My laboratory focuses on merging advances in molecular biology with those in biomedical imaging to advance the new field of molecular imaging. Methods to image gene expression in living subjects have been developed. Newer approaches to image fundamental cellular events with optical and radiolabeled probes are under active investigation. These imaging approaches are expected to have a fundamental impact in the study of cancer biology, as well as in molecular therapeutics including gene therapy

• Goerke AR, Loening AM, Gambhir SS, Swartz JR "Cell-free metabolic engineering promotes high-level production of bioactive Gaussia princeps luciferase." Metab Eng 2008 May-Jul; 10: 3-4: 187-200 More
• Willmann JK, Paulmurugan R, Chen K, Gheysens O, Rodriguez-Porcel M, Lutz AM, Chen IY, Chen X, Gambhir SS "US Imaging of Tumor Angiogenesis with Microbubbles Targeted to Vascular Endothelial Growth Factor Receptor Type 2 in Mice." Radiology 2008; More
• Chan CT, Paulmurugan R, Gheysens OS, Kim J, Chiosis G, Gambhir SS "Molecular imaging of the efficacy of heat shock protein 90 inhibitors in living subjects." Cancer Res 2008; 68: 1: 216-26 More
• Massoud TF, Singh A, Gambhir SS "Noninvasive Molecular Neuroimaging Using Reporter Genes: Part II, Experimental, Current, and Future Applications." AJNR Am J Neuroradiol 2008; More
• Willmann JK, Chen K, Wang H, Paulmurugan R, Rollins M, Cai W, Wang DS, Chen IY, Gheysens O, Rodriguez-Porcel M, Chen X, Gambhir SS "Monitoring of the Biological Response to Murine Hindlimb Ischemia With 64Cu-Labeled Vascular Endothelial Growth Factor-121 Positron Emission Tomography." Circulation 2008; More