William Greenleaf
Key Documents
Contact Information
- Academic Offices
Personal Information Email Tel (650) 725-3672
Professional Overview
Honors and Awards
- Damon Runyon Cancer Research Fellowship, Damon Runyon Foundation (2009-2011)
- ARCS Fellowship, ARCS (2006)
- Gates Cambridge Trust Scholar, Gates Foundation (2002-2003)
- Graduate Fellowship, National Science Foundation (2003-2005)
Professional Education
| Postdoctoral Fellow: | Harvard University, Chemistry and Chemical Biology |
| PhD: | Stanford University, Applied Physics (2008) |
| Dip Comp Sci: | Trinity College, Cambridge University, UK, Computer Science (2003) |
| AB: | Harvard University, Physics (2002) |
Graduate & Fellowship Program Affiliations
Internet Links
Scientific Focus
Current Research Interests
Our lab focuses on developing methods to probe the genome and epigenome at the single-cell and single-molecule levels. Our efforts are split between building new tools to leverage the power of high-throughput sequencing and cutting-edge microscopies, and bringing these new technologies to bear against basic biological questions of genomic and epigenomic variation.
Publications
- Fluorogenic DNA sequencing in PDMS microreactors. Nat Methods. 2011; (7): 575-80
- An optical apparatus for rotation and trapping. Methods Enzymol. 2010: 377-404
- Applied force reveals mechanistic and energetic details of transcription termination. Cell. 2008; (6): 971-82
- Direct observation of hierarchical folding in single riboswitch aptamers. Science. 2008; (5863): 630-3
- Single-molecule studies of RNA polymerase: motoring along. Annu Rev Biochem. 2008: 149-76
- High-resolution, single-molecule measurements of biomolecular motion. Annu Rev Biophys Biomol Struct. 2007: 171-90
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