Markus Covert

Publications

• A noisy paracrine signal determines the cellular NF-kappaB response to lipopolysaccharide. Lee TK, Denny EM, Sanghvi JC, Gaston JE, Maynard ND, Hughey JJ, Covert MW. Sci Signal. 2009; 2 (93): ra65
• Integrating metabolic, transcriptional regulatory and signal transduction models in Escherichia coli. Covert MW, Xiao N, Chen TJ, Karr JR. Bioinformatics. 2008; 24 (18): 2044-50
• Achieving stability of lipopolysaccharide-induced NF-kappaB activation. Covert MW, Leung TH, Gaston JE, Baltimore D. Science. 2005; 309 (5742): 1854-7
• Integrated regulatory and metabolic models Covert, M.W., Computational Systems Biology, Academic Press, New York. 2005
• Reconstruction of microbial transcriptional regulatory networks. Herrgård MJ, Covert MW, Palsson BØ. Curr Opin Biotechnol. 2004; 15 (1): 70-7
• Integrating high-throughput and computational data elucidates bacterial networks. Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO. Nature. 2004; 429 (6987): 92-6
• Constraints-based models: regulation of gene expression reduces the steady-state solution space. Covert MW, Palsson BO. J Theor Biol. 2003; 221 (3): 309-25
• Identifying constraints that govern cell behavior: a key to converting conceptual to computational models in biology? Covert MW, Famili I, Palsson BO. Biotechnol Bioeng. 2003; 84 (7): 763-72
• Reconciling gene expression data with known genome-scale regulatory network structures. Herrgård MJ, Covert MW, Palsson BØ. Genome Res. 2003; 13 (11): 2423-34
• Transcriptional regulation in constraints-based metabolic models of Escherichia coli. Covert MW, Palsson BØ. J Biol Chem. 2002; 277 (31): 28058-64
• Genome-scale metabolic model of Helicobacter pylori 26695. Schilling CH, Covert MW, Famili I, Church GM, Edwards JS, Palsson BO. J Bacteriol. 2002; 184 (16): 4582-93
• Regulation of gene expression in flux balance models of metabolism. Covert MW, Schilling CH, Palsson B. J Theor Biol. 2001; 213 (1): 73-88
• Metabolic modeling of microbial strains in silico. Covert MW, Schilling CH, Famili I, Edwards JS, Goryanin II, Selkov E, Palsson BO. Trends Biochem Sci. 2001; 26 (3): 179-86