Patricia Bonnavion
Academic Appointments
- Postdoctoral Research fellow, Psychiatry & Behavioral Science
Key Documents
Contact Information
- Academic Offices
Personal Information Email Tel (650) 736-4389
Professional Overview
Stanford Advisors
| Luis de Lecea: | Postdoctoral Faculty Sponsor |
Scientific Focus
Current Research Interests
I earned my Ph.D. in physiology and physiopathology in 2008 at the University Pierre & Marie Curie (UPMC) in Paris. My research interests were initially oriented on the brainstem neural circuits governing sleep/wake transitions with a particular focus on the serotonin (5-HT) signaling. As I joined Luis de Lecea's lab as a postdoc fellow, I pursued studying the dynamic of arousal systems across vigilance states and in response to environmental & behavioral challenges that threaten and disrupt homeostasis. My work focuses on the signal integration and high inter-connectivity of the lateral hypothalamus and monoaminergic neurons using combinations of optogenetics, behavior and EEG analysis.
Publications
- Mechanism for Hypocretin-mediated sleep-to-wake transitions. Proc Natl Acad Sci U S A. 2012; (39): E2635-44
- [Sleep and wakefulness regulation: molecular players]. Bull Acad Natl Med. 2011; (7): 1551-65; discussion 1565
- Heterogeneous distribution of the serotonin 5-HT(1A) receptor mRNA in chemically identified neurons of the mouse rostral brainstem: Implications for the role of serotonin in the regulation of wakefulness and REM sleep. J Comp Neurol. 2010; (14): 2744-70
- Hypocretins in the control of sleep and wakefulness. Curr Neurol Neurosci Rep. 2010; (3): 174-9
- Neuropeptide S facilitates cue-induced relapse to cocaine seeking through activation of the hypothalamic hypocretin system. Proc Natl Acad Sci U S A. 2010; (45): 19567-72
- Gender-dependent regulation of G-protein-gated inwardly rectifying potassium current in dorsal raphe neurons in knock-out mice devoid of the 5-hydroxytryptamine transporter. J Neurobiol. 2006; (13): 1475-88
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