GVHD and in promoting immune tolerance following organ transplantation.

  • Academic Appointments Assistant Professor - Med Center Line,  Medicine - Blood & Marrow Transplantation
    Member,  Stanford Cancer Institute
    Clinical Focus
    • Cancer  >  Blood and Marrow Transplant
    • Cancer  >  Hematology
    • Aplastic Anemia
    Research Interest

    Investigates the targets of immune responses after human allogeneic stem cell transplantation. BMT patients develop antibodies against minor histocompatibility antigens (mHA) that are associated with chronic graft-v-host disease (cGVHD) and disease remission. Current projects: investigate Ab anti-tumor mechanism, high-throughput serologic identification of novel mHA in the development of GVHD and prevention of disease relapse, and clinical trials of B cell therapeutics for cGVHD.

  • Clinical Focus
    • Cancer  >  Blood and Marrow Transplant
    • Cancer  >  Hematology
    • Blood and Marrow Transplantation
    Research Interest

    Our labaratory focuses on the study of immune recognition by T and NK cells with special emphasis on graft vs host disease and graft vs tumor reactions. We utilize both murine and human systems in an effort to enhance graft vs tumor reactions while controlling graft vs host disease. We have developed bioluminescence models in collaboration with the Contag laboratory to study the trafficking of immune effector cells with a special emphasis on NK, T and regulatory T cells.

  • Academic Appointments Member,  Stanford Cancer Institute
    Clinical Focus
    • Oncology
    • Oncology (Cancer)
  • Academic Appointments Professor,  Structural Biology
    Member,  Stanford Cancer Institute
    Professor,  Microbiology & Immunology
    Research Interest

    The Parham laboratory investigates the biology, genetics, and evolution of MHC class I molecules and NK cell receptors.

  • Academic Appointments Associate Professor,  Medicine - Blood & Marrow Transplantation
    Member,  Stanford Cancer Institute
    Clinical Focus
    • Cancer  >  Blood and Marrow Transplant
    • Blood and Marrow Transplantation
    • Hematology
    Research Interest

    Transplantation of defined populations of allogeneic hematopoietic cells. Specifically, the way in which hematopoietic cell grafts alter antigen specific immune responses to allo-, auto- and viral antigens. The cellular and molecular basis of resistance to engraftment of allogeneic hematopoietic stem cells.

  • Academic Appointments Professor,  Medicine - Immunology & Rheumatology
    Member,  Stanford Cancer Institute
    Clinical Focus
    • Immunology and Rheumatology
    • Rheumatology
    Research Interest

    Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation.

  • Clinical Focus
    • Hematology, Pediatric
    • Oncology (Cancer), Pediatric
    • Pediatric Hematology-Oncology

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