Shawn L. Chavez
Academic Appointments
- Postdoctoral Research fellow, Cancer/Stem Cell Biology Institute
Professional Snapshot
Honors and Awards
- Dean's Honor List, University of California, Santa Barbara (1994-1997)
- Howard Hughes Medical Institute (HHMI) Undergraduate Fellowship, University of California, Santa Barbara (1996)
- Distinction in Major Award, University of California, Santa Barbara (1997)
- Honors at Graduation, University of California, Santa Barbara (1997)
- Dr. John Gusdon Memorial New Investigator Award, American Society for Reproductive Immunology (ASRI) (2001)
Professional Education
| Doctor of Philosophy: | Yale University, (2006) |
| M.S./M.Phil.: | Yale University, Molecular, Cellular & Developmental Bio (2003) |
| B.S.: | University of CA, Santa Barbara, Biological Sciences (1997) |
Faculty Advisor
Web Site Links
Scientific Focus
Research Interests
My current work is focused on the role of DNA Methyltransferases (DNMTs) in human germ cell differentiation and imprinting. Previous studies in rodents suggest that DNA methylation may contribute to the regulation of germ cell differentiation. Therefore, we are evaluating the expression and function of DNMTs in hESC-derived germ cells throughout development and determining their importance for normal germ cell differentiation and imprinting.
Publications
- Isolation and characterization of pluripotent human spermatogonial stem cell-derived cells. Stem Cells. 2009; (1): 138-49
- AKT Controls Human First Trimester Trophoblast Cell Sensitivity to FAS-Mediated Apoptosis by Regulating XIAP Expression. Biol Reprod. 2009
- The isolation and characterization of a novel telomerase immortalized first trimester trophoblast cell line, Swan 71. Placenta. 2009; (11): 939-48
- Instructing an embryonic stem cell-derived oocyte fate: lessons from endogenous oogenesis. Endocr Rev. 2009; (3): 264-83
- Characterization of six new human embryonic stem cell lines (HSF7, -8, -9, -10, -12, and -13) derived under minimal-animal component conditions. Stem Cells Dev. 2008; (3): 535-46
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