Russ B. Altman

Email:
Phone:(650) 725-0659
Profile: http://med.stanford.edu/profiles/Russ_Altman/

Alternate Contact:
Name: Tiffany Murray
Title: Administrative Associate
Email: tiffany.murray@stanford.edu
Phone: 650-725-0659

Academic Appointments
Appointment
Organization
Professor
Professor
Professor (By courtesy)
Computer Science
Professor
Member
Member
Graduate & Fellowship Program Affiliations
 
Honors & Awards
Title
Organization
Date(s)
Fellow
American Institute for Medical and Biological Engineering
2007
Fellow
American College of Physicians
1998
U.S. Presidential Early Career Award for Scientists & Engineers
NIH
1997
Post-Doctoral Fellowship
Howard Hughes Medical Institute
1991
Award for Excellence in Graduate Teaching
Stanford Medical School
2000
6  honors and awards: view full list
Administrative Appointments
Title
Organization
Start Year
End Year
Chairman
Department of Bioengineering
2007
-
Director
Biomedical Informatics Training Program
2000
-
Member
Biomedical Library and Informatics Research Commitee Study Section (NIH)
2002
2005
President
International Society for Computational Biology
2000
2001
Professional Education
Degree
Awarding Institution
Field of Study
Year of Graduation
AB
Harvard College
Biochemistry & Molecular Biology
1983
PhD
Stanford University
Medical Information Sciences
1989
MD
Stanford University
Medicine
1990
Web Site Links
Research/Lab website:   Home Page
Research Interests

I am interested in the application of computational technologies to problems in molecular biology of relevance to medicine. In particular, my laboratory focuses on three areas. First, we are interested in building structured information repositories to support biological research. Our first effort was the RiboWEB resource for supporting studies of the bacterial ribosome (http://riboweb.stanford.edu). Our latest effort is in the creation of a comprehensive pharmacogenomics knowledge base (http://www.pharmgkb.org/) that provides access to information relating genotype to phenotype (in particular, how variation in genetics leads to variation in response to drugs). Second, we are interested in the elucidation and analysis of three dimensional structures. We have projects for computing 3D molecular structures from sparse and noisy data, and for analyzing these structures to recognize and annotate active sites. We are interested in physics-based simulation of biological structures (http://simbios.stanford.edu/). Third, we are interested in computational methods for analyzing functional genomics information. We are focusing on the use of natural language processing techniques for extracting and summarizing information, and in the development of novel methods for analyzing microarray expression data. We are applying these technologies to the study of functional genomics.

Community and International Work
  • Attending Physician, Medicine, Menlo Park, CA More »
Publications
  • Laederach A, Chan JM, Schwartzman A, Willgohs E, Altman RB "Coplanar and coaxial orientations of RNA bases and helices." RNA 2007; More »
  • Altman RB, "PharmGKB: a logical home for knowledge relating genotype to drug response phenotype." Nat Genet 2007; 39: 4: 426 More »
  • Owen RP, Klein TE, Altman RB "The Education Potential of the Pharmacogenetics and Pharmacogenomics Knowledge Base (PharmGKB)." Clin Pharmacol Ther 2007; More »
  • Tang S, Liao JC, Dunn AR, Altman RB, Spudich JA, Schmidt JP "Predicting Allosteric Communication in Myosin via a Pathway of Conserved Residues." J Mol Biol 2007; More »
  • Dugan JM, Altman RB "Using surface envelopes to constrain molecular modeling." Protein Sci 2007; 16: 7: 1266-73 More »
126 publications:   view full list