{"result":[{"lastName":"Li","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=21238&type=small&showNoImage","displayName":"Caiyun Li","firstName":"Caiyun","href":"http://med.stanford.edu/profiles/Caiyun_Li","researchInterest":""},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Sunwoo","clinicalFocus":[{"focus":"Thyroid Neoplasms"},{"focus":"Melanoma"},{"focus":"Parathyroid Neoplasms"},{"focus":"Tongue Neoplasms"},{"focus":"Otolaryngology - Head & Neck Surgery (Ear, Nose and Throat)"},{"focus":"Otolaryngology"},{"focus":"Thyroid Nodule"},{"focus":"Parotid Neoplasms"},{"focus":"Tonsillar Neoplasms"},{"focus":"Pharynx Neoplasms"},{"focus":"Cancer of the Pharynx"},{"focus":"Cancer of the Larynx"},{"focus":"Cancer Stem Cells"},{"focus":"Cancer of Mouth"},{"focus":"Cancer of Neck"},{"focus":"Cancer of the Nasopharynx"},{"focus":"Cancer of Oropharnyx"},{"focus":"Cancer of the Parotid"},{"focus":"Cancer of the Salivary Gland"}],"appointments":[{"appointment":"Assistant Professor,Otolaryngology (Head and Neck Surgery)"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor,Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8588&type=small&showNoImage","displayName":"John B. Sunwoo","firstName":"John","href":"http://med.stanford.edu/profiles/John_Sunwoo","researchInterest":"My laboratory is focused on two primary areas of research: (1) the immune response to head and neck cancer and to a tumorigenic population of cells within these malignancies called cancer stem cells; (2) the developmental programs of a special lymphocyte population involved in innate immunity called natural killer (NK) cells."},{"lastName":"Nguyen","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stanford Cancer Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Stanford Cancer Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24227&type=small&showNoImage","displayName":"Le Xuan Truong Nguyen","firstName":"Le Xuan Truong","href":"http://med.stanford.edu/profiles/Le Xuan Truong_Nguyen","researchInterest":""},{"lastName":"Vinayak","clinicalFocus":[{"focus":"Oncology"},{"focus":"Triple-negative breast cancer"},{"focus":"BRCA-associated breast cancer"},{"focus":"Locally advanced breast cancer"}],"appointments":[{"appointment":"Instructor,Medicine - Oncology"}],"primaryAppointment":"Instructor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10883&type=small&showNoImage","displayName":"Shaveta Vinayak","firstName":"Shaveta","href":"http://med.stanford.edu/profiles/Shaveta_Vinayak","researchInterest":"My research focuses on studying triple-negative breast cancer biology and identifying targeted treatment strategies.  I am interested in designing breast cancer clinical trials with strong translational endpoints so that we can identify a subset of patients who benefit the most from the targeted treatment.  Other interests include, prevention strategies for hormone receptor-negative breast cancer and survivorship issues."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Huang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23069&type=small&showNoImage","displayName":"Shenglin Huang","firstName":"Shenglin","href":"http://med.stanford.edu/profiles/Shenglin_Huang","researchInterest":""},{"lastName":"O'Brien","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Assistant Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35098&type=small&showNoImage","displayName":"Lucy Erin O'Brien","firstName":"Lucy","href":"http://med.stanford.edu/profiles/Lucy_O'Brien","researchInterest":"Many adult organs tune their functional capacity to variable levels of physiologic demand.  Adaptive organ resizing breaks the allometry of the body plan that was established during development, suggesting that it occurs through different mechanisms.  Emerging evidence points to stem cells as key players in these mechanisms.  We use the Drosophila midgut, a stem-cell based organ analogous to the vertebrate small intestine, as a simple model to uncover the rules that govern adaptive remodeling."},{"lastName":"Kaplan","clinicalFocus":[{"focus":"Head and Neck Cancers"},{"focus":"Head and Neck Cancers - Head and Neck Surgery"},{"focus":"Skull Base Tumors "},{"focus":"Salivary Gland Tumors"},{"focus":"Esophageal Cancer"},{"focus":"Esophageal Cancer - Head and Neck Surgery"},{"focus":"Melanoma"},{"focus":"Melanoma - Head and Neck Surgery"},{"focus":"Otolaryngology"},{"focus":"Otolaryngology - Head & Neck Surgery (Ear, Nose and Throat)"},{"focus":"Salivary Gland Tumors - Head and Neck Surgery"},{"focus":"Skull Base Tumors - Head and Neck Surgery"},{"focus":"Thyroid Neoplasms"},{"focus":"squamous cell carcinoma of the head and neck"},{"focus":"Paranasal Sinus Neoplasms"},{"focus":"Esthesioneuroblastoma, Paranasal Sinus-Nasal Cavity"},{"focus":"carcinoma of the neck; unknown primary"},{"focus":"Parotid Neoplasms"},{"focus":"Tongue Neoplasms"},{"focus":"Oral cavity tumors"},{"focus":"Maxillary Sinus Neoplasms"},{"focus":"Paraganglioma, Carotid Body"},{"focus":"Parapharyngeal space tumors"},{"focus":"Infratemporal fossa tumors"},{"focus":"Tonsillar Neoplasms"}],"appointments":[{"appointment":"Professor - Med Center Line,Otolaryngology (Head and Neck Surgery)"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor - Med Center Line (By courtesy),Neurosurgery"}],"primaryAppointment":"Professor - Med Center Line,Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3950&type=small&showNoImage","displayName":"Michael J. Kaplan","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Kaplan","researchInterest":"1) New therapeutic approaches for head and neck cancer, including immune stimulation possibilities (IRX-2 protocol), integration of biological modifiers, and, eventually, genetic approaches.\r\n2) Head and neck cancer stem cells: identification,  characterization, control--in conjunction with the Irv Weissman and Michael Clarke labs in the Stem Cell Institute \r\n3) Development of innovative surgical methods at the anterior cranial base"},{"lastName":"Sarin","clinicalFocus":[{"focus":"Dermatology"},{"focus":"Precision Dermatology"},{"focus":"Skin Cancers"},{"focus":"Adverse Drug Reactions"}],"appointments":[{"appointment":"Clinical Assistant Professor,Dermatology"}],"primaryAppointment":"Clinical Assistant Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=33859&type=small&showNoImage","displayName":"Kavita Sarin","firstName":"Kavita","href":"http://med.stanford.edu/profiles/Kavita_Sarin","researchInterest":""},{"lastName":"Chu","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Dean's Office"},{"appointment":"Student Resident Asst,Academic and Residential Computing - Student Computing"}],"primaryAppointment":"Ph.D., Dean's Office","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19664&type=small&showNoImage","displayName":"Ci Chu","firstName":"Ci","href":"http://med.stanford.edu/profiles/Ci_Chu","researchInterest":"lncRNA and regulation of gene expression."},{"lastName":"Rosen","clinicalFocus":[{"focus":"Pulmonology (Lung) and Critical Care "},{"focus":"Pulmonary Disease"}],"appointments":[{"appointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4245&type=small&showNoImage","displayName":"Glenn Rosen","firstName":"Glenn","href":"http://med.stanford.edu/profiles/Glenn_Rosen","researchInterest":"Our laboratory examines apoptotic and cell cycle pathways in cancer and lung disease. We have identified a novel cell cycle protein which regulates cell cycle progression in immune cells and the lung.  We are also studying signaling pathways that regulate cancer cell growth and metastasis."},{"lastName":"Pinto","clinicalFocus":[{"focus":"Medical Oncology"},{"focus":"Head and Neck Cancer"},{"focus":"Oncology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Oncology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Associate Professor - Med Center Line (By courtesy),Otolaryngology (Head and Neck Surgery)"}],"primaryAppointment":"Associate Professor - Med Center Line,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4027&type=small&showNoImage","displayName":"Harlan Pinto","firstName":"Harlan","href":"http://med.stanford.edu/profiles/Harlan_Pinto","researchInterest":"Clinical Interests: general oncology, head and neck cancer Research Interests: chemoprevention trials and combined modality approaches to head and neck cancer"},{"lastName":"Lowndes","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Dean's Office"}],"primaryAppointment":"Ph.D., Dean's Office","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20027&type=small&showNoImage","displayName":"Molly Lowndes","firstName":"Molly","href":"http://med.stanford.edu/profiles/Molly_Lowndes","researchInterest":""},{"lastName":"Artandi","clinicalFocus":[{"focus":"Internal Medicine"},{"focus":"General Internal Medicine"}],"appointments":[{"appointment":"Clinical Assistant Professor,Medicine - General Medical Disciplines"}],"primaryAppointment":"Clinical Assistant Professor,Medicine - General Medical Disciplines","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6449&type=small&showNoImage","displayName":"Maja Artandi, MD","firstName":"Maja","href":"http://med.stanford.edu/profiles/Maja_Artandi","researchInterest":""},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7143&type=small&showNoImage","displayName":"Albert J. Wong, M.D.","firstName":"Albert","href":"http://med.stanford.edu/profiles/Albert_Wong","researchInterest":"Our goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring  mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective."}]}