Pehr HarburyAcademic Appointments
Appointment
Organization
Associate Professor
Member
Member
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Postdoctoral Advisees
Casey Krusemark
Research Interests
Our lab engineers proteins and small-molecule drugs at atomic resolution through a combination of structural calculations and combinatorial library synthesis. Our goal is to elucidate predictive principles by which novel shapes and catalytic properties can be conferred accurately on designed polypeptides.
Publications
- Boas FE, Harbury PB "Potential energy functions for protein design." Curr Opin Struct Biol 2007; More »
- Wrenn SJ, Harbury PB "Chemical Evolution as a Tool for Molecular Discovery." Annu Rev Biochem 2006; More »
- Halpin DR, Lee JA, Wrenn SJ, Harbury PB "DNA Display III. Solid-Phase Organic Synthesis on Unprotected DNA." PLoS Biol 2004; 2: 7: E175 More »
- Halpin DR, Harbury PB "DNA Display II. Genetic Manipulation of Combinatorial Chemistry Libraries for Small-Molecule Evolution." PLoS Biol 2004; 2: 7: E174 More »
- Halpin DR, Harbury PB "DNA display I. Sequence-encoded routing of DNA populations." PLoS Biol 2004; 2: 7: E173 More »
13 publications: view full list
