Sanjiv Sam Gambhir, MD, PhD
Assessing the suitability of an imaging probe for use in clinical cell and gene therapy trials in cancer and rheumatoid arthritis
Contact Information
Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305Brief
The purpose of this study is to determine whether [18F]FHBG is suitable for use as an imaging probe in cancer or rheumatoid arthritis patients enrolled in cell or gene therapy trials. In this phase 1 study we will assess the safety and biodistribution of [18F]FHBG in patients.
Recruiting Status:
No longer recruitingStanford Recruiting Status:
No longer recruitingIntervention(s):
- Procedure: [18F]FHBG
Phase:
Phase 2Eligibility
Ages Eligible for Study:
18 years to Any AgeGenders Eligible for Study:
Male and FemaleHealth of Volunteers:
People with the conditions listed in this trial can participate as controls.Key Inclusion Criteria:
- Clinical diagnosis of brain tumor or rheumatoid arthritis
Key Exclusion Criteria:
- Below 18 years of age
Additional Study Details
Official Title:
Imaging the Biodistribution of the Positron Emission Tomography Reporter Probe, [18F]FHBG, in Humans.Anticipated start date:
4/19/2005Lead Sponsor:
Stanford UniversityInvestigator(s):
- Sanjiv Sam Gambhir M.D., Ph.D.
- Michael L Goris
- Dr Andrew Quon
- Dr Lawrence Recht
- Shahriar Shah Yaghoubi
Study Type:
InterventionalPurpose:
DiagnosticAllocation:
Non-randomizedMasking:
OpenControl:
Assignment:
Single GroupEndpoints:
N/APrimary Outcomes:
- The primary endpoint of the study for each patient is acquisition of PET/CT image.
Secondary Outcomes:
- Collection of vital signs, EKG, blood chemistry and CBC data
Total Number to be Enrolled:
10Total Number to be Enrolled at Stanford:
10More Information
Publications About this Study:
- 11483684: Yaghoubi S, Barrio JR, Dahlbom M, Iyer M, Namavari M, Satyamurthy N, Goldman R, Herschman HR, Phelps ME, Gambhir SS. Human pharmacokinetic and dosimetry studies of [(18)F]FHBG: a reporter probe for imaging herpes simplex virus type-1 thymidine kinase reporter gene expression. J Nucl Med. 2001 Aug;42(8):1225-34.
Secondary ID(s):
- 95908
- BRNCNS0003
- NCT00185848
Locations & Contacts
Stanford Locations & Contacts:
Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305Non-Stanford Locations:
The Stanford website does not have any locations outside of Stanford listed for this trial. You may want to check clinicaltrials.gov for posible additional locations.
This listing was last updated:
11/5/2009PLEASE NOTE:
Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician. If you do not have a primary care physician please feel free to call the SHC Physician Referral Service at (800) 756-9000 or send an email.
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