Stanford School of Medicine
Biophysics–

James Ferrell

Email:
Phone:(650) 725-0765
Profile: http://med.stanford.edu/profiles/James_Ferrell/
Academic Appointments
Appointment
Organization
Professor
Chemical and Systems Biology
Professor
Biochemistry
Member
Cancer Center
Graduate & Fellowship Program Affiliations
Biochemistry ; Biophysics ; Cancer Biology ; Chemical and Systems Biology ;
 
Administrative Appointments
Title
Organization
Start Year
End Year
Chair
Stanford University School of Medicine - Chemical & Systems Biology
2006
-
Professional Education
Degree
Awarding Institution
Field of Study
Year of Graduation
B.A.
Williams College
Physics, Chemistry, Mathematics
1976
Ph.D.
Stanford University
Chemistry
1984
M.D.
Stanford University
-
1986
Postdoctoral Advisees
Sun Kim, Silvia Magalhaes Dos Santos
Web Site Links
Research/Lab website:   http://www.stanford.edu/group/ferrelllab/
Research Interests

Our research centers on the signal transduction circuits that trigger the entry into mitotic and meoitic M-phase, the progression through these phases, and the exit from M-phase to interphase.

Some of our work is aimed at identifying as-yet unidentified components of these regulatory circuits. The rest of our work is aimed at understanding the systems level logic of these circuits--how cells build reliable switches, oscillators, and response networks out of imperfect components.

Community and International Work
  • PRD-1-Day Band Performance, Opening Ceremony, Guangzhou Triennial, Guangzhou, China More »
Publications
  • Ferrell JE, "Feedback regulation of opposing enzymes generates robust, all-or-none bistable responses." Curr Biol 2008; 18: 6: R244-5 More »
  • Hendrickson DG, Hogan DJ, Herschlag D, Ferrell JE, Brown PO "Systematic Identification of mRNAs Recruited to Argonaute 2 by Specific microRNAs and Corresponding Changes in Transcript Abundance." PLoS ONE 2008; 3: 5: e2126 More »
  • Tsai TY, Choi YS, Ma W, Pomerening JR, Tang C, Ferrell JE "Robust, Tunable Biological Oscillations from Interlinked Positive and Negative Feedback Loops." Science 2008; 321: 5885: 126-129 More »
  • Pomerening JR, Ubersax JA, Ferrell JE "Rapid Cycling and Precocious Termination of G1 Phase in Cells Expressing CDK1AF." Mol Biol Cell 2008; More »
  • Gong D, Pomerening JR, Myers JW, Gustavsson C, Jones JT, Hahn AT, Meyer T, Ferrell JE "Cyclin A2 regulates nuclear-envelope breakdown and the nuclear accumulation of cyclin b1." Curr Biol 2007; 17: 1: 85-91 More »
82 publications:   view full list

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