{"result":[{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9852&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Brigit_Riley","appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"Brigit","primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","displayName":"Brigit Erin RILEY","lastName":"Riley"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9630&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/James_Olzmann","appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"James","primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","displayName":"James Olzmann","lastName":"Olzmann"},{"researchInterest":"The long term goal  of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether  reengineering chaperone networks can provide therapeutic strategies.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6222&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Judith_Frydman","appointments":[{"appointment":"Associate Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Judith","primaryAppointment":"Associate Professor,Biology (School of Humanities and Sciences)","displayName":"Judith Frydman","lastName":"Frydman"},{"researchInterest":"Ion channels and signal transduction;  patch clamp and fluorometric analysis; cell and molecular biology; cystic fibrosis gene therapy.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4500&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Phyllis_Gardner","appointments":[{"appointment":"Professor,Medicine - Clinical Pharmacology"}],"clinicalFocus":[{"focus":"Clinical Pharmacology"}],"firstName":"Phyllis","primaryAppointment":"Professor,Medicine - Clinical Pharmacology","displayName":"Phyllis Gardner","lastName":"Gardner"},{"researchInterest":"Information transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8533&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Thomas_Sudhof","appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Psychiatry & Behavioral Science"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Professor,Molecular & Cellular Physiology","displayName":"Thomas Sudhof","lastName":"Sudhof"},{"researchInterest":"Our laboratory studies virus-host interactions with an emphasis microRNA-mediated gene regulation and on translational control. The mechanism by which a liver-specific microRNA regulates hepatitis C virus genome replication is under intense scrutiny. In addition, the mechanism of internal ribosome entry in certain cellular and viral mRNAs and its biological role in growth and development is being investigated.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4458&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Peter_Sarnow","appointments":[{"appointment":"Professor,Microbiology & Immunology"}],"clinicalFocus":[],"firstName":"Peter","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"Peter Sarnow","lastName":"Sarnow"},{"researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Garry_Nolan","appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Garry","primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","displayName":"Garry Nolan","lastName":"Nolan"},{"researchInterest":"Our laboratory studies molecular interactions that underlie the establishment and maintenance of cell and tissue structure.  Our specific areas of interest are the targeted delivery of proteins to intracellular membranes, the architecture and dynamics of intercellular adhesion junctions, and signaling pathways that govern cell fate determination.  We also have a long-standing interest in carbohydrate-based cellular recognition and adhesion.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4259&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/William_Weis","appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"William","primaryAppointment":"Professor,Structural Biology","displayName":"William Weis","lastName":"Weis"},{"researchInterest":"The goal of our research is to elucidate the molecular mechanisms by which proteins are targeted to specific membrane compartments. How do transport vesicles select their contents, bud, translocate through the cytoplasm, and then fuse with their targets? We study the Ras-like Rab GTPases--how they are localized to distinct intracellular compartments in human cells, and how they serve as master regulators of all receptor trafficking events.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4087&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Suzanne_Pfeffer","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Suzanne","primaryAppointment":"Professor,Biochemistry","displayName":"Suzanne Pfeffer","lastName":"Pfeffer"},{"researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3890&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Craig_Garner","appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Craig","primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","displayName":"Craig C. Garner","lastName":"Garner"},{"researchInterest":"Three-dimensional structure determination and biophysical studies of macromolecules.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4099&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/David_McKay","appointments":[{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"David","primaryAppointment":"Emeritus Faculty, Acad Council,Structural Biology","displayName":"David B. McKay","lastName":"McKay"},{"researchInterest":"Gene Regulation; Molecular Immunology; Lymphocyte subsets; Fluorescence-Activated Cell\u000bSorter (FACS) development; AIDS; Apoptosis; Redox Regulation; Gene Arrays; and the theraphy of AIDS using the anti-oxidant N'acetylcysteine(NAC).","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4151&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Leonard_Herzenberg","appointments":[{"appointment":"Emeritus (Active) Professor,Genetics"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Leonard","primaryAppointment":"Emeritus (Active) Professor,Genetics","displayName":"Leonard Herzenberg","lastName":"Herzenberg"},{"researchInterest":"B-cell development; Ig rearrangement and repertoire analysis; T cell regulation of antibody\u000bresponses; T cell subsets; glutathione regulation of HIV disease progression; Fluorescence-Activated Cell Sorting (FACS) related software development and gene arrays.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6113&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Leonore_Herzenberg","appointments":[{"appointment":"Professor (Research),Genetics"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Leonore","primaryAppointment":"Professor (Research),Genetics","displayName":"Leonore A. Herzenberg","lastName":"Herzenberg"},{"researchInterest":"Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology.  We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4370&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Chris_Garcia","appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Chris","primaryAppointment":"Professor,Molecular & Cellular Physiology","displayName":"Chris Garcia","lastName":"Garcia"},{"researchInterest":"Molecular mechanisms of chloride channels & transporters studied by integration of structural and electrophysiological methods.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3812&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Merritt_Maduke","appointments":[{"appointment":"Associate Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Merritt","primaryAppointment":"Associate Professor,Molecular & Cellular Physiology","displayName":"Merritt Maduke","lastName":"Maduke"},{"researchInterest":"The biochemistry of RNA-dependent RNA polymerase function, the cell biology of the membrane rearrangements induced by positive-strand RNA virus infection of human cells, and the genetics of RNA viruses, which, with their high error rates, live at the brink of error catastrophe, are investigated in the Kirkegaard laboratory.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4459&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Karla_Kirkegaard","appointments":[{"appointment":"Professor,Microbiology & Immunology"}],"clinicalFocus":[],"firstName":"Karla","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"Karla Kirkegaard","lastName":"Kirkegaard"},{"researchInterest":"Research in Dr. Deisseroth's laboratory focuses on developing optical, molecular and cellular tools to observe, perturb, and re-engineer brain circuits. His laboratory is based in the James H. Clark Center at Stanford and has developed optogenetic and tissue engineering methods, employing techniques spanning electrophysiology, molecular biology, optics, neural activity imaging, animal behavior, and computational neural network modeling.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6080&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Karl_Deisseroth","appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Associate Professor,Bioengineering"},{"appointment":"Associate Professor,Psychiatry & Behavioral Science"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Psychiatry"}],"firstName":"Karl","primaryAppointment":"Assistant Professor,Bioengineering","displayName":"Karl Deisseroth","lastName":"Deisseroth"},{"researchInterest":"Molecular mechanisms of lymphocyte recognition and differentiation; molecular genetics and expression of T-cell receptor genes.  Dynamics and functionality of specific T cell populations in human cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4282&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Mark_Davis","appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Mark","primaryAppointment":"Professor,Microbiology & Immunology","displayName":"Mark M. Davis","lastName":"Davis"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8903&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Marija_Vrljic","appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"clinicalFocus":[],"firstName":"Marija","primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","displayName":"Marija Vrljic","lastName":"Vrljic"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9965&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Peter_Kasson","appointments":[{"appointment":"Postdoctoral Research fellow, Chemistry"}],"clinicalFocus":[],"firstName":"Peter","primaryAppointment":"Postdoctoral Research fellow, Chemistry","displayName":"Peter Kasson","lastName":"Kasson"},{"researchInterest":"The role of chromatin in stem cell formation and function.  Development of small molecule regulators as experimental probes and therapeutic leads.  Signaling through calcineurin  and NFAT in vertebrate development.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4283&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Gerald_Crabtree","appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Gerald","primaryAppointment":"Professor,Pathology","displayName":"Gerald Crabtree","lastName":"Crabtree"},{"researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine.  In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory  focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7126&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Michael_Clarke","appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"firstName":"Michael","primaryAppointment":"Professor,Medicine - Oncology","displayName":"Michael F. Clarke, M.D.","lastName":"Clarke"},{"researchInterest":"Dr. Dodd is involved in clinical trials using endovascular coils that have a fiber coating that help heal aneurysms of the neck and can prevent an aneurysm from reforming. He uses minimally invasive endoscopic techniques to treat brain tumors.\r\n\r\nDodd's research interests are in cerebral blood vessel reactivity and stroke.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6790&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Robert_Dodd","appointments":[{"appointment":"Assistant Professor - Med Center Line,Neurosurgery"},{"appointment":"Assistant Professor - Med Center Line,Radiology"}],"clinicalFocus":[{"focus":"Interventional Neuroradiology"},{"focus":"Neurosurgery"}],"firstName":"Robert","primaryAppointment":"Assistant Professor - Med Center Line,Neurosurgery","displayName":"Robert Dodd","lastName":"Dodd"},{"researchInterest":"Understanding genetic basis of cardiovascular function and disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Thomas_Quertermous","appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","displayName":"Thomas Quertermous, MD","lastName":"Quertermous"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9452&type=small&showNoImage","href":"http://med.stanford.edu/profiles/biophysics/researcher/Ofer_Yizhar","appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"clinicalFocus":[],"firstName":"Ofer","primaryAppointment":"Postdoctoral Research fellow, Bioengineering","displayName":"Ofer Yizhar","lastName":"Yizhar"}]}