Bioengineering

Markus Covert

Email:
Profile: http://med.stanford.edu/profiles/Markus_Covert/
Academic Appointments
Appointment
Organization
Assistant Professor
Bioengineering
Assistant Professor (By courtesy)
Chemical and Systems Biology
Member
Bio-X
Graduate & Fellowship Program Affiliations
Bioengineering ;
 
Honors & Awards
Title
Organization
Date(s)
Robert Black Postdoctoral Fellow
Damon Runyon Cancer Research Foundation
2004-2006
First Graduate of the Bioinformatics Program
University of California, San Diego
2003
Ezra Taft Benson Presidential Scholar
Brigham Young University
1991-1997
Professional Education
Degree
Awarding Institution
Field of Study
Year of Graduation
Ph.D.
UCSD
Bioengineering/ Bioinformatics
2003
M.S.
UCSD
Bioengineering
2002
B.S.
Brigham Young University
Chemical Engineering
1997
Postdoctoral Advisees
Nathaniel Maynard
Web Site Links
Research/Lab website:   Lab Website
Research Interests

Our focus is on building computational models of complex biological processes, and using these models to guide an experimental program. Such an approach leads to a relatively rapid identification and validation of previously unknown components and interactions. Biological systems of interest include metabolic, regulatory and signaling networks as well as cell-cell interactions. Current research involves the dynamic behavior of NF-kappaB, an important family of transcription factors whose aberrant activity has been linked to oncogenesis, tumor progression, and resistance to chemotherapy.

Publications
  • Covert MW, Leung TH, Gaston JE, Baltimore D "Achieving stability of lipopolysaccharide-induced NF-kappaB activation." Science 2005; 309: 5742: 1854-7 More »
  • Covert, M.W., "Integrated regulatory and metabolic models" Computational Systems Biology, Academic Press, New York 2005; More »
  • Covert MW, Knight EM, Reed JL, Herrgard MJ, Palsson BO "Integrating high-throughput and computational data elucidates bacterial networks." Nature 2004; 429: 6987: 92-6 More »
  • Herrgård MJ, Covert MW, Palsson BØ "Reconstruction of microbial transcriptional regulatory networks." Curr Opin Biotechnol 2004; 15: 1: 70-7 More »
  • Covert MW, Famili I, Palsson BO "Identifying constraints that govern cell behavior: a key to converting conceptual to computational models in biology?" Biotechnol Bioeng 2003; 84: 7: 763-72 More »
11 publications:   view full list

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