Scientific Focus
Research Interests
Cell cycle control of DNA replication in embryonic and somatic cells: cyclins and the cell cycle in Xenopus embryos.
Publications
- Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors. "Am J Pathol" 2007 ; 5 1793-805
- The END network couples spindle pole assembly to inhibition of the anaphase-promoting complex/cyclosome in early mitosis. "Dev Cell" 2007 ; 1 29-42
- Dual degradation signals control Gli protein stability and tumor formation. "Genes Dev" 2006 ; 3 276-81
- CaMKII and polo-like kinase 1 sequentially phosphorylate the cytostatic factor Emi2/XErp1 to trigger its destruction and meiotic exit. "Proc Natl Acad Sci U S A" 2006 ; 3 608-13
- Climbing the Greatwall to mitosis. "Mol Cell" 2006 ; 2 156-7

