Olivia Martinez
Academic Appointments
- Professor (Research), Surgery - Multi-Organ Transplantation
- Member, Bio-X
- Member, Cancer Center
Contact Information
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Academic Offices
Administrative Contact Sharon Dickow Administrative Associate Email Tel Work 8-6248
Professional Snapshot
Administrative Appointments
- Director, Pre-Doctoral Program, Immunology IDP, Stanford University School of Medicine (2008 - present)
Honors and Awards
- Distinguished Service Award, American Association of Immunologists (2007)
- Faculty Mentor of the Year, Program in Immunology, Stanford University School of Medicine (2005)
- Fujisawa Basica Science Award, American Society of Transplantation (2004)
Education & Community
Professional Education
- Ph.D., Univ of California, Berkeley, Immunology (1982)
- B.S., Univ of Southern California, Biological Sciences (1976)
Graduate & Fellowship Program Affiliations
Scientific Focus
Research Interests
There are two major areas of focus in the laboratory. First, we are interested in Epstein Barr Virus-mediated mechanisms of immune evasion with particular focus on resistance to cell death receptor pathways of apoptosis in EBV B cell lymphomas, the characterization of the human T cell response to EBV infected B cells and effects of immunosuppressive drugs on growth and survival of EBV B cell lymphomas. The second area of study addresses tolerance induction in solid organ transplantation. In particular we are examining the generation and characterization of regulatory T cells in allogeneic responses and the role of alternate co-stimulatory molecules in alloreactivity.
Publications
- Decreases in circulating CD4+CD25hiFOXP3+ cells and increases in intragraft FOXP3+ cells accompany allograft rejection in pediatric liver allograft recipients. "Pediatr Transplant" 2009 ; 1 70-80
- Rapamycin inhibits proliferation of Epstein-Barr virus-positive B-cell lymphomas through modulation of cell-cycle protein expression. "Transplantation" 2007 ; 8 1114-21
- Latent membrane protein 1 of EBV activates phosphatidylinositol 3-kinase to induce production of IL-10. "J Immunol" 2007 ; 12 8225-34
- Epstein-Barr virus: evasive maneuvers in the development of PTLD. "Am J Transplant" 2007 ; 2 271-7
- Mutations to bid cleavage sites protect hepatocytes from apoptosis after ischemia/reperfusion injury. "Transplantation" 2007 ; 6 778-85
