 |
|
|
Terrence BlaschkeAcademic Appointments
Appointment
Organization
Emeritus Faculty, Acad Council
|
Curriculum Vitae PDF
NIH Biosketch DocHonors & Awards
Title
Organization
Date(s)
Oscar B. Hunter Award
American Society for Clinical Pharmacology and Therapeutics (ASCPT)
2007
Henry W. Elliott Distinguished Service Award
American Society for Clinical Pharmacology and Therapeutics (ASCPT)
2006
Honorary Fellowship
American College of Clinical Pharmacology
2004
Rawls-Palmer Progress in Medicine Lecture and Award
American Society for Clinical Pharmacology and Therapeutics
2002
Henry J. Kaiser Award for Outstanding Contributions to Medical Education
Stanford University School of Medicine
1999
Administrative Appointments
Title
Organization
Start Year
End Year
Assistant Dean for Medical Student Advising
Stanford University School of Medicine
2006
-
Associate Dean for Medical Student Advising
Stanford University School of Medicine
2002
2006
Professional Education
Degree
Awarding Institution
Field of Study
Year of Graduation
B.S.
University of Denver
Honors Program, Mathematics
1964
M.D.
Columbia University, P&S
Medicine
1968
Research Interests
My ongoing Stanford research activities involve studies on the clinical pharmacology of drugs used in HIV-infected patients.
A focus of my laboratory’s efforts in investigating drugs used in HIV-infected patients is to optimize the individual benefit/risk of pharmacotherapy of HIV or opportunistic infections by discovering and quantifying the pharmacokinetics and pharmacodynamics (PK/PD) of drugs used in such therapy; i.e., the distribution of individual-specific dose-concentration-effect relationships in the population. My laboratory has a special interest in understanding the relationships between antiviral drug exposure and virologic and toxicological responses. In the past this has lead to studies examining drug-taking behavior in these patients, since exposure is a function of both individual variability in pharmacokinetics and individual patterns of drug-taking behavior.
At the present time, my interests in HIV are in the access and quality of antiretroviral drugs for patients from less developed countries. The use of substandard drugs carries a high risk of promoting drug resistant variants of HIV, which could have widespread consequences over the long term. Another interest is drug-drug interactions between antiretroviral drugs and drugs used to treat opportunistic infections, in particular drugs used to treat tuberculosis.
Community and International Work
- AMPATH Program, Eldoret, Kenya More »
Publications
- Abiose AK, Aronow WS, Moreno H, Nair CK, Blaschke TF, Hoffman BB "Increased Vascular alpha1-Adrenergic Sensitivity in Patients With Renal Failure: Receiving Recombinant Erythropoeitin." Am J Ther 2007 September/October; 14: 5: 427-434 More »
- Kshirsagar SA, Blaschke TF, Sheiner LB, Krygowski M, Acosta EP, Verotta D "Improving Data Reliability Using a Non-Compliance Detection Method versus Using Pharmacokinetic Criteria." J Pharmacokinet Pharmacodyn 2006; More »
- Motoya T, Thevanayagam LN, Blaschke TF, Au S, Stone JA, Jayewardene AL, Chi J, Aweeka FT "Characterization of nelfinavir binding to plasma proteins and the lack of drug displacement interactions." HIV Med 2006; 7: 2: 122-8 More »
- Osterberg L, Blaschke T "Adherence to medication." N Engl J Med 2005; 353: 5: 487-97 More »
- Washington CB, Flexner C, Sheiner LB, Rosenkranz SL, Segal Y, Aberg JA, Blaschke TF "Effect of simultaneous versus staggered dosing on pharmacokinetic interactions of protease inhibitors." Clin Pharmacol Ther 2003; 73: 5: 406-16 More »
86 publications: view full list
