Garry Nolan
Academic Appointments
- Professor, Microbiology & Immunology - Baxter Laboratory
- Member, Bio-X
- Member, Stanford Cancer Institute
Key Documents
Contact Information
- Academic Offices
Personal Information Email Tel (650) 725-7002Alternate Contact Howard Guss Administrative Associate / Office Manager Email Tel Work 650-725-7002
Professional Overview
Administrative Appointments
- NCI-Frederick Advisory Committee, NCI (2011 - 2015)
- Board of External Experts, National Heart, Lung, and Blood Institute of the NIH (2007 - present)
- Director, Stanford NHLBI Proteomics Center, National Heart, Lung, and Blood Institute of the NIH (2010 - 2015)
Honors and Awards
- Teal Innovator Award, Department of Defense (2012-2017)
- Outstanding Research Achievement, for Mass Cytometry and CyTOF, Nature Publishing Group (2011)
- Stohlman Scholar, Leukemia and Lymphoma Society (2000)
- Scholar of the Leukemia Society, Leukemia and Lymphoma Society (1996-2000)
- Burrough's Wellcome Investigator's Award In Pharmacology, Burroughs Wellcome (1995-2000)
Professional Education
| B.S.: | Cornell University, Genetics (1983) |
| Ph.D.: | Stanford University, Genetics (1989) |
| Postdoctoral Fellowship: | MIT, David Baltimore Laboratory, Biochemistry (1993) |
Postdoctoral Advisees
Nima Aghaee Pour, robert Angelo, Gregory Behbehani, Sean Bendall, Shih-Yu Chen, Tiffany Chen, Andreas Frei, Pier Federico Gherardini, Veronica Gonzalez Munoz, Christina Loh, Nikolay Samusik, Eli Zunder
Graduate & Fellowship Program Affiliations
Internet Links
Industry Relationships
Stanford is committed to ethical and transparent interactions with our industrial and other commercial partners. It is our policy to disclose payments (exclusive of travel support) from, and/or equity in, companies or other commercial entities to Stanford faculty of $5,000 or more in total value, as well as any equity in a privately held company, when the faculty member also has institutional responsibilities related to his or her interactions with the company. View Full Information
Scientific Focus
Current Research Interests
Our areas of expertise include signal transduction, immunology, cancer biology, retroviral design, bioinformatics and genetics. Our laboratorys recent interests include studying signaling alterations at the single cell level in leukemia and lymphomas, cancer stem cells, and determining which of these signaling attributes correlate with patient outcome, drug reactivity and mechanism of disease progressions. The lab also works on global representations of signaling attributes and capabilities in the immune system in autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. Our lab develops and applies advanced tools in informatics, such as machine learning, as implemented specifically for single cell analysis and use of perturbation analysis.
We put substantial effort into bioinformatics approaches to mine the datasets we collect and to automate the production of network models of the signaling pathways affected. For this, we have collaborations with statisticians, engineering departments, and computer design specialists here at Stanford and UC Berkeley to extend our efforts to make the program in the laboratory extremely cross-disciplinary.
Dr. Nolan has published over 160 papers, most in top tier journals, has over 18 issued patents, has been cited as one of the top inventors at Stanford, and has a strong record of translating technology and inventions for the public good. Dr. Nolan was recently awarded the Department of Defense Teal Innovator Award for work on ovarian cancer. The journal Nature awarded the Outstanding Research Achievement for 2011 to the Nolan Lab for its work in single-cell analysis by mass cytometry.
Publications
- Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes. Immunity. 2012; (1): 142-52
- From single cells to deep phenotypes in cancer. Nat Biotechnol. 2012; (7): 639-47
- Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators. Nat Biotechnol. 2012; (9): 858-67
- Single-cell mass cytometry adapted to measurements of the cell cycle. Cytometry A. 2012; (7): 552-66
- Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011; (6030): 687-96
- Alternate mechanisms of initial pattern recognition drive differential immune responses to related poxviruses. Cell Host Microbe. 2010; (2): 174-85
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