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Stephen J SmithAcademic Appointments
Appointment
Organization
Professor
Member
Member
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Curriculum Vitae PDF
Postdoctoral Advisees
Estuardo Robles,
Gordon Wang
Web Site Links
Research/Lab website:
Smith Laboratory Site
Research Interests
Research in the Smith Laboratory addresses brain development and function. Special interests include dynamic and structural aspects of synaptogenesis, cell-cell adhesion and synaptic plasticity. The experimental approach uses sophisticated optical imaging techniques to study live neural cells in cultures, tissues and intact organisms. Recent projects have addressed the dynamics of dendrite growth and presynaptic vesicle pools in hippocampus, the effects of patterned electrical activity in developing tissues, and cytoskeletal rearrangements during cell-cell adhesion events.
Publications
- Micheva KD, Smith SJ "Array tomography: a new tool for imaging the molecular architecture and ultrastructure of neural circuits." Neuron 2007; 55: 1: 25-36 More »
- Stevens B, Allen NJ, Vazquez LE, Howell GR, Christopherson KS, Nouri N, Micheva KD, Mehalow AK, Huberman AD, Stafford B, Sher A, Litke AM, Lambris JD, Smith SJ, John SW, Barres BA "The classical complement cascade mediates CNS synapse elimination." Cell 2007; 131: 6: 1164-78 More »
- Smith SJ, "Circuit reconstruction tools today." Curr Opin Neurobiol 2007; More »
- Levi O, Lee TT, Lee MM, Smith SJ, Harris JS "Integrated semiconductor optical sensors for cellular and neural imaging." Appl Opt 2007; 46: 10: 1881-9 More »
- Meyer MP, Smith SJ "Evidence from in vivo imaging that synaptogenesis guides the growth and branching of axonal arbors by two distinct mechanisms." J Neurosci 2006; 26: 13: 3604-14 More »
19 publications: view full list
