Seiji Nishino
Academic Appointments
- Professor (Research), Psychiatry & Behavioral Science - Sleep Center
Key Documents
Contact Information
- Academic Offices
Personal Information Email Tel (650) 213-8605 Tel (650) 213-8600
Scientific Focus
Current Research Interests
The research focus of the Sleep and Circadian Neurobiology (SCN) Laboratory is the study of the sleep and circadian physiology using various animal models. A portion of the research is carried out using rodent models of narcolepsy and circadian rhythm sleep disorders. The laboratory also carries out pharmacological studies aiming to develop new treatments for these sleep disorders.
Publications
- Hypocretin/orexin and narcolepsy: new basic and clinical insights. Acta Physiol (Oxf). 2010; (3): 209-22
- Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle. Science. 2009; (5955): 1005-7
- CSF histamine contents in narcolepsy, idiopathic hypersomnia and obstructive sleep apnea syndrome. Sleep. 2009; (2): 181-7
- Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls. Sleep. 2009; (2): 175-80
- Orexin neurons are necessary for the circadian control of REM sleep. Sleep. 2009; (9): 1127-34
- Specificity of direct transition from wake to REM sleep in orexin/ataxin-3 transgenic narcoleptic mice. Exp Neurol. 2009; (1): 46-54
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