Professional Snapshot
Professional Education
| Doctor of Philosophy: | California Institute of Technology, (2007) |
Faculty Advisor
Scientific Focus
Publications
- Arginine coordination in enzymatic phosphoryl transfer: evaluation of the effect of Arg166 mutations in Escherichia coli alkaline phosphatase. Biochemistry. 2008; (29): 7663-72
- Promiscuous sulfatase activity and thio-effects in a phosphodiesterase of the alkaline phosphatase superfamily. Biochemistry. 2008; (48): 12853-9
- Full-sequence computational design and solution structure of a thermostable protein variant. J Mol Biol. 2007; (1): 1-6
- Exhaustive mutagenesis of six secondary active-site residues in Escherichia coli chorismate mutase shows the importance of hydrophobic side chains and a helix N-capping position for stability and catalysis. Biochemistry. 2007; (23): 6883-91
- Combinatorial methods for small-molecule placement in computational enzyme design. Proc Natl Acad Sci U S A. 2006; (45): 16710-5
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