Sanjiv Sam Gambhir, MD, PhD

Clinical Focus

• Nuclear Medicine
• Radiology
• PET Scan

Administrative Appointments

• Director, Canary Center for Cancer Early Detection at Stanford (2009 - present)
• Professor, Bioengineering (2005 - present)
• Director, Molecular Imaging Program at Stanford (MIPS) (2003 - present)
• Head, Division of Nuclear Medicine (2003 - present)
• Professor, Department of Radiology and Bio-X Program (2003 - present)

Honors and Awards

• Outstanding Researcher Award, Radiological Society of Northern California (2009)
• Parmley Prize, American College of Cardiology Foundations (2009)
• Stanford University Endowed Professorship, Virginia and D. K. Ludwig Professor for Clinical Investigation in Cancer Research (2009)
• IOM member, Institute of Medicine of the National Academies. (2008)
• Tesla Medal, UK Royal College of Radiologists (2008)

Professional Education

Postdoctoral Advisees

Benjamin Cosgrove , Anca Dragulescu-Andrasi , Hua Fan-Minogue , Eric Gonzalez , Ben Hackel , Aileen Hoehne , Sharon Hori , Mei Huang , Nicholas Hughes , Ken Ito , Michelle James , Jesse Jokerst , Sri Rajasekhar Kothapalli , Natesh Parashurama , Jennifer Prescher , John Ronald , Arghavan Salles , Bin Shen , Abhinav Singh , Bryan Smith , Cristina Zavaleta , Keren Ziv

Web Site Links

• Molecular Imaging Program at Stanford

Industry Relationships

Stanford is committed to ethical and transparent interactions with our industry partners. It is our policy to disclose payments of $5,000 or more, equity valued at $5,000 or more in a publicly traded company, or any equity in a privately held company, to physicians and scientists employed by Stanford University from companies or other commercial entities with which they interact as part of their professional activities. View Full Information

Current Research Interests

My laboratory focuses on merging advances in molecular biology with those in biomedical imaging to advance the new field of molecular imaging. Methods to image gene expression in living subjects have been developed. Newer approaches to image fundamental cellular events with optical and radiolabeled probes are under active investigation. These imaging approaches are expected to have a fundamental impact in the study of cancer biology, as well as in molecular therapeutics including gene therapy

Clinical Trials

• 18 F-fluoride PET/CT versus 99Tc-MDP Scanning for Detecting Bone Metastases Recruiting
• Assessing the suitability of an imaging probe for use in clinical cell and gene therapy trials in cancer and rheumatoid arthritis Recruiting
• Combined F18 and F18 FDG PET/CT for Evaluation of Malignancy Recruiting
• PET/CT and Whole-Body MRI for Detection of Skeletal and Soft Tissue Metastases Recruiting
• Adjunctive Efficacy Study Of The SoftScan® Optical Breast Imaging System Recruiting

Publications

• A red-shifted Renilla luciferase for transient reporter-gene expression. Loening AM, Dragulescu-Andrasi A, Gambhir SS. Nat Methods. 2010; 7 (1): 5-6
• Molecular imaging of phosphorylation events for drug development. Chan CT, Paulmurugan R, Reeves RE, Solow-Cordero D, Gambhir SS. Mol Imaging Biol. 2009 May-Jun; 11 (3): 144-58
• Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation. Chen IY, Greve JM, Gheysens O, Willmann JK, Rodriguez-Porcel M, Chu P, Sheikh AY, Faranesh AZ, Paulmurugan R, Yang PC, Wu JC, Gambhir SS. Mol Imaging Biol. 2009 May-Jun; 11 (3): 178-87
• Simulations of virtual PET/CT 3-D bronchoscopy imaging using a physical porcine lung-heart phantom. Yerushalmi D, Mullick R, Quon A, Fahrig R, Pelc NJ, Fann JI, Gambhir SS. Mol Imaging Biol. 2009 Jul-Aug; 11 (4): 275-82
• Combined 18F-FDG and Fluoride Approach in PET/CT Imaging: Is There a Clinical Future? Iagaru A, Mittra E, Goris ML, Gambhir SS. J Nucl Med. 2009