Pehr Harbury
Academic Appointments
- Associate Professor, Biochemistry
- Member, Bio-X
- Member, Cancer Center
Scientific Focus
Research Interests
Our lab engineers proteins and small-molecule drugs at atomic resolution through a combination of structural calculations and combinatorial library synthesis. Our goal is to elucidate predictive principles by which novel shapes and catalytic properties can be conferred accurately on designed polypeptides.
Publications
- Remeasuring the double helix. Science. 2008; (5900): 446-9
- A molecular ruler for measuring quantitative distance distributions. PLoS One. 2008; (10): e3229
- Design of protein-ligand binding based on the molecular-mechanics energy model. J Mol Biol. 2008; (2): 415-24
- Potential energy functions for protein design. Curr Opin Struct Biol. 2007; (2): 199-204
- Chemical evolution as a tool for molecular discovery. Annu Rev Biochem. 2007: 331-49
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