Clinical treatment trials in Breast Cancer, especially locally recurrent breast cancer. She is chair of multicenter national trial investigating the optimal systemic treatment for women who develop a local or regional recurrence of breast cancer after mastectomy or lumpectomy. Additinally, Dr. Wapnir is institutional Principal Investigator for National Surgical Adjuvant Breast and Bowel Project (NSABP). Her basic and preclinical research centers on exploring the activity of breast sodium-iodide transporter (NIS) in breast cancer. Translational research protocols elucidating the potential application of NIS-based therapies are ongoing.

• Madrigrano A, Westphal L, Wapnir I "Egg retrieval with cryopreservation does not delay breast cancer treatment." Am J Surg 2007; 194: 4: 477-81 More
• Ghosh M, Gambhir SS, De A, Nowels K, Goris M, Wapnir I "Bioluminescent monitoring of NIS-mediated (131)I ablative effects in MCF-7 xenografts." Mol Imaging 2006 Apr-Jun; 5: 2: 76-84 More
• Wapnir IL, Anderson SJ, Mamounas EP, Geyer CE, Jeong JH, Tan-Chiu E, Fisher B, Wolmark N "Prognosis after ipsilateral breast tumor recurrence and locoregional recurrences in five National Surgical Adjuvant Breast and Bowel Project node-positive adjuvant breast cancer trials." J Clin Oncol 2006; 24: 13: 2028-37 More
• Samiian L, Daniel B, Wapnir I "Resolution of hypoalbuminemia after excision of malignant phyllodes tumor." Clin Breast Cancer 2006; 7: 5: 411-2 More
• Wapnir IL, Goris M, Yudd A, Dohan O, Adelman D, Nowels K, Carrasco N "The Na+/I- symporter mediates iodide uptake in breast cancer metastases and can be selectively down-regulated in the thyroid." Clin Cancer Res 2004; 10: 13: 4294-302 More