Stanford School of Medicine
Biophysics–

Uel Jackson McMahan

Email:
Phone:(650) 723-7489
Profile: http://med.stanford.edu/profiles/Uel_McMahan/
Academic Appointments
Appointment
Organization
Emeritus (Active) Professor
Neurobiology
Emeritus Faculty, Acad Council
Neurobiology
Emeritus Faculty, Acad Council
Structural Biology
Member
Bio-X
Graduate & Fellowship Program Affiliations
Biophysics ; Neurosciences ;
 
Honors & Awards
Title
Organization
Date(s)
Research Career Development Award
NIH
1973-1977
Jacob Javits Neurosciences Investigator Award
NIH
1984-1991
Jacob Javits Neurosciences Investigator Award
NIH
1991-1998
Alumni Achievement Award
Westminster College, Fulton, MO
1996
Prix (Plasticite Neuronale): shared with G. Fischbach (Harvard) and H.Betz (MPI, Frankfurt)
Fondation IPSEN/Fondation de France
1998
Administrative Appointments
Title
Organization
Start Year
End Year
Member
Appointments and Promotions (A&P) Committee, School of Medicine
2005
2008
Member
Administrative Panel for Laboratory Animal Care (APLAC)
1999
2005
Chairman
Committee on Graduate Studies
1989
1990
Chairman
Department of Neurobiology
1987
1992
Director
Neurosciences Program
1986
1991
Professional Education
Degree
Awarding Institution
Field of Study
Year of Graduation
B.A.
Westminster College, Fulton, MO
Biology
1960
Ph.D.
U Tennessee Med Units, Memphis,TN
Anatomy
1964
Postdoctoral Advisees
Joseph Szule
Web Site Links
Research/Lab website:   Uel Jackson McMahan Laboratory
Research Interests

We use three-dimensional reconstructions of tissue sections generated by electron microscope tomography to study the organization and behavior of macromolecules at the nervous system’s synapses. The information we obtain provides insights unobtainable in any other way about the molecular mechanisms involved in synaptic impulse transmission and the sequence of steps in synapse formation. To augment our studies we are developing methods for localizing known proteins to specific macromolecules observed by tomography and for the quantitative analysis of tomographic data, technologies that can be applied to the investigation of macromolecules in any tissue.

Community and International Work
  • Visiting Lecture Team Program, Economically underdeveloped nations More »
Publications
  • D.B. Ress, M.L. Harlow, R.M. Marshall, U.J. McMahan "Methods for generation high-resolution structural models from electron microscope tomography data." Structure 2004; 12: 10: 1763-1774 More »
  • Harlow ML, Ress D, Stoschek A, Marshall RM, McMahan UJ "The architecture of active zone material at the frog's neuromuscular junction." Nature 2001; 409: 6819: 479-84 More »
  • Ress D, Harlow ML, Schwarz M, Marshall RM, McMahan UJ "Automatic acquisition of fiducial markers and alignment of images in tilt series for electron tomography." J Electron Microsc (Tokyo) 1999; 48: 3: 277-87 More »
  • Harlow M, Ress D, Koster A, Marshall RM, Schwarz M, McMahan UJ "Dissection of active zones at the neuromuscular junction by EM tomography." J Physiol Paris 1998; 92: 2: 75-8 More »
  • Rimer M, Cohen I, Lømo T, Burden SJ, McMahan UJ "Neuregulins and erbB receptors at neuromuscular junctions and at agrin-induced postsynaptic-like apparatus in skeletal muscle." Mol Cell Neurosci 1998; 12: 1-2: 1-15 More »
17 publications:   view full list

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