Sylvia K. Plevritis, PhD
Academic Appointments
- Associate Professor (Research), Radiology - Diagnostic Radiology
- Member, Bio-X
- Member, Cancer Center
Contact Information
-
Academic Offices
Personal Information Email Tel (650) 498-5261
Scientific Focus
Research Interests
My research program focuses on computational modeling of cancer biology and cancer outcomes. We develop stochastic models of the natural history of cancer based on clinical research data. We estimate population-level outcomes under differing screening and treatment interventions. We also analyze genomic and proteomic cancer data in order to identify molecular networks that are perturbed in cancer initiation and progression and relate these perturbations to patient outcomes.
Publications
- Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev. 2009; (20): 2376-81
- Modeling the transition of lung cancer from early to advanced stage. Cancer Causes Control. 2009; (9): 1559-69
- Simultaneous class discovery and classification of microarray data using spectral analysis. J Comput Biol. 2009; (7): 935-44
- Fast calculation of pairwise mutual information for gene regulatory network reconstruction. Comput Methods Programs Biomed. 2009; (2): 177-80
- A pluripotency signature predicts histologic transformation and influences survival in follicular lymphoma patients. Blood. 2009; (15): 3158-66
Help