Griffith Harsh

Clinical Focus

• Cancer > Neuro Oncology
• Acoustic Neuroma
• Acoustic Neuroma - Head and Neck Surgery
• Brain / Central Nervous System Tumors
• Brain / Central Nervous System Tumors - Neuro Oncology

Administrative Appointments

• Program Director, Stanford Neurosurgery Resident Training Program (2004 - 2006)
• Surgical Director, Stanford Pituitary Center (2004 - 2006)
• Director, Stanford Surgical Neuro-oncology (1998 - 2006)

Honors and Awards

• Excellence in Resident Teaching, Stanford Neurosurgery (2000)
• Outstanding Teacher Award, MGH Neurosurgery (1994)
• Golden Amygdala Teaching Award, UCSF Neurosurgery (1990)
• Rhodes Scholarship, Rhodes Trust (1975-1978)

Professional Education

Graduate & Fellowship Program Affiliations

• Cancer Biology
• Neurobiology
• Neurosurgery

Research Interests

Microsurgical treatment of tumors of the brain, spinal cord, pituitary gland and skull base;
Radiosurgery of tumors;
Molecular biology of brain tumors.

Clinical Trials

• Phase I Vorinostat Concurrent with Stereotactic Radiosurgery (SRS) in Brain Metastases from Non-Small Cell Lung Cancer Recruiting
• Phase I/II Study of Fractionated Stereotactic Radiosurgery to Treat Large Brain Metastases Recruiting
• An Open-Labeled, Extended-Use of XERECEPT (hCRF) for Patients in Studies NTI 0302, 0303, or Other Designated Studies Completed
• Phase I Trial of Arsenic Trioxide and Stereotactic Radiotherapy for Recurrent Malignant Glioma Completed
• XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors Completed

Publications

• Predictors of peritumoral edema after stereotactic radiosurgery of supratentorial meningiomas. Patil CG, Hoang S, Borchers DJ, Sakamoto G, Soltys SG, Gibbs IC, Harsh GR, Chang SD, Adler JR. Neurosurgery. 2008; 63 (3): 435-40; discussion 440-2
• National trends, complications, and outcomes following transsphenoidal surgery for Cushing's disease from 1993 to 2002. Patil CG, Lad SP, Harsh GR, Laws ER, Boakye M. Neurosurg Focus. 2007; 23 (3): E7
• Efficacy and safety of CyberKnife radiosurgery for acromegaly. Roberts BK, Ouyang DL, Lad SP, Chang SD, Harsh GR, Adler JR, Soltys SG, Gibbs IC, Remedios L, Katznelson L. Pituitary. 2007; 10 (1): 19-25
• Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappaB-mediated resistance to O6-alkylating agents in human glioblastomas. Bredel M, Bredel C, Juric D, Duran GE, Yu RX, Harsh GR, Vogel H, Recht LD, Scheck AC, Sikic BI. J Clin Oncol. 2006; 24 (2): 274-87
• High-resolution genome-wide mapping of genetic alterations in human glial brain tumors. Bredel M, Bredel C, Juric D, Harsh GR, Vogel H, Recht LD, Sikic BI. Cancer Res. 2005; 65 (10): 4088-96