Stanford School of Medicine
Community Academic Profiles–

Or Gozani

Email:
Profile: http://med.stanford.edu/profiles/Or_Gozani/

Alternate Contact:
Name: Shalien Izzi
Title: Administrative Associate
Email: sizzi@stanford.edu
Phone: 650-724-1512

Academic Appointments
Appointment
Organization
Assistant Professor
Biology (School of Humanities and Sciences)
Member
Cancer Center
Graduate & Fellowship Program Affiliations
Cancer Biology ;
 
Honors & Awards
Title
Organization
Date(s)
Searle Scholar
Searle Scholars Program
2007-2010
Terman Fellowship
Fredrick E. Terman Foundation
2006-2008
Kimmel Scholar Award
Sidney Kimmel Foundation for Cancer Research
2006-2008
Career Award in the Biomedical Sciences
Burroughs Wellcome Fund
2003 - 2008
Mentored Clinical Scientist Development Award (KO8)
NIA
2002 - 2007
6  honors and awards: view full list
Professional Education
Degree
Awarding Institution
Field of Study
Year of Graduation
M.D.
Harvard Medical School
-
1999
Ph.D.
Harvard Medical School
-
1999
Web Site Links
Research/Lab website:   http://www.stanford.edu/group/gozani/
Research Interests

Chromatin dynamics regulate diverse nuclear processes that influence cellular viability and tumorigenesis. Our research focuses on chromatin modulation by the ING (Inhibitor of Growth) family of tumor suppressor proteins. The goal of our research is to elucidate the molecular mechanism by which ING proteins regulate chromatin under normal conditions and in response to genotoxic insults, and to understand the relationship between these activities and tumor suppressor pathways.

Publications
  • Shi X, Kachirskaia I, Yamaguchi H, West LE, Wen H, Wang EW, Dutta S, Appella E, Gozani O "Modulation of p53 Function by SET8-Mediated Methylation at Lysine 382." Mol Cell 2007; 27: 4: 636-46 More »
  • Matthews AG, Kuo AJ, Ramón-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, Gozani O, Oettinger MA "RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination." Nature 2007; 450: 7172: 1106-10 More »
  • Shi X, Hong T, Walter KL, Ewalt M, Michishita E, Hung T, Carney D, Peña P, Lan F, Kaadige MR, Lacoste N, Cayrou C, Davrazou F, Saha A, Cairns BR, Ayer DE, Kutateladze TG, Shi Y, Côté J, Chua KF, Gozani O "ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression." Nature 2006; More »
  • Lan F, Collins RE, De Cegli R, Alpatov R, Horton JR, Shi X, Gozani O, Cheng X, Shi Y "Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression." Nature 2007; 448: 7154: 718-22 More »
  • Ramón-Maiques S, Kuo AJ, Carney D, Matthews AG, Oettinger MA, Gozani O, Yang W "The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2." Proc Natl Acad Sci U S A 2007; 104: 48: 18993-8 More »
24 publications:   view full list

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